Search Results - "Grant, David J"

Crystal structures of drugs: advances in determination, prediction and engineering by Grant, David J. W, Datta, Sharmistha

“…Most marketed pharmaceuticals consist of molecular crystals. The arrangement of the molecules in a crystal determines its physical properties and, in certain…”
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Thermodynamics, Molecular Mobility and Crystallization Kinetics of Amorphous Griseofulvin by Zhou, Deliang, Zhang, Geoff G. Z, Law, Devalina, Grant, David J. W, Schmitt, Eric A

“…Griseofulvin is a small rigid molecule that shows relatively high molecular mobility and small configurational entropy in the amorphous phase and tends to…”
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Improving quality through simulation; developing guidance to design simulation interventions following key events in healthcare by Diaz-Navarro, Cristina, Jones, Bridie, Pugh, Gethin, Moneypenny, Michael, Lazarovici, Marc, Grant, David J

“…Simulation educators are often requested to provide multidisciplinary and/or interprofessional simulation training in response to critical incidents. Current…”
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Mechanochromism of Piroxicam Accompanied by Intermolecular Proton Transfer Probed by Spectroscopic Methods and Solid-Phase Changes by Sheth, Agam R, Lubach, Joseph W, Munson, Eric J, Muller, Francis X, Grant, David J. W

“…Structural and solid-state changes of piroxicam in its crystalline form under mechanical stress were investigated using cryogenic grinding, powder X-ray…”
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Influence of crystal structure on the tableting properties of n-alkyl 4-hydroxybenzoate esters (parabens) by Feng, Yushi, Grant, David J W, Sun, Changquan C

“…Certain crystallographic features, such as the existence of slip planes, can greatly facilitate the ability of crystals to deform plastically. An investigation…”
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Influence of crystal structure on the compaction properties of n-alkyl 4-hydroxybenzoate esters (parabens) by YUSHI FENG, GRANT, David J. W

“…The aim of the study is to examine the influence of slip planes on the nanoindentation hardness and compaction properties of methyl, ethyl, n-propyl, and…”
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A calorimetric investigation of thermodynamic and molecular mobility contributions to the physical stability of two pharmaceutical glasses by Zhou, Deliang, Grant, David J W, Zhang, Geoff G Z, Law, Devalina, Schmitt, Eric A

“…The purpose of this work was to investigate the contribution of thermodynamics and mobility to the physical stability of two pharmaceutical glasses with…”
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Stable-form screening: overcoming trace impurities that inhibit solution-mediated phase transformation to the stable polymorph of sulfamerazine by Gong, Yuchuan, Collman, Benjamin M, Mehrens, Shawn M, Lu, Enxian, Miller, Jonathan M, Blackburn, Anthony, Grant, David J W

“…Solution-mediated phase transformation (SMPT) has been used as a focused technique to rapidly identify the stable polymorph of a given substance. Despite ample…”
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Navigating Two Worlds: Understanding the Complexities and Health Implications of Black Fatherhood in Toronto by Grant, David J.

“…This article contends that individual and systemic racist notions against Black fathers contribute to Black fathers' feelings of ineptitude, invisibility and…”
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Improving cardiopulmonary resuscitation with a CPR feedback device and refresher simulations (CPR CARES Study): a randomized clinical trial by Cheng, Adam, Brown, Linda L, Duff, Jonathan P, Davidson, Jennifer, Overly, Frank, Tofil, Nancy M, Peterson, Dawn T, White, Marjorie L, Bhanji, Farhan, Bank, Ilana, Gottesman, Ronald, Adler, Mark, Zhong, John, Grant, Vincent, Grant, David J, Sudikoff, Stephanie N, Marohn, Kimberly, Charnovich, Alex, Hunt, Elizabeth A, Kessler, David O, Wong, Hubert, Robertson, Nicola, Lin, Yiqun, Doan, Quynh, Duval-Arnould, Jordan M, Nadkarni, Vinay M

“…The quality of cardiopulmonary resuscitation (CPR) affects hemodynamics, survival, and neurological outcomes following pediatric cardiopulmonary arrest (CPA)…”
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Workload of Team Leaders and Team Members During a Simulated Sepsis Scenario by Tofil, Nancy M, Lin, Yiqun, Zhong, John, Peterson, Dawn Taylor, White, Marjorie Lee, Grant, Vincent, Grant, David J, Gottesman, Ronald, Sudikoff, Stephanie N, Adler, Mark, Marohn, Kimberly, Davidson, Jennifer, Cheng, Adam

“…Crisis resource management principles dictate appropriate distribution of mental and/or physical workload so as not to overwhelm any one team member. Workload…”
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Training using medical simulation by Grant, David J, Marriage, Stephen C

“…As the time available for medical education is shortened by reductions in training hours and the demands of modern healthcare delivery, educators are…”
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Development of the orpheus perfusion simulator for use in high-fidelity extracorporeal membrane oxygenation simulation by Lansdowne, William, Machin, David, Grant, David J

“…Despite its life-sustaining potential, extracorporeal membrane oxygenation (ECMO) remains a complex treatment modality for which close teamwork is imperative…”
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Formation of Liquid Inclusions in Adipic Acid Crystals during Recrystallization from Aqueous Solutions by Zhang, Geoff G. Z, Grant, David J. W

“…Liquid inclusions consist of pockets of saturated solution entrapped in host crystals during crystallization from solution. Inclusions are contaminants that…”
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Similarity in structures of racemic and enantiomeric ibuprofen sodium dihydrates by Zhang, Yuegang, Grant, David J. W.

“…The crystal structures of two ibuprofen sodium dihydrates, racemic sodium (RS)‐2‐(4‐isobutylphenyl)propanoate dihydrate or (RS)‐NaIBDH, Na+·C13H17O2−·2H2O, and…”
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Influence of crystal structure on the tableting properties of sulfamerazine polymorphs by CHANGQUAN SUN, GRANT, David J. W

“…To understand the influence of polymorphic structure on the tableting properties of sulfamerazine. Bulk powders of sulfamerazine polymorph I and of two…”
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Effect of supersaturation on the crystallization of phenylbutazone polymorphs by Datta, Sharmistha, Grant, David J. W.

“…The article describes the effect of degree of supersaturation, σ, on the crystallization of specific polymorphs of phenylbutazone from its methanolic solution…”
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Physical stability of amorphous pharmaceuticals: Importance of configurational thermodynamic quantities and molecular mobility by Zhou, Deliang, Zhang, Geoff G Z, Law, Devalina, Grant, David J W, Schmitt, Eric A

“…This work relates the thermodynamic quantities (Gc, Hc, and Sc) and the molecular mobility values (1/tau) of five structurally diverse amorphous compounds to…”
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Influence of Elastic Deformation of Particles on Heckel Analysis by Sun, Changquan, Grant, David J. W.

“…The Heckel equation is one of the most useful equations for describing the compaction properties of pharmaceutical powders. Important material properties…”
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Improved tableting properties of p-hydroxybenzoic acid by water of crystallization: a molecular insight by Sun, Changquan, Grant, David J W

“…To understand the influence of water in the crystal structure on the compaction properties of otherwise structurally similar crystals, p-hydroxybenzoic acid…”
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