Search Results - "Gramolini, A"

Mass Spectrometry-Based Proteomics: A Useful Tool for Biomarker Discovery? by Gramolini, AO, Peterman, SM, Kislinger, T

“…A biomarker is defined as a biological substance (i.e., protein, metabolite, specific post‐translational modification) that can be used to detect a disease,…”
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Ankyrin-B mutation causes type 4 long-QT cardiac arrhythmia and sudden cardiac death by Bennett, Vann, Mohler, Peter J, Schott, Jean-Jacques, Gramolini, Anthony O, Dilly, Keith W, Guatimosim, Silvia, duBell, William H, Song, Long-Sheng, Haurogné, Karine, Kyndt, Florence, Ali, Mervat E, Rogers, Terry B, Lederer, W. J, Escande, Denis, Marec, Herve Le

“…Mutations in ion channels involved in the generation and termination of action potentials constitute a family of molecular defects that underlie fatal cardiac…”
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286 Elucidation of the protective mechanism of α Crystallin B in cardiomyocytes by Chis, R, Bousette, N, Sharma, P, Miyake, T, Gramolini, A

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375 ERp44 Expression During Zebrafish and Mouse Embryogenesis and Heart Development by Abbasi, C.S, Wang, D, El-Rass, S, Li, J, Backx, P, Cox, B, Wen, X, Gramolini, A

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378 ERp44 Deficiency in Mice, Zebrafish and Mouse-Derived Embryonic Stem Cell Derived Cardiomyocytes Display Aberrant Ca2 Homeostasis, ER Stress Induced Apoptosis and Cardiomyopathy by Wang, D.Y, Abbasi, C, Li, Y.J, El-Rass, S, Tang, G, Dawood, F, Naito, K, Yokoe, S, Wilson, A, Sharma, P, Wen, X.Y, Liu, P, Gramolini, A

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Induction of Utrophin Gene Expression by Heregulin in Skeletal Muscle Cells: Role of the N-Box Motif and GA Binding Protein by Gramolini, Anthony O., Angus, Lindsay M., Schaeffer, Laurent, Burton, Edward A., Tinsley, Jonathon M., Davies, Kay E., Changeux, Jean-Pierre, Jasmin, Bernard J.

“…The modulation of utrophin gene expression in muscle by the nerve-derived factor agrin plausibly involves the trophic factor ARIA/heregulin. Here we show that…”
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The Ankyrin-B C-terminal Domain Determines Activity of Ankyrin-B/G Chimeras in Rescue of Abnormal Inositol 1,4,5-Trisphosphate and Ryanodine Receptor Distribution in Ankyrin-B (−/−) Neonatal Cardiomyocytes by Mohler, Peter J., Gramolini, Anthony O., Bennett, Vann

“…Ankyrins are a closely related family of membrane adaptor proteins that are believed to participate in targeting diverse membrane proteins to specialized…”
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Discordant Expression of Utrophin and Its Transcript in Human and Mouse Skeletal Muscles by Gramolini, Anthony O, Karpati, George, Jasmin, Bernard J

“…In order to determine the mechanisms regulating utrophin expression in human skeletal muscle, we examined the expression and distribution of utrophin and its…”
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Expression of the utrophin gene during myogenic differentiation by Gramolini, Anthony O., Jasmin, Bernard J.

“…The process of myogenic differentiation is known to be accompanied by large increases (∼10-fold) in the expression of genes encoding cytoskeletal and membrane…”
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Increased expression of utrophin in a slow vs. a fast muscle involves posttranscriptional events by Gramolini, A O, Bélanger, G, Thompson, J M, Chakkalakal, J V, Jasmin, B J

“…In addition to showing differences in the levels of contractile proteins and metabolic enzymes, fast and slow muscles also differ in their expression profile…”
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Distinct remodeling pattern between pediatric and adult heart failure: a focus on Ca2+ signaling pathway at proteomic level by Zhang, H, Kuzmanov, U, Urschel, S, Wang, F, Wang, S, Gramolini, A, Oudit, G.Y

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Distinct Regions in the 3′ Untranslated Region Are Responsible for Targeting and Stabilizing Utrophin Transcripts in Skeletal Muscle Cells by Gramolini, Anthony O., Bélanger, Guy, Jasmin, Bernard J.

