Search Results - "Graham, Theodore C."

Infusion of Donor Lymphocytes into Stable Canine Radiation Chimeras: Implications for Mechanism of Transplantation Tolerance by Weiden, Paul L, Storb, Rainer, Tsoi, Mang-So, Graham, Theodore C, Lerner, Kenneth G, Thomas, E. Donnall

“…Canine radiation chimeras were used to investigate further mechanism(s) responsible for maintaining the stable chimeric state. Chimeras were studied 7 to 46…”
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Immunologic Reactivity in Canine Marrow Graft Recipients by Ochs, Hans D, Storb, Rainer, Thomas, E. Donnal, Kolb, Hans-Jochem, Graham, Theodore C, Mickelson, Eric, Parr, Marlen, Rudolph, Robert H

“…Abstract Immune reactivity was studied in 55 dogs between 20 days and 8 years after lethal total body irradiation (TBI) or cyclophosphamide (CY) and grafting…”
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The Influence of Transfusions from Unrelated Donors upon Marrow Grafts Between Histocompatible Canine Siblings by Storb, Rainer, Rudolph, Robert H, Graham, Theodore C, Thomas, E. Donnall

“…Abstract Previous studies indicated that marrow grafts between canine siblings matched by serologic histocompatibility typing and for non-reactivity in mixed…”
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Effect of Prior Blood Transfusions on Marrow Grafts: Abrogation of Sensitization by Procarbazine and Antithymocyte Serum by Storb, Rainer, Floersheim, Georg L, Weiden, Paul L, Graham, Theodore C, Kolb, Hans-Jochem, Lerner, Kenneth G, Schroeder, Maria-Louise, Thomas, E. Donnall

“…Abstract Previous studies have shown that a single blood transfusion can immunize a dog and lead to rejection of a subsequent marrow graft even when donor and…”
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Canine Radiation Chimeras: An Attempt to Demonstrate Serum Blocking Factors by an in Vivo Approach by Schroeder, Maria-Louise, Storb, Rainer, Graham, Theodore C, Weiden, Paul L

“…An attempt was made to demonstrate in vivo the presence of blocking factors in the serum of canine chimeras with grafts of chimeric skin onto the marrow donor…”
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Canine Marrow Transplantation: Are Serum Blocking Factors Necessary to Maintain the Stable Chimeric State? by Tsoi, Mang-So, Storb, Rainer, Weiden, Paul L, Graham, Theodore C, Schroeder, Maria-Louise, Thomas, E. Donnall, Jacinto, Pacita

“…Nine long-term canine radiation chimeras and their canine histocompatibility locus (DL-A) compatible, mixed leukocyte culture negative littermate marrow donors…”
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DLA-Identical Bone Marrow Grafts After Low-Dose Total Body Irradiation: Effects of High-Dose Corticosteroids and Cyclosporine on Engraftment by Yu, Cong, Storb, Rainer, Mathey, Bruce, Deeg, H. Joachim, Schuening, Friedrich G., Graham, Theodore C., Seidel, Kristy, Burnett, Robert, Wagner, John L., Shulman, Howard, Sandmaier, Brenda M.

“…Previous studies found that marrow allografts from DLA-identical littermates resulted in survival of 60% of recipient dogs after an otherwise lethal dose of…”
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Canine Hemophilia and Hemopoietic Grafting by Storb, Rainer, Marchioro, Thomas L., Graham, Theodore C., Willemin, Mary, Hougie, Cecil, Thomas, E. Donnall

“…Two hemophilic beagles were given 1200 R whole-body irradiation followed by a successful marrow graft from a normal sibling. During observation periods of 7…”
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Retrovirus-mediated gene transduction into long-term repopulating marrow cells of dogs by SCHUENING, F. G, KAWAHARA, K, HACKMAN, R, OSBORNE, W. R. A, STORB, R, DUSTY MILLER, A, TO, R, GOEHLE, S, STEWART, D, MULLALLY, K, FISHER, L, GRAHAM, T. C, APPELBAUM, F. R

“…Amphotropic helper-free retrovirus vectors containing the bacterial neomycin phosphotransferase gene (neo) and the human adenosine deaminase gene (adenosine…”
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Fractionated versus single-dose total body irradiation at low and high dose rates to condition canine littermates for DLA-identical marrow grafts by Storb, R, Raff, RF, Appelbaum, FR, Deeg, HJ, Graham, TC, Schuening, FG, Sale, G, Bryant, E, Seidel, K

“…We explored in dogs the immunosuppressive properties of 450 cGy total body irradiation (TBI) delivered from two opposing 60Co sources, as assessed by the…”
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Effect of Recombinant Human Granulocyte Colony-Stimulating Factor on Hematopoiesis of Normal Dogs and on Hematopoietic Recovery After Otherwise Lethal Total Body Irradiation by Schuening, Friedrich G., Storb, Rainer, Goehle, Sondra, Graham, Theodore C., Appelbaum, Frederick R., Hackman, Robert, Souza, Lawrence M.

