Search Results - "Grant Prentice, H."

Epigenetic modulation of MAGE-A3 antigen expression in multiple myeloma following treatment with the demethylation agent 5-azacitidine and the histone deacetlyase inhibitor MGCD0103 by Moreno-Bost, Amberly, Szmania, Susann, Stone, Katie, Garg, Tarun, Hoerring, Antje, Szymonifka, Jackie, Shaughnessy, John, Barlogie, Bart, Grant Prentice, H, van Rhee, Frits

“…Abstract Background aims Immunotherapy targeting MAGE-A3 in multiple myeloma (MM) could eradicate highly aggressive and proliferative clonal cell populations…”
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Early and late invasive pneumococcal infection following stem cell transplantation: a European Bone Marrow Transplantation survey by Engelhard, Dan, Cordonnier, Catherine, Shaw, Peter J., Parkalli, Terttu, Guenther, Christine, Martino, Rodrigo, Dekker, Adriaan W., Prentice, H. Grant, Gustavsson, Anita, Nurnberger, Wenzel, Ljungman, Per

“…Streptococcus pneumoniae (S. pneumoniae) may cause severe and lethal infections months and years following stem cell transplantation (SCT). In a prospective…”
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A randomized controlled trial of itraconazole versus fluconazole for the prevention of fungal infections in patients with haematological malignancies by Morgenstern, Godfrey R., Prentice, Archibald G., Grant Prentice, H., Ropner, Janet E., Schey, Stephen A., Warnock, David W.

“…Fluconazole is widely used as antifungal prophylaxis but it is ineffective against Aspergillus. Itraconazole has a broader spectrum of activity but the…”
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Expression of co‐stimulatory molecules on acute myeloid leukaemia blasts may effect duration of first remission by Whiteway, Alastair, Corbett, Tim, Anderson, Robert, Macdonald, Ian, Prentice, H. Grant

“…Many solid tumours have been shown to lack expression of either of the immune co‐stimulatory molecules CD80 (B7·1) or CD86 (B7·2), which is thought to be one…”
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Improving the Outcome of Bone Marrow Transplantation by Using CD52 Monoclonal Antibodies to Prevent Graft-Versus-Host Disease and Graft Rejection by Hale, Geoff, Zhang, Mei-Jie, Bunjes, Donald, Prentice, H. Grant, Spence, David, Horowitz, Mary M., Barrett, A. John, Waldmann, Herman

“…Graft-versus-host disease (GVHD) is a major cause of mortality and morbidity after allogeneic bone marrow transplantation, but can be avoided by removing T…”
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A strategy for treatment of Epstein-Barr virus-positive Hodgkin's disease by targeting interleukin 12 to the tumor environment using tumor antigen-specific T cells by Wagner, Hans-Joachim, Bollard, Catherine M, Vigouroux, Stéphane, Huls, M Helen, Anderson, Robert, Prentice, H Grant, Brenner, Malcolm K, Heslop, Helen E, Rooney, Cliona M

“…Adoptive immunotherapy with Epstein-Barr virus (EBV)-specific cytotoxic T cells (CTL) is effective for the prophylaxis and treatment of EBV-induced lymphoma in…”
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Thrombotic thrombocytopenic purpura after allogeneic stem cell transplantation: a survey of the European Group for Blood and Marrow Transplantation (EBMT) by Ruutu, Tapani, Hermans, Jo, Niederwieser, Dietger, Gratwohl, Alois, Kiehl, Michael, Volin, Liisa, Bertz, Harmut, Ljungman, Per, Spence, David, Verdonck, Leo F., Prentice, H. Grant, Bosi, Alberto, Du Toit, Cecile E., Brinch, Lorentz, Apperley, Jane F.

“…A survey was carried out among the European Group for Blood and Marrow Transplantation (EBMT) centres to determine the incidence, risk factors, treatment and…”
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Fludarabine, cytosine arabinoside, granulocyte‐colony stimulating factor with or without idarubicin in the treatment of high risk acute leukaemia or myelodysplastic syndromes by Virchis, Andres, Koh, Mickey, Rankin, Peter, Mehta, Atul, Potter, Michael, Victor Hoffbrand, A., Grant Prentice, H.

