Search Results - "Granziera, Sabrina"
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Free fatty acid receptor 4 inhibitory signaling in delta cells regulates islet hormone secretion in mice
Published in Molecular metabolism (Germany) (01-03-2021)“…Maintenance of glucose homeostasis requires the precise regulation of hormone secretion from the endocrine pancreas. Free fatty acid receptor 4 (FFAR4/GPR120)…”
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Palmitate and oleate modify membrane fluidity and kinase activities of INS-1E β-cells alongside altered metabolism-secretion coupling
Published in Biochimica et biophysica acta. Molecular cell research (01-02-2020)“…Chronic exposure to elevated levels of glucose and free fatty acids impairs beta-cell function, leading to insulin secretion defects and eventually beta-cell…”
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200-OR: Role of Delta Cell Gpr120 in the Regulation of Islet Function and Glucose Control
Published in Diabetes (New York, N.Y.) (01-06-2019)“…Gpr120 is a long-chain fatty acid receptor expressed in pancreatic islets, where it inhibits the secretion of somatostatin (SST) by the δ cell. SST is a…”
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