“…This study was designed to test whether recombinant human G-CSF (rh G-CSF) affects hematopoiesis in normal dogs and, if so, to test the effects of G-CSF in…”
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Transplantation of retrovirus-transduced canine keratinocytes expressing the beta-galactosidase gene by Stockschläder, M A, Schuening, F G, Graham, T C, Storb, R

“…We studied transplantation of retrovirus vector transduced canine keratinocytes to determine whether keratinocytes could persist and express the transferred…”
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Effect of Recombinant Canine Granulocyte-Macrophage Colony-Stimulating Factor on Hematopoietic Recovery After Otherwise Lethal Total Body Irradiation by Nash, Richard A., Schuening, Friedrich G., Seidel, Kristy, Appelbaum, Frederick R., Boone, Thomas, Deeg, H. Joachim, Graham, Theodore C., Hackman, Robert, Sullivan-Pepe, Margaret, Storb, Rainer

“…Recombinant canine granulocyte-macrophage colony-stimulating factor (rcGM-CSF) was studied in normal dogs and in dogs receiving otherwise lethal total body…”
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Comparison of Fractionated to Single-Dose Total Body Irradiation in Conditioning Canine Littermates for DLA-Identical Marrow Grafts by Storb, Rainer, Raff, Robert F., Appelbaum, Frederick R., Graham, Theodore C., Schuening, Friedrich G., Sale, George, Pepe, Margaret

“…We explored the ability of fractionated total body irradiation (TBI) given at a rate of 7 cGy/min from opposing dual ∞Co sources at otherwise lethal doses of…”
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DLA-Identical Bone Marrow Grafts After Low-Dose Total Body Irradiation: The Effect of Canine Recombinant Hematopoietic Growth Factors by Storb, Rainer, Raff, Robert F., Appelbaum, Frederick R., Deeg, H. Joachim, Graham, Theodore C., Schuening, Friedrich G., Shulman, Howard, Yu, Cong, Bryant, Eileen, Burnett, Robert, Seidel, Kristy

“…Previous studies found that bone marrow (BM) allografts from DLA-identical littermates resulted in survival of two thirds of recipient dogs after otherwise…”
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Prevention of Transfusion-Induced Graft-Versus-Host Disease in Dogs by Ultraviolet Irradiation by Joachim Deeg, H., Graham, Theodore C., Gerhard-Miller, Lisa, Appelbaum, Frederick R., Schuening, Friedrich, Storb, Rainer

“…Ten dogs were given 9.2 Gy of total body irradiation and autologous bone marrow infusion followed by ten daily transfusions of leukocytes for a total of 11.5…”
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DLA-identical marrow grafts after low-dose total-body irradiation. Addition of viable donor peripheral blood mononuclear cells does not enhance engraftment by Storb, R, Raff, R F, Deeg, H J, Graham, T C, Schuening, F G, Shulman, H, Bryant, E

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Ultraviolet Irradiation of Blood Prevents Transfusion-Induced Sensitization and Marrow Graft Rejection in Dogs by Deeg, H. Joachim, Aprile, Joseph, Graham, Theodore C., Appelbaum, Frederick R., Storb, I Rainer

“…In a canine model using DLA-identical littermate pairs, we have shown that a regimen of three transfusions of donor blood given 24, 17, and 10 days before…”
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What Radiation Dose for DLA-Identical Canine Marrow Grafts? by Storb, Rainer, Raff, Robert F., Appelbaum, Frederick R., Schuening, Friedrich W., Sandmaier, Brenda M., Graham, Theodore C., Donnall Thomas, E.

“…In view of reported attempts at marrow grafting after nuclear accidents with a broad range of radiation exposures, the present study explored the total-body…”
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Studies of the use of L-leucyl-L-leucine methyl ester in canine allogeneic marrow transplantation by Raff, R F, Severns, E M, Storb, R, Graham, T C, Sale, G, Schuening, F G, Appelbaum, F R

“…L-leucyl-L-leucine methyl ester (Leu-Leu-OMe) is a lysosomotropic agent that selectively kills cytotoxic T cells and their precursors, natural killer cells,…”
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