Search Results - "Graham, S.V."

HPV-16 E5 down-regulates expression of surface HLA class I and reduces recognition by CD8 T cells by Campo, M.S, Graham, S.V, Cortese, M.S, Ashrafi, G.H, Araibi, E.H, Dornan, E.S, Miners, K, Nunes, C, Man, S

“…Abstract HPV-16 is the major causes of cervical cancer. Persistence of infection is a necessary event for progression of the infection to cancer. Among other…”
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The RNA stability regulator HuR regulates L1 protein expression in vivo in differentiating cervical epithelial cells by Cumming, S.A, Chuen-Im, T, Zhang, J, Graham, S.V

“…Abstract Human papillomavirus (HPV) L1 and L2 capsid protein expression is restricted to the granular layer of infected, stratified epithelia and is regulated…”
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Regulation of poly(A) binding protein during herpes simplex virus infection by Larralde-Diaz, O.G, Smith, R.W.P, Malik, P, Graham, S.V, Gray, N.K

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Droplet digital PCR quantification suggests that higher viral load correlates with improved survival in HPV-positive oropharyngeal tumours by Stevenson, A., Wakeham, K., Pan, J., Kavanagh, K., Millan, D., Bell, S., McLellan, D., Graham, S.V., Cuschieri, K.

“…•Quantification of HPV viral load in oropharyngeal cancer is possible with droplet PCR.•A high viral load is indicative of improved clinical outcome.•Viral…”
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Penile cancer and the HPV attributable fraction in Scotland; A retrospective cohort study by Cuschieri, K., Pan, J., O Donnell, M., Kirkwood, K., Kavanagh, K., Pollock, K.G., Bhatia, R., Graham, S.V., Wakeham, K.

“…•Prevalence of HPV in a Scottish Cohort of Penile Cancers was 43 %.•The HPV component did not change over a 10 year period.•The rise in Penile Cancer is…”
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A Prospective Cohort Study of Human Papillomavirus-Driven Oropharyngeal Cancers: Implications for Prognosis and Immunisation by Wakeham, K., Pan, J., Pollock, K.G., Millan, D., Bell, S., McLellan, D., McPhaden, A., Conway, D.I., Graham, S.V., Kavanagh, K., Cuschieri, K.

“…Oropharyngeal cancer (OPC) is increasing on a global scale, including the component driven by high-risk human papillomavirus (HR-HPV); contemporary data that…”
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RNA splicing factors regulated by HPV16 during cervical tumour progression by Mole, Sarah, McFarlane, Melanie, Chuen-Im, Thanaporn, Milligan, Steven G, Millan, David, Graham, Sheila V

“…The most prevalent human papillomaviruses (HPVs) causing cervical disease are the 'high-risk' HPV types 16 and 18. All papillomaviruses express a transcription…”
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Evaluation of the clinical maxim: "If it ain't broke, don't fix it" by Howell-Duffy, Chris, Hrynchak, Patricia K, Irving, Elizabeth L, Mouat, Graham S V, Elliott, David B

“…A significant number of patients return to optometric practice dissatisfied with their spectacles. An important question is whether any of these cases are…”
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Regulation of splicing-associated SR proteins by HPV-16 by Mole, S, Veerapraditsin, T, McPhillips, M G, Graham, S V

“…HPV-16 (human papillomavirus type 16) is a small dsDNA (double-stranded DNA) virus which infects mucosal epithelial tissue of the cervix. Epithelial tissue is…”
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trypanosome metacyclic VSG gene promotor with two functionally distinct, life cycle stage-specific activities by Graham, S.V, Wymer, B, Barry, J.D

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Duplicative activation mechanisms of two trypanosome telomeric VSG genes with structurally simple 5' flanks by Matthews, K.R, Shiels, P.G, Graham, S.V, Cowan, C, Barry, J.D

“…In the mammalian bloodstream, African trypanosomes express variant surface glycoprotein (VSG) genes from a family of long and complex telomeric expression…”
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Distinct, developmental stage-specific activation mechanisms of trypanosome VSG genes by Graham, S V, Matthews, K R, Shiels, P G, Barry, J D

“…The metacyclic form of African trypanosomes is the first to express genes for the Variant Surface Glycoprotein (VSG) and it uses an unusually predictable…”
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Trypanosoma brucei: unusual expression-site-associated gene homologies in a metacyclic VSG gene expression site by Graham, S V, Matthews, K R, Barry, J D

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Mechanisms of stage-regulated gene expression in kinetoplastida by Graham, S.V.

“…During their life cycle, trypanosomatid parasites of mammals encounter substantially different environments in their hosts and insect vectors, to which they…”
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Concomitant transcriptional and post-transcriptional control of mRNA abundance during human myeloid cell differentiation by GRAHAM, S. V, BIRNIE, G. D

“…The mechanisms controlling the expression of two genes during the differentiation of HL60 cells have been studied. The relative abundance of one mRNA,…”
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