Search Results - "Graham, Cathy L"

Evaluation of percutaneous vacuum assisted intact specimen breast biopsy device for ultrasound visualized breast lesions: Upstage rates and long term follow-up for high risk lesions and DCIS by Graham, Cathy L., MD

“…Abstract Objective Percutaneous core biopsy of ultrasound visualized breast lesions is standard for diagnosis. Large gauge vacuum-assisted core needles have…”
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Antimicrobial Activities of Jadomycin B and Structurally Related Analogues by JAKEMAN, David L, BANDI, Srinivasulu, GRAHAM, Cathy L, REID, Taryn R, WENTZELL, Jason R, DOUGLAS, Susan E

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Diverse DNA-Cleaving Capacities of the Jadomycins through Precursor-Directed Biosynthesis by Cottreau, Krista M, Spencer, Colin, Wentzell, Jason R, Graham, Cathy L, Borissow, Charles N, Jakeman, David L, McFarland, Sherri A

“…Gel mobility assays were used to establish that some members of the jadomycin family of natural products act as DNA cleaving agents. Moreover, it was found…”
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Stereochemical Integrity of Oxazolone Ring-Containing Jadomycins by Borissow, Charles N., Graham, Cathy L., Syvitski, Ray T., Reid, Taryn R., Blay, Jonathan, Jakeman, David L.

“…The jadomycins are a series of natural products produced by Streptomyces venzuelae ISP5230 in response to ethanol shock. A unique structural feature of these…”
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Prospective investigation of amino acid transport and PSMA-targeted positron emission tomography for metastatic lobular breast carcinoma by Mushtaq, Aliza, Lawal, Ismaheel O., Muzahir, Saima, Friend, Sarah C., Bhave, Manali, Meisel, Jane L., Torres, Mylin A., Styblo, Toncred M., Graham, Cathy L., Kalinsky, Kevin, Switchenko, Jeffrey, Ulaner, Gary Allan, Schuster, David M.

“…Purpose To explore the feasibility of imaging amino-acid transport and PSMA molecular pathways in the detection of metastatic breast invasive lobular carcinoma…”
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Jadomycins are cytotoxic to ABCB1-, ABCC1-, and ABCG2-overexpressing MCF7 breast cancer cells by Issa, Mark E, Hall, Steven R, Dupuis, Stephanie N, Graham, Cathy L, Jakeman, David L, Goralski, Kerry B

“…Multidrug resistance remains a major obstacle in the effective treatment of metastatic breast cancer. One mechanism by which multidrug resistance is conferred…”
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Culture conditions improving the production of jadomycin B by JAKEMAN, David L, GRAHAM, Cathy L, YOUNG, Wendy, VINING, Leo C

“…The jadomycins are a unique family of benzoxazolophenanthridine antibiotics produced by Streptomyces venezuelae ISP5230 following heat or ethanol shock or…”
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Isolation and characterization of jadomycin L from Streptomyces venezuelae ISP5230 for solid tumor efficacy studies by Jakeman, David L., Dupuis, Stephanie N., Graham, Cathy L.

“…Precursor-directed biosynthesis offers opportunities to modify natural products and obtain structurally complex metabolites without the need for chemical…”
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Copper-mediated nuclease activity of jadomycin B by Monro, Susan M.A., Cottreau, Krista M., Spencer, Colin, Wentzell, Jason R., Graham, Cathy L., Borissow, Charles N., Jakeman, David L., McFarland, Sherri A.

“…[Display omitted] The natural product jadomycin B, isolated from Streptomyces venezeulae ISP5230, has been found to cleave DNA in the presence of Cu(II) ions…”
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Ring-Opening Dynamics of Jadomycin A and B and Dalomycin T by Syvitski, Ray T, Borissow, Charles N, Graham, Cathy L, Jakeman, David L

“…A novel oxazolone ring-opening and interconversion process between the two jadomycin diastereomeric forms has been characterized by NMR spectroscopy. An…”
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Substrate flexibility of a 2,6-dideoxyglycosyltransferase by Jakeman, David L, Borissow, Charles N, Graham, Cathy L, Timmons, Shannon C, Reid, Taryn R, Syvitski, Ray T

“…We report the first 2,6-dideoxysugar-O-glycosyltransferase with substrate flexibility at the 2 position, confirm the function of a putative NDP-hexose…”
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Novel and expanded jadomycins incorporating non-proteogenic amino acids by Jakeman, David L., Graham, Cathy L., Reid, Taryn R.

“…Jadomycin B is a secondary metabolite produced, in response to stress, by Streptomyces venezuelae ISP5230 grown in nutrient-deprived media. We present…”
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Investigation of the cytotoxcity of novel jadomycins in drug resistant breast cancer cells by Goralski, Kerry B, Graham, Cathy L, Issa, Mark, Jakeman, David L

“…Abstract only The drug transporter ABCB1 plays a major role in drug resistance and chemotherapy failure in the treatment of breast cancer. Jadomycins are…”
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