Search Results - "Grandaliano, G."

Complement Modulation of Anti‐Aging Factor Klotho in Ischemia/Reperfusion Injury and Delayed Graft Function by Castellano, G., Intini, A., Stasi, A., Divella, C., Gigante, M., Pontrelli, P., Franzin, R., Accetturo, M., Zito, A., Fiorentino, M., Montinaro, V., Lucarelli, G., Ditonno, P., Battaglia, M., Crovace, A., Staffieri, F., Oortwijn, B., Amersfoort, E., Pertosa, G., Grandaliano, G., Gesualdo, L.

“…Klotho is an anti‐aging factor mainly produced by renal tubular epithelial cells (TEC) with pleiotropic functions. Klotho is down‐regulated in acute kidney…”
Get full text

Complement-dependent NADPH oxidase enzyme activation in renal ischemia/reperfusion injury by Simone, S., Rascio, F., Castellano, G., Divella, C., Chieti, A., Ditonno, P., Battaglia, M., Crovace, A., Staffieri, F., Oortwijn, B., Stallone, G., Gesualdo, L., Pertosa, G., Grandaliano, G.

“…NADPH oxidase plays a central role in mediating oxidative stress during heart, liver, and lung ischemia/reperfusion injury, but limited information is…”
Get full text

Endothelial-to-mesenchymal transition and renal fibrosis in ischaemia/reperfusion injury are mediated by complement anaphylatoxins and Akt pathway by Curci, Claudia, Castellano, Giuseppe, Stasi, Alessandra, Divella, Chiara, Loverre, Antonia, Gigante, Margherita, Simone, Simona, Cariello, Marica, Montinaro, Vincenzo, Lucarelli, Giuseppe, Ditonno, Pasquale, Battaglia, Michele, Crovace, Antonio, Staffieri, Francesco, Oortwijn, Beatrijs, van Amersfoort, Edwin, Gesualdo, Loreto, Grandaliano, Giuseppe

“…Increasing evidence demonstrates a phenotypic plasticity of endothelial cells (ECs). Endothelial-to-mesenchymal transition (EndMT) contributes to the…”
Get full text

The ratio of epidermal growth factor to monocyte chemotactic peptide-1 in the urine predicts renal prognosis in IgA nephropathy by Torres, D.D., Rossini, M., Manno, C., Mattace-Raso, F., D'Altri, C., Ranieri, E., Pontrelli, P., Grandaliano, G., Gesualdo, L., Schena, F.P.

“…The production of cytokines by resident and non-resident renal cells during immunoglobulin A nephropathy (IgAN) plays a key role in the progression of renal…”
Get full text

Bone morphogenetic protein-2 may represent the molecular link between oxidative stress and vascular stiffness in chronic kidney disease by Dalfino, G, Simone, S, Porreca, S, Cosola, C, Balestra, C, Manno, C, Schena, F.P, Grandaliano, G, Pertosa, G

“…Abstract Oxidative stress and vascular calcifications are emergent risk factors for the accelerated atherosclerosis process featuring chronic kidney disease…”
Get full text

Further phenotypic heterogeneity of CoQ10 deficiency associated with steroid resistant nephrotic syndrome and novel COQ2 and COQ6 variants by Gigante, M., Diella, S., Santangelo, L., Trevisson, E., Acosta, M.J., Amatruda, M., Finzi, G., Caridi, G., Murer, L., Accetturo, M., Ranieri, E., Ghiggeri, G.M., Giordano, M., Grandaliano, G., Salviati, L., Gesualdo, L.

Get full text

IL‐17 Expression by Tubular Epithelial Cells in Renal Transplant Recipients with Acute Antibody‐Mediated Rejection by Loverre, A., Tataranni, T., Castellano, G., Divella, C., Battaglia, M., Ditonno, P., Corcelli, M., Mangino, M., Gesualdo, L., Schena, F. P., Grandaliano, G.

“…Acute rejection is still a common complication of kidney transplantation. IL‐17 is known to be associated with allograft rejection but the cellular source and…”
Get full text

Rapamycin‐Induced Hypophosphatemia and Insulin Resistance Are Associated With mTORC2 Activation and Klotho Expression by Tataranni, T., Biondi, G., Cariello, M., Mangino, M., Colucci, G., Rutigliano, M., Ditonno, P., Schena, F. P., Gesualdo, L., Grandaliano, G.