“…In this study, we have sought to determine whether utrophin transcripts are targeted to a distinct subcellular compartment in skeletal muscle cells, and have…”
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Blocking ATP-sensitive K+ channel during metabolic inhibition impairs muscle contractility by Gramolini, A, Renaud, J M

“…The objectives of this study were to determine the metabolic conditions in which ATP-sensitive K+ channels (K+(ATP) channels) contribute to a decrease in…”
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Identification of Biochemical Adaptations in Hyper- or Hypocontractile Hearts from Phospholamban Mutant Mice by Expression Proteomics by Pan, Yan, Kislinger, Thomas, Gramolini, Anthony O., Zvaritch, Elena, Kranias, Evangelia G., MacLennan, David H., Emili, Andrew

“…Phospholamban (PLN) is a critical regulator of cardiac contractility through its binding to and regulation of the activity of the sarco(endo)plasmic reticulum…”
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Muscle and Neural Isoforms of Agrin Increase Utrophin Expression in Cultured Myotubes via a Transcriptional Regulatory Mechanism by Gramolini, Anthony O., Burton, Edward A., Tinsley, Jonathon M., Ferns, Michael J., Cartaud, Annie, Cartaud, Jean, Davies, Kay E., Lunde, John A., Jasmin, Bernard J.

“…Duchenne muscular dystrophy is a prevalent X-linked neuromuscular disease for which there is currently no cure. Recently, it was demonstrated in a transgenic…”
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Adoptive immunotherapy of human cancer using low-dose recombinant interleukin 2 and lymphokine-activated killer cells by SCHOOF, D. D, GRAMOLINI, B. A, DAVIDSON, D. L, MASSARO, A. F, WILSON, R. E, EBERLEIN, T. J

“…The adoptive transfer of recombinant-methionyl human interleukin 2 (rIL-2)-activated autologous peripheral blood mononuclear lymphokine-activated killer (LAK)…”
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Local Transcriptional Control of Utrophin Expression at the Neuromuscular Synapse by Gramolini, Anthony O., Dennis, Carina L., Tinsley, Jonathon M., Robertson, George S., Cartaud, Jean, Davies, Kay E., Jasmin, Bernard J.

“…Recently, the use of a transgenic mouse model system for Duchenne muscular dystrophy has demonstrated the ability of utrophin to functionally replace…”
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A Novel Mechanism for Modulating Synaptic Gene Expression: Differential Localization of α-Dystrobrevin Transcripts in Skeletal Muscle by Newey, Sarah E., Gramolini, Anthony O., Wu, Jun, Holzfeind, Paul, Jasmin, Bernard J., Davies, Kay E., Blake, Derek J.

“…α-Dystrobrevin is a dystrophin-related and -associated protein that is involved in synapse maturation and is required for normal muscle function. There are…”
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Regulation and functional significance of utrophin expression at the mammalian neuromuscular synapse by Gramolini, Anthony O., Wu, Jun, Jasmin, Bernard J.

“…Duchenne muscular dystrophy (DMD) is caused by the absence of full‐length dystrophin molecules in skeletal muscle fibers. In normal muscle, dystrophin is found…”
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Fetal Cardiac Targets Identify the Autoantibodies Associated with Congenital Heart Block by Benjamin, S, Vi, L, Chatterjee, D, Jaeggi, E, Wahren-Herlenius, M, Ruffatti, A, Hiraki, L, Lohbihler, M, Sepiashvili, L, Laskin, C, Fatah, M, Dominguez, D, Ng, L, Gramolini, A, Christoffels, V, Protze, S, Hamilton, R

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