Search Results - "Grandinetti, B."

Dual ALK and CDK4/6 Inhibition Demonstrates Synergy against Neuroblastoma by Wood, Andrew C, Krytska, Kateryna, Ryles, Hannah T, Infarinato, Nicole R, Sano, Renata, Hansel, Theodore D, Hart, Lori S, King, Frederick J, Smith, Timothy R, Ainscow, Edward, Grandinetti, Kathryn B, Tuntland, Tove, Kim, Sunkyu, Caponigro, Giordano, He, You Qun, Krupa, Shiva, Li, Nanxin, Harris, Jennifer L, Mossé, Yaël P

“…Anaplastic lymphoma kinase ( ) is the most frequently mutated oncogene in the pediatric cancer neuroblastoma. We performed an screen for synergistic drug…”
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Overexpression of TRIB2 in human lung cancers contributes to tumorigenesis through downregulation of C EBPα by Grandinetti, K B, Stevens, T A, Ha, S, Salamone, R J, Walker, J R, Zhang, J, Agarwalla, S, Tenen, D G, Peters, E C, Reddy, V A

“…Lung cancer is the most common cause of cancer-related mortality worldwide. Here, we report elevated expression of tribbles homolog 2 (TRIB2) in primary human…”
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FGFR2 promotes breast tumorigenicity through maintenance of breast tumor-initiating cells by Kim, Sungeun, Dubrovska, Anna, Salamone, Richard J, Walker, John R, Grandinetti, Kathryn B, Bonamy, Ghislain M C, Orth, Anthony P, Elliott, Jimmy, Porta, Diana Graus, Garcia-Echeverria, Carlos, Reddy, Venkateshwar A

“…Emerging evidence suggests that some cancers contain a population of stem-like TICs (tumor-initiating cells) and eliminating TICs may offer a new strategy to…”
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Specific requirement of the chromatin modifier mSin3B in cell cycle exit and cellular differentiation by David, Gregory, Grandinetti, Kathryn B, Finnerty, Patricia M, Simpson, Natalie, Chu, Gerald C, DePinho, Ronald A

“…The Sin3-histone deacetylase (HDAC) corepressor complex is conserved from yeast to humans. Mammals possess two highly related Sin3 proteins, mSin3A and mSin3B,…”
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Sin3B: An essential regulator of chromatin modifications at E2F target promoters during cell cycle withdrawal by Grandinetti, Kathryn B., David, Gregory

“…Efficient and accurate cell cycle exit is intimately linked to cellular differentiation, and by inference, to the prevention of tumorigenesis. Perhaps the most…”
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The Irreversible FGFR Inhibitor KIN-3248 Overcomes FGFR2 Kinase Domain Mutations by Balasooriya, Eranga R, Wu, Qibiao, Ellis, Haley, Zhen, Yuanli, Norden, Bryanna L, Corcoran, Ryan B, Mohan, Adithi, Martin, Eric, Franovic, Aleksandra, Tyhonas, John, Lardy, Matthew, Grandinetti, Kathryn B, Pelham, Robert, Soroceanu, Liliana, Silveira, Vanessa S, Bardeesy, Nabeel

“…FGFR2 and FGFR3 show oncogenic activation in many cancer types, often through chromosomal fusion or extracellular domain mutation. FGFR2 and FGFR3 alterations…”
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Loss of one HuD allele on chromosome #1p selects for amplification of the N-myc proto-oncogene in human neuroblastoma cells by GRANDINETTI, K. B, SPENGLER, B. A, BIEDLER, J. L, ROSS, R. A

“…In human neuroblastoma tumors, amplification of the N-myc proto-oncogene and loss of all or part of the short arm of chromosome #1 are both associated with a…”
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MicroRNAs define distinct human neuroblastoma cell phenotypes and regulate their differentiation and tumorigenicity by Samaraweera, Leleesha, Grandinetti, Kathryn B, Huang, Ruojun, Spengler, Barbara A, Ross, Robert A

“…Neuroblastoma (NB) is the most common extracranial solid tumor in children. NB tumors and derived cell lines are phenotypically heterogeneous. Cell lines are…”
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Sin3B Expression Is Required for Cellular Senescence and Is Up-regulated upon Oncogenic Stress by GRANDINETTI, Kathryn B, JELINIC, Petar, DIMAURO, Teresa, PELLEGRINO, Jessica, FERNANDEZ RODRIGUEZ, Rubén, FINNERTY, Patricia M, RUOFF, Rachel, BARDEESY, Nabeel, LOGAN, Susan K, DAVID, Gregory

“…Serial passage of primary mammalian cells or strong mitogenic signals induce a permanent exit from the cell cycle called senescence. A characteristic of…”
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The project 'Metrology for Static and Dynamic Characterization of Supercapacitors' - MetSuperCap by Zucca, M., Al-Zubaidi-R-Smith, N., Bartova, L., Van Den Brom, H., Callegaro, L., Cultrera, A., Fast, L., Grandinetti, B., Hassanzadeh, M., Mariscotti, A., Masouras, A., Musumeci, S., Nicol, G., Ouameur, M., Rietveld, G.

“…Supercapacitors (SCs) represent an environmentally friendly technology, that can replace batteries or work with them in high power density applications. To…”
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Abstract B76: MicroRNAs regulate cell phenotype and N- myc expression in human neuroblastoma cells by Samaraweera, Leleesha, Grandinetti, Kathryn B., Huang, Ruojun, Spengler, Barbara A., Ross, Robert A.

“…Identification of miRNAs that regulate neuroblast growth and differentiation could be important in understanding the onset and progression of the childhood…”
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Overexpression of TRIB2 in human lung cancers contributes to tumorigenesis through downregulation of C/EBP[alpha] by Grandinetti, K B, Stevens, T A, Ha, S, Salamone, R J, Walker, J R, Zhang, J, Agarwalla, S, Tenen, D G, Peters, E C, Reddy, V A

“…Lung cancer is the most common cause of cancer-related mortality worldwide. Here, we report elevated expression of tribbles homolog 2 (TRIB2) in primary human…”
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Sin3B expression is required for cellular senescence and is upregulated upon oncogenic stress by Grandinetti, Kathryn B., Jelinic, Petar, DiMauro, Teresa, Pellegrino, Jessica, Rodriguez, Ruben Fernandez, Finnerty, Patricia M., Ruoff, Rachel, Bardeesy, Nabeel, Logan, Susan K., David, Gregory

“…Serial passage of primary mammalian cells or strong mitogenic signals induces a permanent exit from the cell cycle called senescence. A characteristic of…”
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Our surgical orientation in renal ptosis. Apropos of 185 cases in 10 years by Banchieri, F R, Grandinetti, B, Guadagnin, B, Montalcini, S

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