Search Results - "Grant, L R"

Concurrent Dexamethasone Limits the Clinical Benefit of Immune Checkpoint Blockade in Glioblastoma by Iorgulescu, J Bryan, Gokhale, Prafulla C, Speranza, Maria C, Eschle, Benjamin K, Poitras, Michael J, Wilkens, Margaret K, Soroko, Kara M, Chhoeu, Chhayheng, Knott, Aine, Gao, Yan, Lim-Fat, Mary Jane, Baker, Gregory J, Bonal, Dennis M, Nguyen, Quang-Dé, Grant, Gareth R L, Ligon, Keith L, Sorger, Peter K, Chiocca, E Antonio, Anderson, Ana C, Kirschmeier, Paul T, Sharpe, Arlene H, Freeman, Gordon J, Reardon, David A

“…Dexamethasone, a uniquely potent corticosteroid, is frequently administered to patients with brain tumors to decrease tumor-associated edema, but limited data…”
Get full text

Experimental and numerical analysis of single-lap joints for the automotive industry by Grant, L.D.R., Adams, R.D., da Silva, Lucas F.M.

“…Lap joints are used extensively in the manufacture of cars. In order to determine the effect of using a structural adhesive instead of spot-welding, a detailed…”
Get full text

Stat4-dependent, T-bet-independent regulation of IL-10 in NK cells by Grant, L R, Yao, Z-J, Hedrich, C M, Wang, F, Moorthy, A, Wilson, K, Ranatunga, D, Bream, J H

“…Interleukin-10 (IL-10) is intensely studied, yet little is known about the mechanisms that control IL-10 expression. We identified striking similarities…”
Get full text

Interface Embrittlement Between 63Sn-37Pb Solder and Au Layer—Part 1: Physical Metallurgy of Liquid-State and Solid-State Reactions by Vianco, P. T., Kilgo, A. C., McKenzie, B. M., Grant, R. L., Williams, S.

“…This study examined the interface microstructure that developed between 63Sn-37Pb (Sn-Pb) solder and the Au protective layer that was not fully consumed during…”
Get full text

Effect of the temperature on the strength of adhesively bonded single lap and T joints for the automotive industry by Grant, L.D.R., Adams, R.D., da Silva, Lucas F.M.

“…Adhesively bonded lap and T joints are used extensively in the manufacture of automotive structures. In order to determine the effect of using a structural…”
Get full text

The Chelsea Critical Care Physical Assessment Tool (CPAx): validation of an innovative new tool to measure physical morbidity in the general adult critical care population; an observational proof-of-concept pilot study by Corner, E.J, Wood, H, Englebretsen, C, Thomas, A, Grant, R.L, Nikoletou, D, Soni, N

“…Abstract Objective To develop a scoring system to measure physical morbidity in critical care – the Chelsea Critical Care Physical Assessment Tool (CPAx)…”
Get full text

Independent dose per monitor unit review of eight U.S.A. proton treatment facilities by Moyers, M. F., Ibbott, G. S., Grant, R. L., Summers, P. A., Followill, D. S.

“…Purpose: Compare the dose per monitor unit at different proton treatment facilities using three different dosimetry methods. Methods: Measurements of dose per…”
Get full text

Quantitative human health risk assessment for 1,3-butadiene based upon ovarian effects in rodents by Kirman, C.R., Grant, R.L.

“…► Meta-analysis was conducted for ovarian toxicity in rodents exposed to 1,3-butadiene. ► Hemoglobin adduct data were used to estimate internal dose for…”
Get full text

Experimental and Numerical Analysis of T-peel Joints for the Automotive Industry by Grant, L. D. R., Adams, R. D., da Silva, Lucas F. M.

