Search Results - "Grams, Estevão Silveira"

Exploring Scaffold Hopping for Novel 2‑(Quinolin-4-yloxy)acetamides with Enhanced Antimycobacterial Activity by Borsoi, Ana Flávia, Silva Ramos, Alessandro, Sperotto, Nathalia, Abbadi, Bruno Lopes, Souza Macchi Hopf, Fernanda, da Silva Dadda, Adilio, Scheibler Rambo, Raoní, Neves Muniz, Mauro, Delgado Paz, Josiane, Silveira Grams, Estevão, Fries da Silva, Fernanda, Pissinate, Kenia, Galina, Luiza, Calle González, Laura, Silva Duarte, Lovaine, Alberton Perelló, Marcia, de Matos Czeczot, Alexia, Bizarro, Cristiano Valim, Basso, Luiz Augusto, Machado, Pablo

“…Utilizing a scaffold-hopping strategy from the drug candidate telacebec, a novel series of 2-(quinolin-4-yloxy)­acetamides was synthesized and evaluated as…”
Get full text

Synthesis and Antimycobacterial Evaluation of N -(4-(Benzyloxy)benzyl)-4-aminoquinolines by Grams, Estevão Silveira, Silva Ramos, Alessandro, Neves Muniz, Mauro, Rambo, Raoní S, Alberton Perelló, Marcia, Sperotto, Nathalia, Calle González, Laura, Duarte, Lovaine Silva, Galina, Luiza, Silva Dadda, Adilio, Arraché Gonçalves, Guilherme, Valim Bizarro, Cristiano, Basso, Luiz Augusto, Machado, Pablo

“…Tuberculosis remains a global health problem that affects millions of people around the world. Despite recent efforts in drug development, new alternatives are…”
Get full text

2‑(Quinolin-4-yloxy)acetamides Are Active against Drug-Susceptible and Drug-Resistant Mycobacterium tuberculosis Strains by Pissinate, Kenia, Villela, Anne Drumond, Rodrigues-Junior, Valnês, Giacobbo, Bruno Couto, Grams, Estêvão Silveira, Abbadi, Bruno Lopes, Trindade, Rogério Valim, Roesler Nery, Laura, Bonan, Carla Denise, Back, Davi Fernando, Campos, Maria Martha, Basso, Luiz Augusto, Santos, Diógenes Santiago, Machado, Pablo

“…2-(Quinolin-4-yloxy)­acetamides have been described as potent in vitro inhibitors of Mycobacterium tuberculosis growth. Herein, additional chemical…”
Get full text

New insights into the SAR and drug combination synergy of 2-(quinolin-4-yloxy)acetamides against Mycobacterium tuberculosis by Giacobbo, Bruno Couto, Pissinate, Kenia, Rodrigues-Junior, Valnês, Villela, Anne Drumond, Grams, Estêvão Silveira, Abbadi, Bruno Lopes, Subtil, Fernanda Teixeira, Sperotto, Nathalia, Trindade, Rogério Valim, Back, Davi Fernando, Campos, Maria Martha, Basso, Luiz Augusto, Machado, Pablo, Santos, Diógenes Santiago

“…2-(Quinolin-4-yloxy)acetamides have been described as potent and selective in vitro inhibitors of Mycobacterium tuberculosis (Mtb) growth. Herein, a new series…”
Get full text