Search Results - "Graham, Ross"
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Making sense of algorithms: Relational perception of contact tracing and risk assessment during COVID-19
Published in Big data & society (01-01-2021)“…Governments and citizens of nearly every nation have been compelled to respond to COVID-19. Many measures have been adopted, including contact tracing and risk…”
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Using analytical performance specifications in a medical laboratory
Published in Clinical chemistry and laboratory medicine (26-07-2024)“…Analytical performance specifications (APS) are used for the quantitative assessment of assay analytical performance, with the aim of providing information…”
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Revisiting fine-tuning in the MSSM
Published in The journal of high energy physics (01-03-2017)“…A bstract We evaluate the amount of fine-tuning in constrained versions of the minimal supersymmetric standard model (MSSM), with different boundary conditions…”
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A unified model of quarks and leptons with a universal texture zero
Published in The journal of high energy physics (01-03-2018)“…A bstract We show that a universal texture zero in the (1,1) position of all fermionic mass matrices, including heavy right-handed Majorana neutrinos driving a…”
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On the MSSM Higgsino mass and fine tuning
Published in Physics letters. B (10-08-2016)“…It is often argued that low fine tuning in the MSSM necessarily requires a rather light Higgsino. In this note we show that this need not be the case when a…”
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Phase II Trial of Pertuzumab and Trastuzumab in Patients With Human Epidermal Growth Factor Receptor 2–Positive Metastatic Breast Cancer That Progressed During Prior Trastuzumab Therapy
Published in Journal of clinical oncology (01-03-2010)“…PURPOSE; Pertuzumab, a human epidermal growth factor receptor 2 (HER2) -targeted monoclonal antibody, potently inhibits HER2 dimerization and HER-mediated…”
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5-year analysis of neoadjuvant pertuzumab and trastuzumab in patients with locally advanced, inflammatory, or early-stage HER2-positive breast cancer (NeoSphere): a multicentre, open-label, phase 2 randomised trial
Published in The lancet oncology (01-06-2016)“…Summary Background In the primary analysis of the NeoSphere trial, patients given neoadjuvant pertuzumab, trastuzumab, and docetaxel showed a significantly…”
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Unification and fermion mass structure
Published in Physics letters. B (12-06-2008)“…Grand Unified Theories predict relationships between the GUT-scale quark and lepton masses. Using new data in the context of the MSSM, we update the values and…”
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The generalised NMSSM at one loop: fine tuning and phenomenology
Published in The journal of high energy physics (01-08-2012)“…We determine the degree of fine tuning needed in a generalised version of the NMSSM that follows from an underlying or R symmetry. We find that it is…”
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Pertuzumab, trastuzumab, and docetaxel for HER2-positive metastatic breast cancer (CLEOPATRA study): overall survival results from a randomised, double-blind, placebo-controlled, phase 3 study
Published in The lancet oncology (01-05-2013)“…Summary Background CLEOPATRA is a phase 3 study to compare the efficacy and safety of pertuzumab, trastuzumab, and docetaxel with placebo, trastuzumab, and…”
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Discrete R symmetries for the MSSM and its singlet extensions
Published in Nuclear physics. B (01-09-2011)“…We determine the anomaly free discrete R symmetries, consistent with the MSSM, that commute with SU ( 5 ) and suppress the μ parameter and nucleon decay. We…”
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Non-universal gaugino masses and fine tuning implications for SUSY searches in the MSSM and the GNMSSM
Published in The journal of high energy physics (01-11-2013)“…A bstract For the case of the MSSM and the most general form of the NMSSM (GN-MSSM) we determine the reduction in the fine tuning that follows from allowing…”
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Analytical performance specifications for EQA schemes - need for harmonisation
Published in Clinical chemistry and laboratory medicine (01-05-2015)“…External Quality Assurance (EQA) is a vital tool in laboratory medicine to assess individual laboratory analytical performance and also the differences between…”
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A new approach to gauge coupling unification and proton decay
Published in The journal of high energy physics (01-04-2019)“…A bstract An analytical formalism, including RG running at two loop order, is used to link the supersymmetric and GUT spectra in any GUT model in which the…”
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Efficacy and safety of neoadjuvant pertuzumab and trastuzumab in women with locally advanced, inflammatory, or early HER2-positive breast cancer (NeoSphere): a randomised multicentre, open-label, phase 2 trial
Published in The lancet oncology (2012)“…Summary Background Studies with pertuzumab, a novel anti-HER2 antibody, show improved efficacy when combined with the established HER2-directed antibody…”
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Pertuzumab Monotherapy After Trastuzumab-Based Treatment and Subsequent Reintroduction of Trastuzumab: Activity and Tolerability in Patients With Advanced Human Epidermal Growth Factor Receptor 2–Positive Breast Cancer
Published in Journal of clinical oncology (10-05-2012)“…The combination of pertuzumab and trastuzumab resulted in a clinical benefit rate (CBR) of 50% in patients with human epidermal growth factor receptor 2 (HER2)…”
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Measurement uncertainty for clinical laboratories - a revision of the concept
Published in Clinical chemistry and laboratory medicine (01-08-2016)“…The uncertainty of a measurement result is a fundamental concept in metrology indicating the range within the "true" value of a measurement should lie…”
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Estimating Reference Change Values Using Routine Patient Data: A Novel Pathology Database Approach
Published in Clinical chemistry (Baltimore, Md.) (04-11-2024)“…Abstract Background The reference change value (RCV) is calculated by combining the within-subject biological variation (CVI) and local analytical variation…”
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Rebuilding public health on more than thoughts and prayers
Published in Canadian journal of public health (01-08-2021)“…Sweeping reviews will be conducted once the COVID-19 pandemic concludes to support public health system strengthening. Unfortunately, these reviews will find…”
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Bordetella Pertussis virulence factors in the continuing evolution of whooping cough vaccines for improved performance
Published in Medical microbiology and immunology (01-02-2018)“…Despite high vaccine coverage, whooping cough caused by Bordetella pertussis remains one of the most common vaccine-preventable diseases worldwide…”
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