Search Results - "Gramlich, Marius"

Single-Domain Antibodies for Targeting, Detection, and In Vivo Imaging of Human CD4 + Cells by Traenkle, Bjoern, Kaiser, Philipp D, Pezzana, Stefania, Richardson, Jennifer, Gramlich, Marius, Wagner, Teresa R, Seyfried, Dominik, Weldle, Melissa, Holz, Stefanie, Parfyonova, Yana, Nueske, Stefan, Scholz, Armin M, Zeck, Anne, Jakobi, Meike, Schneiderhan-Marra, Nicole, Schaller, Martin, Maurer, Andreas, Gouttefangeas, Cécile, Kneilling, Manfred, Pichler, Bernd J, Sonanini, Dominik, Rothbauer, Ulrich

“…The advancement of new immunotherapies necessitates appropriate probes to monitor the presence and distribution of distinct immune cell populations…”
Get full text

Two birds with one stone: human SIRPα nanobodies for functional modulation and in vivo imaging of myeloid cells by Wagner, Teresa R, Blaess, Simone, Leske, Inga B, Frecot, Desiree I, Gramlich, Marius, Traenkle, Bjoern, Kaiser, Philipp D, Seyfried, Dominik, Maier, Sandra, Rezza, Amélie, Sônego, Fabiane, Thiam, Kader, Pezzana, Stefania, Zeck, Anne, Gouttefangeas, Cécile, Scholz, Armin M, Nueske, Stefan, Maurer, Andreas, Kneilling, Manfred, Pichler, Bernd J, Sonanini, Dominik, Rothbauer, Ulrich

“…Signal-regulatory protein α (SIRPα) expressed by myeloid cells is of particular interest for therapeutic strategies targeting the interaction between SIRPα and…”
Get full text

Discovery of Highly Active Recombinant PNGase H+ Variants Through the Rational Exploration of Unstudied Acidobacterial Genomes by Guo, Rui-Rui, Comamala, Gerard, Yang, Huan-Huan, Gramlich, Marius, Du, Ya-Min, Wang, Ting, Zeck, Anne, Rand, Kasper Dyrberg, Liu, Li, Voglmeir, Josef

“…Peptide- N 4 -( N -acetyl-β-glucosaminyl) asparagine amidases (PNGases, N -glycanases, EC 3.5.1.52) are indispensable tools in releasing N -glycans from…”
Get full text

HDX-MS for Epitope Characterization of a Therapeutic ANTIBODY Candidate on the Calcium-Binding Protein Annexin-A1 by Gramlich, Marius, Hays, Henry C W, Crichton, Scott, Kaiser, Philipp D, Heine, Anne, Schneiderhan-Marra, Nicole, Rothbauer, Ulrich, Stoll, Dieter, Maier, Sandra, Zeck, Anne

“…Annexin-A1 (ANXA1) belongs to a class of highly homologous Ca -dependent phospholipid-binding proteins. Its structure consists of a core region composed of…”
Get full text

A Novel PNGase Rc for Improved Protein N‑Deglycosylation in Bioanalytics and Hydrogen–Deuterium Exchange Coupled With Mass Spectrometry Epitope Mapping under Challenging Conditions by Gramlich, Marius, Maier, Sandra, Kaiser, Philipp D., Traenkle, Bjoern, Wagner, Teresa R., Voglmeir, Josef, Stoll, Dieter, Rothbauer, Ulrich, Zeck, Anne

“…N-linked glycosylation is a ubiquitous posttranslational modification of proteins. While it plays an important role in the biological function of proteins, it…”
Get full text

NeutrobodyPlex—monitoring SARS-CoV-2 neutralizing immune responses using nanobodies by Wagner, Teresa R, Ostertag, Elena, Kaiser, Philipp D, Gramlich, Marius, Ruetalo, Natalia, Junker, Daniel, Haering, Julia, Traenkle, Bjoern, Becker, Matthias, Dulovic, Alex, Schweizer, Helen, Nueske, Stefan, Scholz, Armin, Zeck, Anne, Schenke-Layland, Katja, Nelde, Annika, Strengert, Monika, Walz, Juliane S, Zocher, Georg, Stehle, Thilo, Schindler, Michael, Schneiderhan-Marra, Nicole, Rothbauer, Ulrich

“…In light of the COVID-19 pandemic, there is an ongoing need for diagnostic tools to monitor the immune status of large patient cohorts and the effectiveness of…”
Get full text

Development of a PNGase Rc Column for Online Deglycosylation of Complex Glycoproteins during HDX-MS by Lambert, Thomas, Gramlich, Marius, Stutzke, Luisa, Smith, Luke, Deng, Dingyu, Kaiser, Philipp D., Rothbauer, Ulrich, Benesch, Justin L. P., Wagner, Cornelia, Koenig, Maximiliane, Pompach, Petr, Novak, Petr, Zeck, Anne, Rand, Kasper D.

“…Protein glycosylation is one of the most common PTMs and many cell surface receptors, extracellular proteins, and biopharmaceuticals are glycosylated. However,…”
Get full text