“…Rapamycin, an immunosuppressive drug used to prevent rejection after kidney transplantation, influences phosphate homeostasis, induces insulin resistance and…”
Get full text

Angiosarcoma of an Arteriovenous Fistula for Hemodialysis in a Kidney Transplant Recipient Affected by Lowe’s Syndrome by Grandaliano, G., Sturniolo, A., Aureli, F., Silvestri, P., D’Ambrosio, V., Ferraro, Pietro Manuel

“…Objective/Background. To describe an uncommon, life-threatening condition such as angiosarcoma of a fistula for hemodialysis occurring in a transplant…”
Get full text

Pharmacogenomics: a new paradigm to personalize treatments in nephrology patients by Zaza, G, Granata, S, Sallustio, F, Grandaliano, G, Schena, F.P

“…Although notable progress has been made in the therapeutic management of patients with chronic kidney disease in both conservative and renal replacement…”
Get full text

Allograft Nephrectomy: What Is the Best Surgical Technique? by Vavallo, A, Lucarelli, G, Bettocchi, C, Tedeschi, M, Palazzo, S, Losappio, V, Gesualdo, L, Grandaliano, G, Selvaggi, F.P, Battaglia, M, Ditonno, P

“…Abstract Background The objective of this study was to evaluate differences in outcomes of allograft nephrectomies performed by extracapsular versus…”
Get full text

Effects of Ischemia-Reperfusion Injury in Kidney Transplantation: Risk Factors and Early and Long-Term Outcomes in a Single Center by Ditonno, P, Impedovo, S.V, Palazzo, S, Bettocchi, C, Gesualdo, L, Grandaliano, G, Selvaggi, F.P, Battaglia, M

“…Abstract Introduction Ischemia-reperfusion injury (IRI) causes a high rate of delayed graft function (DGF), the most frequent complication in the immediate…”
Get full text

Obesity in Kidney Transplantation Affects Renal Function But Not Graft and Patient Survival by Ditonno, P, Lucarelli, G, Impedovo, S.V, Spilotros, M, Grandaliano, G, Selvaggi, F.P, Bettocchi, C, Battaglia, M

“…Abstract Introduction The number of overweight and obese patients undergoing renal transplantation has increased dramatically over the past two decades…”
Get full text

Multidrug-Resistance 1 Gene Single-Nucleotide Polymorphisms Do Not Influence Long-Term Graft Survival After Kidney Transplantation by Saracino, A, Muscaridola, N, Cifarelli, R.A, Stallone, G, Grandaliano, G, Santarsia, G

“…Abstract Background The single-nucleotide polymorphisms (SNPs) of the Multidrug resistance 1 (MDR1) gene have been associated with changes in the…”
Get full text

Hepatitis C virus RNA and core protein in kidney glomerular and tubular structures isolated with laser capture microdissection by Sansonno, D., Lauletta, G., Montrone, M., Grandaliano, G., Schena, F. P., Dammacco, F.

“…Summary The role of hepatits C virus (HCV) in the production of renal injury has been extensively investigated, though with conflicting results. Laser capture…”
Get full text

Middle and Long-term Outcomes of Dual Kidney Transplant: A Multicenter Experience by Impedovo, S.V, De Lorenzis, E, Volpe, A, Gesualdo, L, Grandaliano, G, Palazzo, S, Lucarelli, G, Bettocchi, C, Terrone, C, Stratta, P, Quaglia, M, Battaglia, M, Ditonno, P

“…Abstract Introduction Dual kidney transplantation (DKTx) to reduce the disparity between demand and supply of organs was evaluated in two Italian centers (Bari…”
Get full text

Clinical relevance of cytokine production in hemodialysis by Pertosa, Giovanni, Grandaliano, Giuseppe, Gesualdo, Loreto, Schena, Francesco Paolo

“…Clinical relevance of cytokine production in hemodialysis. Blood–dialyzer interaction in hemodialysis has the potential to activate mononuclear cells leading…”
Get full text

Ischemia–reperfusion injury-induced abnormal dendritic cell traffic in the transplanted kidney with delayed graft function by Loverre, A., Capobianco, C., Stallone, G., Infante, B., Schena, A., Ditonno, P., Palazzo, S., Battaglia, M., Crovace, A., Castellano, G., Ranieri, E., Schena, F.P., Gesualdo, L., Grandaliano, G.

“…Delayed graft function (DGF) in kidney transplantation is associated with an increased risk of acute rejection. Myeloid dendritic cells (DCs) are involved in…”
Get full text

ID2‐VEGF‐related Pathways in the Pathogenesis of Kaposi's Sarcoma: A Link Disrupted by Rapamycin by Stallone, G., Infante, B., Pontrelli, P., Ranieri, E., Loverre, A., Schena, A., Cormio, L., Carrieri, G., Schena, F. P., Grandaliano, G., Gesualdo, L.

“…The Id‐proteins are a family of four related proteins implicated in the control of differentiation and cell‐cycle progression. Down‐regulation of Id‐gene…”
Get full text

Extended Criteria Donor Kidney Transplantation: Comparative Outcome Analysis Between Single versus Double Kidney Transplantation at 5 Years by Lucarelli, G, Bettocchi, C, Battaglia, M, Impedovo, S.V, Vavallo, A, Grandaliano, G, Castellano, G, Schena, F.P, Selvaggi, F.P, Ditonno, P

“…Abstract Introduction Dual kidney transplantation (DKT), using extended criteria donor (ECD) grafts not suitable for single kidney transplantation (SKT), has…”
Get full text