Search Results - "Grammatopoulos, D. K"

Placental Corticotrophin-Releasing Hormone and its Receptors in Human Pregnancy and Labour: Still a Scientific Enigma by Grammatopoulos, D. K.

“…It is now accepted that, in humans, placental corticotrophin‐releasing hormone (CRH) is involved in the mechanisms controlling the onset of labour; however,…”
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Elevated Fetal Adipsin/Acylation-Stimulating Protein (ASP) in Obese Pregnancy: Novel Placental Secretion via Hofbauer Cells by Sivakumar, K, Bari, M. F, Adaikalakoteswari, A, Guller, S, Weickert, M. O, Randeva, H. S, Grammatopoulos, D. K, Bastie, C. C, Vatish, M

“…Context and Objective: Obesity in pregnancy is associated with increased risks of obesity in the offspring. We investigated the relationship between obesity in…”
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Role of corticotropin-releasing hormone in onset of labour by Grammatopoulos, Dimitris K, Hillhouse, Edward W

“…Corticotropin-releasing hormone (CRH) derived from the placenta is secreted into the maternal circulation in large amounts during the third trimester of human…”
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Expression and signalling characteristics of the corticotrophin-releasing hormone receptors during the implantation phase in the human endometrium by Karteris, E, Papadopoulou, N, Grammatopoulos, DK, Hillhouse, EW

“…Corticotrophin-releasing hormone (CRH) has been identified in several peripheral tissues, including the female reproductive organs. CRH is expressed in the…”
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Reduced Expression of Corticotropin-Releasing Hormone Receptor Type-1α in Human Preeclamptic and Growth-Restricted Placentas by Karteris, E., Goumenou, A., Koumantakis, E., Hillhouse, E. W., Grammatopoulos, D. K.

“…Placentally derived CRH seems to play a major role in the mechanisms controlling human pregnancy and parturition, via activation of specific receptors…”
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Corticotropin-releasing hormone receptor antagonists by Zoumakis, E, Grammatopoulos, D K, Chrousos, G P

“…Corticotropin-releasing hormone (CRH), CRH-related peptides, and CRH receptors play major roles in coordinating the behavioral, endocrine, autonomic, and…”
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Expression and coupling characteristics of the CRH and orexin type 2 receptors in human fetal adrenals by KARTERIS, E, RANDEVA, H. S, GRAMMATOPOULOS, D. K, JAFFE, R. B, HILLHOUSE, E. W

“…Hormones produced by the fetal adrenal regulate fetal growth, steroidogenic activity, and intrauterine homeostasis, which are essential for the maintenance of…”
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Interplay of cAMP and MAPK pathways in hCG secretion and fusogenic gene expression in a trophoblast cell line by Delidaki, M., Gu, M., Hein, A., Vatish, M., Grammatopoulos, D.K.

“…Differentiation of human placental mononuclear trophoblasts into a multinucleate syncytium involves up-regulation of key proteins promoting cell fusion and…”
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The corticotrophin-releasing factor/urocortin system regulates white fat browning in mice through paracrine mechanisms by Lu, B, Diz-Chaves, Y, Markovic, D, Contarino, A, Penicaud, L, Fanelli, F, Clark, S, Lehnert, H, Cota, D, Grammatopoulos, D K, Tabarin, A

“…Objectives: The corticotrophin-releasing factor (CRF)/urocortin system is expressed in the adipose tissue of mammals, but its functional role in this tissue…”
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The Role of Corticotropin-Releasing Hormone Receptors in Placenta and Fetal Membranes during Human Pregnancy by Karteris, E., Grammatopoulos, D.K., Randeva, H.S., Hillhouse, E.W.

“…Corticotropin-releasing hormone (CRH) is a 41 amino acid polypeptide that exerts a wide spectrum of hypothalamic and extrahypothalamic functions. Moreover, the…”
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Expression and Coupling Characteristics of the CRH and Orexin Type 2 Receptors in Human Fetal Adrenals by Karteris, E., Randeva, H. S., Grammatopoulos, D. K., Jaffe, R. B., Hillhouse, E. W.

“…Hormones produced by the fetal adrenal regulate fetal growth, steroidogenic activity, and intrauterine homeostasis, which are essential for the maintenance of…”
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Severe paraneoplastic hypoglycemia secondary to a gastrointestinal stromal tumour masquerading as a stroke by Dimitriadis, G K, Gopalakrishnan, K, Rao, R, Grammatopoulos, D K, Randeva, H S, Weickert, M O, Murthy, N

“…Summary We report the case of a 70-year-old previously healthy female who presented acutely to the Accident and Emergency department with left-sided vasomotor…”
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Corticotropin-Releasing Factor Receptors Couple to Multiple G-Proteins to Activate Diverse Intracellular Signaling Pathways in Mouse Hippocampus: Role in Neuronal Excitability and Associative Learning by Blank, Thomas, Nijholt, Ingrid, Grammatopoulos, Dimitris K, Randeva, Harpal S, Hillhouse, Edward W, Spiess, Joachim

“…Corticotropin-releasing factor (CRF) exerts a key neuroregulatory control on stress responses in various regions of the mammalian brain, including the…”
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Role of stress peptides during human pregnancy and labour by Hillhouse, EW, Grammatopoulos, DK

“…Premature birth is the major source of perinatal death and disability. Furthermore, the intrauterine health of the baby is important for preventing certain…”
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Rat cerebral cortex corticotropin‐releasing hormone receptors: evidence for receptor coupling to multiple G‐proteins by Grammatopoulos, Dimitris K., Randeva, Harpal S., Levine, Michael A., Kanellopoulou, Korinna A., Hillhouse, Edward W.

“…The wide distribution of corticotrophin‐releasing hormone (CRH) receptors in brain and periphery appear to be important in integrating the responses of the…”
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A novel spliced variant of the type 1 corticotropin-releasing hormone receptor with a deletion in the seventh transmembrane domain present in the human pregnant term myometrium and fetal membranes by Grammatopoulos, D K, Dai, Y, Randeva, H S, Levine, M A, Karteris, E, Easton, A J, Hillhouse, E W

“…CRH exerts its actions via activation of specific G protein-coupled receptors, which exist in two types, CRH-R1 and CRH-R2, and arise from different genes with…”
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Potential signalling pathways underlying corticotrophin‐releasing hormone‐mediated neuroprotection from excitotoxicity in rat hippocampus by Elliott‐Hunt, Caroline R., Kazlauskaite, Jurate, Wilde, Geraint J. C., Grammatopoulos, Dimitris K., Hillhouse, Edward W.

“…In several neurological disorders including cerebral ischaemia, glutamate has been implicated as a neurotoxic agent in the mechanisms leading to neuronal cell…”
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Activation of protein kinase C by oxytocin inhibits the biological activity of the human myometrial corticotropin-releasing hormone receptor at term by Grammatopoulos, D K, Hillhouse, E W

“…The role of placental CRH in human pregnancy is currently unknown. The myometrium expresses CRH receptors that during pregnancy become coupled to adenylate…”
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Characterising the corticotropin-releasing hormone (CRH) receptors mediating CRH and urocortin actions during human pregnancy and labour by Hillhouse, E W, Grammatopoulos, D K

“…The mechanism of human labour remains unresolved. One of the most important regulatory signals, however, appears to be corticotropin-releasing hormone (CRH), a…”
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Control of intracellular signalling by corticotropin-releasing hormone in human myometrium by Hillhouse, E W, Grammatopoulos, D K

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