Search Results - "Grandy, Scott A"
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The association between mental health and shift work: Findings from the Atlantic PATH study
Published in Preventive medicine (01-09-2021)“…We evaluated the relationship between mental health and shift work in the Atlantic Partnership for Tomorrow's Health (PATH) cohort study. In a matched study…”
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Moderate Exercise Has Limited but Distinguishable Effects on the Mouse Microbiome
Published in mSystems (01-07-2017)“…The gut microbiome is known to have a complex yet vital relationship with host health. While both exercise and the gut microbiome have been shown to impact…”
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Exercise to Reduce Anthracycline-Mediated Cardiovascular Complications in Breast Cancer Survivors
Published in Current oncology (Toronto) (13-10-2021)“…While developments in cancer therapeutics have greatly reduced morbidity and mortality in females with breast cancer, it comes at a cost of an increased risk…”
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Exercise Programming Modelling a Standard of Care Approach Improves Physical Health and Patient-Reported Outcomes in Individuals Living with Breast Cancer: A Pilot Study
Published in Current oncology (Toronto) (26-07-2023)“…Controlled study designs widely report that exercise improves the health of individuals living with breast cancer. Still, many individuals living with breast…”
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The Impact of Exercise on Cardiotoxicity in Pediatric and Adolescent Cancer Survivors: A Scoping Review
Published in Current oncology (Toronto) (01-09-2022)“…Childhood and adolescent cancer survivors are disproportionately more likely to develop cardiovascular diseases from the late effects of cardiotoxic therapies…”
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Association between Diet Quality and Adiposity in the Atlantic PATH Cohort
Published in Nutrients (21-10-2017)“…The aim of this study was to examine diet quality among participants in the Atlantic Partnership for Tomorrow's Health (PATH) cohort and to assess the…”
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The Impact of Resistance Exercise on Muscle Mass in Glioblastoma in Survivors (RESIST): Protocol for a Randomized Controlled Trial
Published in JMIR research protocols (04-05-2022)“…Glioblastoma is the most common primary brain malignancy in adults, accounting for approximately 48% of all brain tumors. Standard treatment includes radiation…”
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Overexpression of type 1 angiotensin II receptors impairs excitation-contraction coupling in the mouse heart
Published in American journal of physiology. Heart and circulatory physiology (01-11-2011)“…Transgenic mice that overexpress human type 1 angiotensin II receptor (AT(1)R) in the heart develop cardiac hypertrophy. Previously, we have shown that in 6-mo…”
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Correction: DeClercq, V.; et al. Association between Diet Quality and Adiposity in the Atlantic PATH Cohort. Nutrients 2017, 9 , 1155
Published in Nutrients (26-04-2018)“…The authors request the following corrections to their paper [1]. [...]…”
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Chronic Treatment With the ACE Inhibitor Enalapril Attenuates the Development of Frailty and Differentially Modifies Pro- and Anti-inflammatory Cytokines in Aging Male and Female C57BL/6 Mice
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (12-07-2019)“…Studies on interventions that can delay or treat frailty in humans are limited. There is evidence of beneficial effects of angiotensin converting enzyme (ACE)…”
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Postnatal development has a marked effect on ventricular repolarization in mice
Published in American journal of physiology. Heart and circulatory physiology (01-10-2007)“…To better understand the mechanisms that underlie cardiac repolarization abnormalities in the immature heart, this study characterized and compared K(+)…”
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A Murine Frailty Index Based on Clinical and Laboratory Measurements: Links Between Frailty and Pro-inflammatory Cytokines Differ in a Sex-Specific Manner
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (15-02-2019)“…Abstract A frailty index (FI) based on clinical deficit accumulation (FI-Clinical) quantifies frailty in aging mice. We aimed to develop a laboratory…”
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Aerobic exercise and cardiopulmonary fitness in childhood cancer survivors treated with a cardiotoxic agent: a meta-analysis
Published in Supportive care in cancer (01-07-2018)“…Purpose The main purpose of this review was to synthesize evidence from existing childhood cancer survivor studies that report the effect of aerobic exercise…”
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Aerobic Exercise Attenuates Frailty in Aging Male and Female C57Bl/6 Mice and Effects Systemic Cytokines Differentially by Sex
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (07-01-2022)“…Abstract Aerobic exercise is a promising intervention to attenuate frailty, but preclinical studies have used only male animals. We investigated the impact of…”
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Maladaptive Changes Associated With Cardiac Aging Are Sex-Specific and Graded by Frailty and Inflammation in C57BL/6 Mice
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (01-02-2021)“…Abstract We investigated whether late-life changes in cardiac structure and function were related to high levels of frailty and inflammation in male and female…”
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Burden of multimorbidity and polypharmacy among cancer survivors: a population-based nested case–control study
Published in Supportive care in cancer (01-02-2021)“…Purpose Individuals living with cancer have been shown to have a higher burden of comorbid disease and multimorbidity in comparison to their cancer-free…”
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Multimorbidity in Atlantic Canada and association with low levels of physical activity
Published in Preventive medicine (01-12-2017)“…Owing to an aging population and medical advances, the anticipated growth and prevalence of multimorbidity has been recognized as a significant challenge and…”
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Lifestyle factors and lung cancer risk among never smokers in the Canadian Partnership for Tomorrow’s Health (CanPath)
Published in Cancer causes & control (01-06-2022)“…Background Although smoking is the primary risk factor for lung cancer, 15–25% of lung cancers occur in never smokers. Emerging evidence suggests lifestyle…”
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Cardiovascular disease and physical activity in adult cancer survivors: a nested, retrospective study from the Atlantic PATH cohort
Published in Journal of cancer survivorship (01-04-2017)“…Purpose The study aimed to examine the relationship between cardiovascular disease (CVD) and physical activity (PA) levels in cancer survivors (CS). Methods…”
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