Search Results - "Grant M. Zane"
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Filling gaps in bacterial amino acid biosynthesis pathways with high-throughput genetics
Published in PLoS genetics (11-01-2018)“…For many bacteria with sequenced genomes, we do not understand how they synthesize some amino acids. This makes it challenging to reconstruct their metabolism,…”
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2
Adeno-Associated Virus (AAV) Gene Delivery: Dissecting Molecular Interactions upon Cell Entry
Published in Viruses (10-07-2021)“…Human gene therapy has advanced from twentieth-century conception to twenty-first-century reality. The recombinant Adeno-Associated Virus (rAAV) is a major…”
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3
Effect of the Deletion of qmoABC and the Promoter-Distal Gene Encoding a Hypothetical Protein on Sulfate Reduction in Desulfovibrio vulgaris Hildenborough
Published in Applied and Environmental Microbiology (01-08-2010)“…The pathway of electrons required for the reduction of sulfate in sulfate-reducing bacteria (SRB) is not yet fully characterized. In order to determine the…”
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4
The Structure of an AAV5-AAVR Complex at 2.5 Å Resolution: Implications for Cellular Entry and Immune Neutralization of AAV Gene Therapy Vectors
Published in Viruses (18-11-2020)“…Adeno-Associated Virus is the leading vector for gene therapy. Although it is the vector for all in vivo gene therapies approved for clinical use by the US…”
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5
Novel Mode of Molybdate Inhibition of Desulfovibrio vulgaris Hildenborough
Published in Frontiers in microbiology (08-12-2020)“…Sulfate-reducing microorganisms (SRM) are found in multiple environments and play a major role in global carbon and sulfur cycling. Because of their growth…”
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6
Erosion of functional independence early in the evolution of a microbial mutualism
Published in Proceedings of the National Academy of Sciences - PNAS (14-10-2014)“…Significance Nature is full of species that cooperate in mutually beneficial interactions to survive. Some are completely dependent on such relationships. How…”
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Large-scale genetic characterization of the model sulfate-reducing bacterium, Desulfovibrio vulgaris Hildenborough
Published in Frontiers in microbiology (31-03-2023)“…Sulfate-reducing bacteria (SRB) are obligate anaerobes that can couple their growth to the reduction of sulfate. Despite the importance of SRB to global…”
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LurR is a regulator of the central lactate oxidation pathway in sulfate-reducing Desulfovibrio species
Published in PloS one (09-04-2019)“…The central carbon/lactate utilization pathway in the model sulfate-reducing bacterium, Desulfovibrio vulgaris Hildenborough, is encoded by the highly…”
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Mechanisms of Chromium and Uranium Toxicity in Pseudomonas stutzeri RCH2 Grown under Anaerobic Nitrate-Reducing Conditions
Published in Frontiers in microbiology (10-08-2017)“…Chromium and uranium are highly toxic metals that contaminate many natural environments. We investigated their mechanisms of toxicity under anaerobic…”
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Rapid Transposon Liquid Enrichment Sequencing (TnLE-seq) for Gene Fitness Evaluation in Underdeveloped Bacterial Systems
Published in Applied and Environmental Microbiology (01-12-2013)“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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11
Biofilm Interaction Mapping and Analysis (BIMA) of Interspecific Interactions in Pseudomonas Co-culture Biofilms
Published in Frontiers in microbiology (09-12-2021)“…Pseudomonas species are ubiquitous in nature and include numerous medically, agriculturally and technologically beneficial strains of which the interspecific…”
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12
Correction: Filling gaps in bacterial amino acid biosynthesis pathways with high-throughput genetics
Published in PLoS genetics (03-04-2019)“…[This corrects the article DOI: 10.1371/journal.pgen.1007147.]…”
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13
Mechanism for microbial population collapse in a fluctuating resource environment
Published in Molecular systems biology (01-03-2017)“…Managing trade‐offs through gene regulation is believed to confer resilience to a microbial community in a fluctuating resource environment. To investigate…”
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14
Deconstructing the Dissimilatory Sulfate Reduction Pathway: Isotope Fractionation of a Mutant Unable of Growth on Sulfate
Published in Frontiers in microbiology (14-12-2018)“…The sulfur isotope record provides key insight into the history of Earth's redox conditions. A detailed understanding of the metabolisms driving this cycle,…”
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15
Biofilm growth mode promotes maximum carrying capacity and community stability during product inhibition syntrophy
Published in Frontiers in microbiology (15-12-2014)“…Sulfate-reducing bacteria (SRB) can interact syntrophically with other community members in the absence of sulfate, and interactions with hydrogen-consuming…”
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16
New Family of Tungstate-Responsive Transcriptional Regulators in Sulfate-Reducing Bacteria
Published in Journal of Bacteriology (01-10-2013)“…The trace elements molybdenum and tungsten are essential components of cofactors of many metalloenzymes. However, in sulfate-reducing bacteria, high…”
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Functional Characterization of Crp/Fnr-Type Global Transcriptional Regulators in Desulfovibrio vulgaris Hildenborough
Published in Applied and Environmental Microbiology (01-02-2012)“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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18
Genetic basis for nitrate resistance in Desulfovibrio strains
Published in Frontiers in microbiology (21-04-2014)“…Nitrate is an inhibitor of sulfate-reducing bacteria (SRB). In petroleum production sites, amendments of nitrate and nitrite are used to prevent SRB production…”
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19
Deletion of the Desulfovibrio vulgaris Carbon Monoxide Sensor Invokes Global Changes in Transcription
Published in Journal of Bacteriology (01-11-2012)“…The carbon monoxide-sensing transcriptional factor CooA has been studied only in hydrogenogenic organisms that can grow using CO as the sole source of energy…”
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Mutant phenotypes for thousands of bacterial genes of unknown function
Published in Nature (London) (01-05-2018)“…One-third of all protein-coding genes from bacterial genomes cannot be annotated with a function. Here, to investigate the functions of these genes, we present…”
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