Search Results - "Graichen, Ralph"

Cell therapy and the safety of embryonic stem cell-derived grafts by Hentze, Hannes, Graichen, Ralph, Colman, Alan

“…Recent developments in the identification, in vitro culture and differentiation of stem cells point to the unprecedented potential of these cells, or their…”
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Enhanced cardiomyogenesis of human embryonic stem cells by a small molecular inhibitor of p38 MAPK by Graichen, Ralph, Xu, Xiuqin, Braam, Stefan R., Balakrishnan, Thavamalar, Norfiza, Siti, Sieh, Shirly, Soo, Set Yen, Tham, Su Chin, Mummery, Christine, Colman, Alan, Zweigerdt, Robert, Davidson, Bruce P.

“…Human embryonic stem cells (hESC) can differentiate to cardiomyocytes in vitro but with generally poor efficiency. Here, we describe a novel method for the…”
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Survival and maturation of human embryonic stem cell-derived cardiomyocytes in rat hearts by Dai, Wangde, Field, Loren J, Rubart, Michael, Reuter, Sean, Hale, Sharon L, Zweigerdt, Robert, Graichen, Ralph E, Kay, Gregory L, Jyrala, Aarne J, Colman, Alan, Davidson, Bruce P, Pera, Martin, Kloner, Robert A

“…Abstract Human embryonic stem cell (hESC)-derived cardiomyocytes are a promising cell source for cardiac repair. Whether these cells can be transported long…”
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MicroRNA expression pattern of undifferentiated and differentiated human embryonic stem cells by Lakshmipathy, Uma, Love, Brad, Goff, Loyal A, Jörnsten, Rebecka, Graichen, Ralph, Hart, Ronald P, Chesnut, Jonathan D

“…Many of the currently established human embryonic stem (hES) cell lines have been characterized extensively in terms of their gene expression profiles and…”
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Signal transduction via the growth hormone receptor by Zhu, Tao, Goh, Eyleen L.K, Graichen, Ralph, Ling, Ling, Lobie, Peter E

“…Rapid progress has been made recently in the definition of growth hormone (GH) receptor signal transduction pathways. It is now apparent that many cytokines,…”
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Ernährungsrevolution 2.0 by Weingarten, Melanie, Graichen, Ralph, Nagler, Peter

“…Zusammenfassung Bevölkerung und Bedarf an Nahrungsmitteln wachsen rasant. Einhergehend steigt der Wohlstand der Menschen – vor allem in Asien. Innovation und…”
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The Growth Hormone-binding Protein Is a Location-dependent Cytokine Receptor Transcriptional Enhancer by Graichen, Ralph, Sandstedt, Jonas, Goh, Eyleen L K, Isaksson, Olle G P, Törnell, Jan, Lobie, Peter E

“…In the rat, a growth hormone-binding protein (GHBP) exists that is derived from the growth hormone (GH) receptor gene by an alternative mRNA splicing mechanism…”
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Ernährungsrevolution 2.0: Ernährung und Essen – Teil 1: Alternative Proteine für eine nachhaltige Zukunft by Weingarten, Melanie, Graichen, Ralph, Nagler, Peter

“…Zusammenfassung Bevölkerung und Bedarf an Nahrungsmitteln wachsen rasant. Einhergehend steigt der Wohlstand der Menschen – vor allem in Asien. Innovation und…”
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Glycolipid-independent Sorting of a Secretory Glycoprotein to the Apical Surface of Polarized Epithelial Cells by Graichen, Ralph, Lösch, Angelika, Appel, Dagmar, Koch-Brandt, Claudia

“…Proteins attached to the membrane by a glycosylphosphatidylinositol (GPI)-anchor cluster together with glycolipids in detergent-insoluble complexes at the site…”
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Chemically defined medium supporting cardiomyocyte differentiation of human embryonic stem cells by Xu, Xiu Qin, Graichen, Ralph, Soo, Set Yen, Balakrishnan, Thavamalar, Bte Rahmat, Siti Norfiza, Sieh, Shirly, Tham, Su Chin, Freund, Christian, Moore, Jennifer, Mummery, Christine, Colman, Alan, Zweigerdt, Robert, Davidson, Bruce P.

“…Many applications of human embryonic stem cells (hESCs) will require fully defined growth and differentiation conditions including media devoid of fetal calf…”
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Autocrine Human Growth Hormone Inhibits Placental Transforming Growth Factor-β Gene Transcription to Prevent Apoptosis and Allow Cell Cycle Progression of Human Mammary Carcinoma Cells by Graichen, Ralph, Liu, DongXu, Sun, Yi, Lee, Kok-Onn, Lobie, Peter E.

“…Multiple cellular effects of human growth hormone (hGH) are mediated by an indirect mechanism requiring transcriptional activation of genes encoding protein…”
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Abstract 1471: Development and Characterization of Force Generating Human Engineered Heart Tissue from Embryonic Stem Cells by Rogge, Christina, Didié, Michael, Wettwer, Erich, Ravens, Ursula, Graichen, Ralph, Xu, Xiuqin Q, Colman, Alan, Davidson, Bruce, Zweigerdt, Robert, Eschenhagen, Thomas, Zimmermann, Wolfram H

“…Abstract only Engineered Heart Tissue (EHT) from neonatal rat cardiomyocytes has been used successfully as in vitro model and in cardiac repair. Here, we…”
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Caveolar Internalization of Growth Hormone by Lobie, Peter E., Sadir, Rabia, Graichen, Ralph, Mertani, Hichem C., Morel, Gérard

“…Caveolae are plasma membrane specializations formed by caveolin and characterized by their dependence on membrane cholesterol for structural integrity. We have…”
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Autocrine Human Growth Hormone Inhibits Placental Transforming Growth Factor-β Gene Transcription to Prevent Apoptosis and Allow Cell Cycle Progression of Human Mammary Carcinoma Cells by Ralph Graichen, DongXu Liu, Yi Sun, Kok-Onn Lee, Peter E. Lobie

“…Multiple cellular effects of human growth hormone (hGH) are mediated by an indirect mechanism requiring transcriptional activation of genes encoding protein…”
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Growth Hormone-Induced Reorganization of the Actin Cytoskeleton Is Not Required for STAT5 (Signal Transducer and Activator of Transcription-5)-Mediated Transcription by Goh, Eyleen L. K., Pircher, Tony J., Wood, Timothy J. J., Norstedt, Gunnar, Graichen, Ralph, Lobie, Peter E.

“…Abstract We have investigated the effect of GH on the organization of the actin cytoskeleton within the cell. Human GH (hGH) treatment (50 nm) of Chinese…”
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Sorting of gp80 (GPIII, clusterin), a marker protein for constitutive apical secretion in Madin-Darby canine kidney (MDCK) cells, into the regulated pathway in the pheochromocytoma cell line PC12 by Appel, D, Pilarsky, C, Graichen, R, Koch-Brandt, C

“…We have studied the biogenesis and transport of a marker protein for constitutive apical secretion in Madin-Darby canine kidney (MDCK) cells, the gp80…”
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Growth Hormone-Induced Reorganization of the Actin Cytoskeleton Is Not Required for STAT5 (Signal Transducer and Activator of Transcription-5)-Mediated Transcription1 by Goh, Eyleen L. K, Pircher, Tony J, Wood, Timothy J. J, Norstedt, Gunnar, Graichen, Ralph, Lobie, Peter E

“…We have investigated the effect of GH on the organization of the actin cytoskeleton within the cell. Human GH (hGH) treatment (50 nm) of Chinese hamster ovary…”
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