Search Results - "Graham, Richard T."
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Chaetocin-mediated SUV39H1 inhibition targets stemness and oncogenic networks of diffuse midline gliomas and synergizes with ONC201
Published in Neuro-oncology (Charlottesville, Va.) (05-04-2024)“…Diffuse intrinsic pontine gliomas (DIPG/DMG) are devastating pediatric brain tumors with extraordinarily limited treatment options and uniformly fatal…”
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Venous thromboembolism in children with central nervous system tumors: Comparison of an institutional cohort to a national administrative database
Published in Pediatric blood & cancer (01-03-2021)“…Background Central nervous system (CNS) tumors are the second most common malignancy of childhood, and published data on venous thromboembolism (VTE) rate and…”
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Multi‐institutional analysis of central nervous system germ cell tumors in patients with Down syndrome
Published in Pediatric blood & cancer (01-10-2022)“…Purpose Primary germ cell tumors (GCTs) are the most common central nervous system (CNS) neoplasm in patients with Down syndrome (DS). However, a standard of…”
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Prognostic factors for patients with relapsed central nervous system nongerminomatous germ cell tumors
Published in Pediatric blood & cancer (01-01-2022)“…We aimed toidentify prognostic factors that may help better understand the behavior of relapsed central nervous system nongerminomatous germ cell tumors. We…”
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Pediatric Gliosarcoma With and Without Neurofibromatosis Type 1: A Whole-exome Comparison of 2 Patients
Published in Journal of pediatric hematology/oncology (01-11-2021)“…Gliosarcoma is rare among pediatric patients and among individuals with Neurofibromatosis Type 1 (NF1). Here we compare 2 pediatric gliosarcoma patients, one…”
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Multi‐institutional analysis of treatment modalities in basal ganglia and thalamic germinoma
Published in Pediatric blood & cancer (01-10-2021)“…Background Central nervous system (CNS) germinomas are treatment‐sensitive tumors with excellent survival outcomes. Current treatment strategies combine…”
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QOL-23. Expanded protocols for hearing loss related cisplatin-based therapy in childhood cancer patients
Published in Neuro-oncology (Charlottesville, Va.) (03-06-2022)“…Abstract BACKGROUND: Most children who require cisplatin chemotherapy incur hearing loss. The basal end of the cochlea, corresponding to high frequency sound…”
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BIOL-05. IDENTIFICATION AND VALIDATION OF PA2G4 AS A POTENTIAL THERAPEUTIC TARGET IN PEDIATRIC DIFFUSE GLIOMAS
Published in Neuro-oncology (Charlottesville, Va.) (12-06-2023)“…Abstract Brain tumors are the second most common pediatric malignancy after leukemia. High grade gliomas have a significantly high morbidity and mortality in…”
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GCT-29. MULTI-INSTITUTIONAL ANALYSIS OF PEDIATRIC RELAPSED/REFRACTORY CENTRAL NERVOUS SYSTEM GERMINOMAS
Published in Neuro-oncology (Charlottesville, Va.) (18-06-2024)Get full text
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GCT-15. Multi-institutional analysis and literature review of central nervous system germ cell tumors in patients with Down syndrome
Published in Neuro-oncology (Charlottesville, Va.) (03-06-2022)“…Abstract BACKGROUND: A standard-of-care has not been established for the management of patients with Down syndrome (DS) who develop primary central nervous…”
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PATH-15. PROTEOMIC SIGNATURES PREDICT GRADE IN PEDIATRIC AND YOUNG ADULT INFILTRATIVE ASTROCYTOMAS
Published in Neuro-oncology (Charlottesville, Va.) (04-12-2020)“…Abstract BACKGROUND Infiltrative astrocytomas in children and young adults pose a treatment challenge due to the difficulty of achieving gross total resection…”
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MBCL-06. SUCCESSFUL SALVAGE OF DESMOPLASTIC NODULAR MEDULLOBLASTOMA PATIENTS TREATED ON ACNS1221
Published in Neuro-oncology (Charlottesville, Va.) (22-06-2018)“…Abstract Desmoplastic nodular medulloblastoma (DNMB) is among the most treatable pediatric brain tumors with overall survival often reported in the range of…”
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MBRS-73. AN EXPLORATORY ANALYSIS LOOKING AT THE ASSOCIATION OF GERMLINE CODING MUTATIONS WITH IMPAIRED DEVELOPMENT AND ADAPTIVE BEHAVIOR FUNCTION IN PEDIATRIC MEDULLOBLASTOMA PATIENTS TREATED ON HEAD START 4
Published in Neuro-oncology (Charlottesville, Va.) (04-12-2020)“…Abstract Children with brain tumors often carry germline mutations known to contribute to tumorigenesis and treatment response; however, little is known about…”
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HGG-30. PEDIATRIC GLIOSARCOMA WITH AND WITHOUT NEUROFIBROMATOSIS TYPE 1: A WHOLE-EXOME COMPARISON OF TWO PATIENTS
Published in Neuro-oncology (Charlottesville, Va.) (22-06-2018)“…Abstract BACKGROUND/OBJECTIVE Gliosarcoma is a WHO grade IV histologic variant of glioblastoma that occurs very rarely among pediatric patients, even more so…”
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GCT-23. MULTI-INSTITUTIONAL ANALYSIS OF TREATMENT MODALITIES IN BASAL GANGLIA AND THALAMIC GERMINOMA
Published in Neuro-oncology (Charlottesville, Va.) (04-12-2020)“…Abstract BACKGROUND Central nervous system (CNS) germinomas are radiotherapy (RT)-sensitive tumors with excellent survival. Current treatment strategies…”
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HGG-30. PEDIATRIC GLIOSARCOMA WITH AND WITHOUT NEUROFIBROMATOSIS TYPE 1: A WHOLE-EXOME COMPARISON OF TWO PATIENTS
Published in Neuro-oncology (Charlottesville, Va.) (22-06-2018)Get full text
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Content Reading and the Recreation of Meaning
Published in English journal (01-02-1987)Get full text
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