Search Results - "Grande, Joseph"
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1
Congophilic Fibrillary Glomerulonephritis: A Case Series
Published in American journal of kidney diseases (01-09-2018)“…Congo Red positivity with birefringence under polarized light has traditionally permitted classification of organized glomerular deposits as from amyloid or…”
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2
Renal Disorders in Pregnancy: Core Curriculum 2019
Published in American journal of kidney diseases (01-01-2019)“…As the incidence of chronic kidney disease increases and women pursue pregnancy at more advanced ages, the management of kidney disease in pregnancy has become…”
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3
A practical guide to test blueprinting
Published in Medical teacher (03-08-2019)“…A test blueprint describes the key elements of a test, including the content to be covered, the amount of emphasis allocated to each content area, and other…”
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4
KLF11 deficiency enhances chemokine generation and fibrosis in murine unilateral ureteral obstruction
Published in PloS one (12-04-2022)“…Progression of virtually all forms of chronic kidney disease (CKD) is associated with activation of pro-inflammatory and pro-fibrotic signaling pathways…”
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5
Advances in the pathophysiology of pre-eclampsia and related podocyte injury
Published in Kidney international (01-08-2014)“…Pre-eclampsia is a pregnancy-specific hypertensive disorder that may lead to serious maternal and fetal complications. It is a multisystem disease that is…”
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6
Cell Fusion Connects Oncogenesis with Tumor Evolution
Published in The American journal of pathology (01-07-2015)“…Cell fusion likely drives tumor evolution by undermining chromosomal and DNA stability and/or by generating phenotypic diversity; however, whether a cell…”
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7
VEGF Inhibition, Hypertension, and Renal Toxicity
Published in Current oncology reports (01-08-2012)“…The use of anti-angiogenic agents as part of the therapeutic armamentarium for advanced stage solid tumors has become the standard of care in several…”
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8
Changes in Glomerular Volume, Sclerosis, and Ischemia at 5 Years after Kidney Transplantation: Incidence and Correlation with Late Graft Failure
Published in Journal of the American Society of Nephrology (01-02-2023)“…Glomerular volume, ischemic glomeruli, and global glomerulosclerosis are not consistently assessed on kidney transplant biopsies. The authors evaluated…”
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Correlation of Glomerular Size With Donor–Recipient Factors and With Response to Injury
Published in Transplantation (01-11-2021)“…BACKGROUND:Glomerular size in renal allografts is impacted by donor-recipient factors and response to injury. In serial biopsies of patients with…”
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10
Kidney-resident macrophages promote a proangiogenic environment in the normal and chronically ischemic mouse kidney
Published in Scientific reports (17-09-2018)“…Renal artery stenosis (RAS) caused by narrowing of arteries is characterized by microvascular damage. Macrophages are implicated in repair and injury, but the…”
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11
In Patients with Membranous Lupus Nephritis, Exostosin-Positivity and Exostosin-Negativity Represent Two Different Phenotypes
Published in Journal of the American Society of Nephrology (01-03-2021)“…In patients with secondary (autoimmune) membranous nephropathy, two novel proteins, Exostosin 1 and Exostosin 2 (EXT1/EXT2), are potential disease antigens,…”
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12
Relationship between ETS Transcription Factor ETV1 and TGF-β-regulated SMAD Proteins in Prostate Cancer
Published in Scientific reports (03-06-2019)“…The ETS transcription factor ETV1 is frequently overexpressed in aggressive prostate cancer, which is one underlying cause of this disease. Accordingly,…”
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13
Adipose Tissue-Derived Mesenchymal Stem Cells Improve Revascularization Outcomes to Restore Renal Function in Swine Atherosclerotic Renal Artery Stenosis
Published in Stem cells (Dayton, Ohio) (01-05-2012)“…Reno‐protective strategies are needed to improve renal outcomes in patients with atherosclerotic renal artery stenosis (ARAS). Adipose tissue‐derived…”
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14
Sclerostin alters serum vitamin D metabolite and fibroblast growth factor 23 concentrations and the urinary excretion of calcium
Published in Proceedings of the National Academy of Sciences - PNAS (09-04-2013)“…Inactivating mutations of the SOST (sclerostin) gene are associated with overgrowth and sclerosis of the skeleton. To determine mechanisms by which increased…”
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15
Involvement of RNA helicases p68 and p72 in colon cancer
Published in Cancer research (Chicago, Ill.) (15-08-2007)“…The homologous proteins p68 and p72 are members of the DEAD box family of RNA helicases. Here, we show that expression of both of these helicases strongly…”
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16
Ccl2 deficiency protects against chronic renal injury in murine renovascular hypertension
Published in Scientific reports (05-06-2018)“…Inflammation plays an important role in the pathogenesis of renal and cardiovascular disease in renovascular hypertension (RVH). Ccl2 is an important mediator…”
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17
Urinary Extracellular Vesicles of Podocyte Origin and Renal Injury in Preeclampsia
Published in Journal of the American Society of Nephrology (01-11-2017)“…Renal histologic expression of the podocyte-specific protein, nephrin, but not podocin, is reduced in preeclamptic compared with normotensive pregnancies. We…”
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18
Role of TLR4 signaling in the nephrotoxicity of heme and heme proteins
Published in American journal of physiology. Renal physiology (01-05-2018)“…Destabilized heme proteins release heme, and free heme is toxic. Heme is now recognized as an agonist for the Toll-like receptor-4 (TLR4) receptor. This study…”
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19
Noninvasive Assessment of Renal Fibrosis with Magnetization Transfer MR Imaging: Validation and Evaluation in Murine Renal Artery Stenosis
Published in Radiology (01-04-2017)“…Purpose To test the utility of magnetization transfer imaging in detecting and monitoring the progression of renal fibrosis in mice with unilateral renal…”
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20
Evidence for Antibody-Mediated Injury as a Major Determinant of Late Kidney Allograft Failure
Published in Transplantation (15-07-2010)“…Late graft failure (LGF) is believed to be the consequence of immunologic and nonimmunologic insults leading to progressive deterioration in kidney function…”
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