“…Summary The combination of fludarabine (FDR), high dose cytarabine and granulocyte colony stimulating factor (FLAG) with or without idarubicin (Ida) was used…”
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Modelling cytomegalovirus replication patterns in the human host: factors important for pathogenesis by Regoes, Roland R, Frances Bowen, E, Cope, Alethea V, Gor, Dehila, Hassan-Walker, Aycan F, Grant Prentice, H, Johnson, Margaret A, Sweny, Paul, Burroughs, Andrew K, Griffiths, Paul D, Bonhoeffer, Sebastian, Emery, Vincent C

“…Human cytomegalovirus can cause a diverse range of diseases in different immunocompromised hosts. The pathogenic mechanisms underlying these diseases have not…”
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Albumin activates the AKT signaling pathway and protects B-chronic lymphocytic leukemia cells from chlorambucil- and radiation-induced apoptosis by Jones, Dylan T., Ganeshaguru, Kanagasabai, Anderson, Robert J., Jackson, Trevor R., Bruckdorfer, K. Richard, Low, Sylvia Y., Palmqvist, Lars, Prentice, H. Grant, Hoffbrand, A. Victor, Mehta, Atul B., Wickremasinghe, R. Gitendra

“…Activation of the phosphatidylinositol 3- kinase/AKT pathway antagonizes apoptosis in diverse cellular systems. We previously showed that human plasma…”
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Induction therapy for adults with acute lymphoblastic leukemia: results of more than 1500 patients from the international ALL trial: MRC UKALL XII/ECOG E2993 by Rowe, Jacob M., Buck, Georgina, Burnett, Alan K., Chopra, Raj, Wiernik, Peter H., Richards, Susan M., Lazarus, Hillard M., Franklin, Ian M., Litzow, Mark R., Ciobanu, Niculae, Prentice, H. Grant, Durrant, Jill, Tallman, Martin S., Goldstone, Anthony H.

“…The international acute lymphoblastic leukemia (ALL) study was designed to prospectively define the optimal therapy for adults 60 years of age or younger with…”
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The degree of matching at HLA-DPB1 predicts for acute graft-versus-host disease and disease relapse following haematopoietic stem cell transplantation by Shaw, B E, Potter, M N, Mayor, N P, Pay, A L, Smith, C, Goldman, J M, Prentice, H Grant, Marsh, S G E, Madrigal, J A

“…The importance of matching for HLA-DPB1 in unrelated donor haematopoietic stem cell (HSC) transplantation is little understood. Most transplant centres do not,…”
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Non‐MHC‐restricted cytotoxic cells: their roles in the control and treatment of leukaemias by Lowdell, Mark W., Lamb, Lawrence, Hoyle, Christine, Velardi, Andrea, Prentice, H. Grant

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HHV‐6‐related secondary graft failure following allogeneic bone marrow transplantation by Johnston, Rosalynd E., Geretti, Anna‐Maria, Prentice, H. Grant, Clark, A. Duncan, Wheeler, Anne C., Potter, Michael, Griffiths, Paul D.

“…We report the case of an 11‐year‐old boy who underwent allogeneic bone marrow transplantation (BMT) for relapsed acute lymphoblastic leukaemia. Despite…”
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Polymerase chain reaction (PCR)‐ and reverse transcription PCR‐based minimal residual disease detection in long‐term follow‐up of childhood acute lymphoblastic leukaemia by Gameiro, Paula, Moreira, Ilídia, Yetgin, Sevgi, Papaioannou, Mary, Potter, Michael N., Prentice, H. Grant, Hoffbrand, A. Victor, Foroni, Letizia

“…Minimal residual disease (MRD) was investigated in 52 children with acute lymphoblastic leukaemia (ALL), using antigen receptor gene rearrangements and reverse…”
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Mycophenolate mofetil for the treatment of refractory auto‐immune haemolytic anaemia and auto‐immune thrombocytopenia purpura by Howard, Jo, Hoffbrand, A. Victor, Prentice, H. Grant, Mehta, Atul

“…The treatment of both auto‐immune haemolytic anaemia (AIHA) and auto‐immune thromobocytopenic purpura (AITP) remains unsatisfactory in those refractory to…”
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Towards a targeted, risk‐based, antifungal strategy in neutropenic patients by Prentice, H. Grant, Kibbler, ChriS. C., Prentice, ArchiE. G.

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Minimal Residual Disease Tests Provide an Independent Predictor of Clinical Outcome in Adult Acute Lymphoblastic Leukemia by Mortuza, F. Y.

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Malignant neoplasms in long-term survivors of bone Marrow transplantation by KOLB, H. J, SOCIE, G, WICK, R, WEISS, M, PRENTICE, H. G, DUELL, T, VAN LINT, M. T, TICHELLI, A, APPERLEY, J. F, NEKOLLA, E, LJUNGMAN, P, JACOBSEN, N, VAN WEEL, M

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Evidence that continued remission in patients treated for acute leukaemia is dependent upon autologous natural killer cells by Lowdell, Mark W., Craston, Rose, Samuel, David, Wood, Marion E., O'Neill, Elena, Saha, Vaskar, Prentice, H. Grant

“…Although it has been known for more than 40 years that allogeneic immune responses cure leukaemias after bone marrow transplantation, autologous…”
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