“…The T-peel joint is commonly used in the automotive industry, especially in the panels of the load compartment in vans. In order to determine the effect of…”
Get full text

Retinoic acid reduces p11 protein levels in bronchial epithelial cells by a posttranslational mechanism by Gladwin, M T, Yao, X L, Cowan, M, Huang, X L, Schneider, R, Grant, L R, Logun, C, Shelhamer, J H

“…p11 is a member of the S100 family of proteins, is the cellular ligand of annexin II, and interacts with the carboxyl region of 85-kDa cytosolic phospholipase…”
Get more information

Cost effectiveness of COX 2 selective inhibitors and traditional NSAIDs alone or in combination with a proton pump inhibitor for people with osteoarthritis by Latimer, Nicholas, Lord, Joanne, Grant, Robert L, O’Mahony, Rachel, Dickson, John, Conaghan, Philip G

“…Objectives To investigate the cost effectiveness of cyclo-oxygenase-2 (COX 2) selective inhibitors and traditional non-steroidal anti-inflammatory drugs…”
Get full text

Converting an odds ratio to a range of plausible relative risks for better communication of research findings by Grant, Robert L

“…Odds ratios are a necessary evil in medical research; although used as a measure of effect size from logistic regressions and case-control studies, they are…”
Get full text

Comparative toxicity of tetracaine, proparacaine and cocaine evaluated with primary cultures of rabbit corneal epithelial cells by Grant, R L, Acosta, D

“…Cocaine was first used as a topical anesthetic for the eye by Dr Carl Koller in 1884. It became evident that this agent produced erosion of the corneal…”
Get more information

Loss of cytoskeletal support is not sufficient for anoxic plasma membrane disruption in renal cells by Chen, J, Dai, J, Grant, R L, Doctor, R B, Sheetz, M P, Mandel, L J

“…The goal of this study was to determine whether anoxic membrane disruption is initiated by loss of cytoskeletal support in rabbit renal proximal tubules (PT)…”
Get full text

National Clinical Sentinel Audit of Evidence-based Prescribing for Older People by Batty, G. M., Grant, R. L., Aggarwal, R., Lowe, D., Potter, J. M., Pearson, M. G., Jackson, S. H. D.

“…Objectives  To audit the performance of hospitals in evidence‐based prescribing. Setting  All hospitals in England were invited to participate. The audit was…”
Get full text

National sentinel clinical audit of evidence-based prescribing for older people: methodology and development by Grant, R. L., Batty, G. M., Aggarwal, R., Lowe, D., Potter, J. M., Pearson, M. G., Oborne, A., Jackson, S. H. D.

“…Rationale, aims and objectives This national clinical audit aimed to develop and implement a methodology to assess the appropriateness of prescribing for…”
Get full text

Biopsy versus resection for high-grade glioma by Hart, Michael G, Grant, Gareth Rl, Solyom, Emma F, Grant, Robin

“…This is an update of the original review published in the Cochrane Database of Systematic Reviews Issue 1, 2000 and updated in 2003, 2007 and 2010.People with…”
Get more information

Validation of dual-source single-tube reconstruction as a method to obtain half-dose images to evaluate radiation dose and noise reduction: phantom and human assessment using CT colonography and sinogram-affirmed iterative reconstruction (SAFIRE) by Fletcher, Joel G, Grant, Katharine L R, Fidler, Jeff L, Shiung, Maria, Yu, Lifeng, Wang, Jia, Schmidt, Bernhard, Allmendinger, Thomas, McCollough, Cynthia H

“…To evaluate a method for obtaining half-dose CT images for observer studies evaluating lower-dose CT. Phantoms of varying sizes were scanned at multiple tube…”
Get full text

Assessment of an iterative reconstruction algorithm (SAFIRE) on image quality in pediatric cardiac CT datasets by Han, B. Kelly, MD, Grant, Katharine L.R., PhD, Garberich, Ross, MS, Sedlmair, Martin, PhD, Lindberg, Jana, RTR, Lesser, John R., MD

“…Background Pediatric cardiac patients often undergo repeat diagnostic testing, resulting in relatively high cumulative medical radiation exposure. Low-dose CT…”
Get full text

A digitized fluorescence imaging study on the effects of local anesthetics on cytosolic calcium and mitochondrial membrane potential in cultured rabbit corneal epithelial cells by Grant, R L, Acosta, Jr, D

“…It has been documented by several investigators that local anesthetics displace calcium from calcium binding sites and alter the functioning of different…”
Get more information