Search Results - "Grand'maison, Francois"
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1
Trial of Minocycline in a Clinically Isolated Syndrome of Multiple Sclerosis
Published in The New England journal of medicine (01-06-2017)“…The risk of conversion from a first demyelinating event to MS was lower with minocycline than with placebo over 6 months but not over 24 months. Changes of…”
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2
Timing of high-efficacy therapy for multiple sclerosis: a retrospective observational cohort study
Published in Lancet neurology (01-04-2020)“…High-efficacy therapies in multiple sclerosis are traditionally used after unsuccessful treatment with first-line disease modifying therapies. We hypothesised…”
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3
Geographical variations in sex ratio trends over time in multiple sclerosis
Published in PloS one (25-10-2012)“…Notes how a female/male (F/M) ratio increase over time in multiple sclerosis (MS) patients has been demonstrated in many countries around the world, but…”
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4
Defining reliable disability outcomes in multiple sclerosis
Published in Brain (London, England : 1878) (01-11-2015)“…Prevention of irreversible disability is currently the most important goal of disease modifying therapy for multiple sclerosis. The disability outcomes used in…”
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5
Cladribine versus fingolimod, natalizumab and interferon β for multiple sclerosis
Published in Multiple sclerosis (01-10-2018)“…Objective: This propensity score–matched analysis from MSBase compared the effectiveness of cladribine with interferon β, fingolimod or natalizumab. Methods:…”
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6
Fingolimod after natalizumab and the risk of short-term relapse
Published in Neurology (08-04-2014)“…OBJECTIVE:To determine early risk of relapse after switch from natalizumab to fingolimod; to compare the switch experience to that in patients switching from…”
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7
Switch to natalizumab versus fingolimod in active relapsing-remitting multiple sclerosis
Published in Annals of neurology (01-03-2015)“…Objective In patients suffering multiple sclerosis activity despite treatment with interferon β or glatiramer acetate, clinicians often switch therapy to…”
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8
Male Sex Is Independently Associated with Faster Disability Accumulation in Relapse-Onset MS but Not in Primary Progressive MS
Published in PloS one (05-06-2015)“…Multiple Sclerosis is more common in women than men and females have more relapses than men. In a large international cohort we have evaluated the effect of…”
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9
Prediction of on-treatment disability worsening in RRMS with the MAGNIMS score
Published in Multiple sclerosis (01-04-2021)“…Background: The magnetic resonance imaging in multiple sclerosis (MAGNIMS) score combines relapses and magnetic resonance imaging (MRI) lesions to predict…”
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10
Discontinuing disease-modifying therapy in MS after a prolonged relapse-free period: a propensity score-matched study
Published in Journal of neurology, neurosurgery and psychiatry (01-10-2016)“…BackgroundDiscontinuation of injectable disease-modifying therapy (DMT) for multiple sclerosis (MS) after a long period of relapse freedom is frequently…”
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11
Comparison Between Dimethyl Fumarate, Fingolimod, and Ocrelizumab After Natalizumab Cessation
Published in JAMA neurology (01-07-2023)“…Natalizumab cessation is associated with a risk of rebound disease activity. It is important to identify the optimal switch disease-modifying therapy strategy…”
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12
Effectiveness of cladribine compared to fingolimod, natalizumab, ocrelizumab and alemtuzumab in relapsing-remitting multiple sclerosis
Published in Multiple sclerosis (01-08-2024)“…Background: Comparisons between cladribine and other potent immunotherapies for multiple sclerosis (MS) are lacking. Objectives: To compare the effectiveness…”
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13
Risk of relapse phenotype recurrence in multiple sclerosis
Published in Multiple sclerosis (01-10-2014)“…Objectives: The aim was to analyse risk of relapse phenotype recurrence in multiple sclerosis and to characterise the effect of demographic and clinical…”
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14
Treatment Response Score to Glatiramer Acetate or Interferon Beta-1a
Published in Neurology (12-01-2021)“…OBJECTIVETo compare the effectiveness of glatiramer acetate (GA) vs intra-muscular Interferon beta-1a (IFNbeta-1a)), we applied a previously published…”
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15
Long-term disability trajectories in primary progressive MS patients: A latent class growth analysis
Published in Multiple sclerosis (01-04-2018)“…Background: Several natural history studies on primary progressive multiple sclerosis (PPMS) patients detected a consistent heterogeneity in the rate of…”
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16
Silent lesions on MRI imaging – Shifting goal posts for treatment decisions in multiple sclerosis
Published in Multiple sclerosis (01-10-2018)“…Background: The current best practice suggests yearly magnetic resonance imaging (MRI) to monitor treatment response in multiple sclerosis (MS) patients…”
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17
Multiple Sclerosis Severity Score (MSSS) improves the accuracy of individualized prediction in MS
Published in Multiple sclerosis (01-10-2022)“…Background: The MSBase prediction model of treatment response leverages multiple demographic and clinical characteristics to estimate hazards of relapses,…”
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18
Quantifying risk of early relapse in patients with first demyelinating events: Prediction in clinical practice
Published in Multiple sclerosis (01-09-2017)“…Background: Characteristics at clinically isolated syndrome (CIS) examination assist in identification of patient at highest risk of early second attack and…”
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19
Contribution of different relapse phenotypes to disability in multiple sclerosis
Published in Multiple sclerosis (01-02-2017)“…Objective: This study evaluated the effect of relapse phenotype on disability accumulation in multiple sclerosis. Methods: Analysis of prospectively collected…”
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20
Identification of Therapeutic Lag in Multiple Sclerosis (1787)
Published in Neurology (14-04-2020)“…Abstract only…”
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