Search Results - "Gragerov, Alexander"

The Role of Kisspeptin GPR54 Signaling in the Tonic Regulation and Surge Release of Gonadotropin-Releasing Hormone/Luteinizing Hormone by Dungan, Heather M, Gottsch, Michelle L, Zeng, Hongkui, Gragerov, Alexander, Bergmann, John E, Vassilatis, Demetrios K, Clifton, Donald K, Steiner, Robert A

“…The Kiss1 gene codes for kisspeptin, which binds to GPR54, a G-protein-coupled receptor. Kisspeptin and GPR54 are expressed in discrete regions of the…”
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Thyrotropin-Releasing Hormone Receptor 1-Deficient Mice Display Increased Depression and Anxiety-Like Behavior by Zeng, Hongkui, Schimpf, Brian A, Rohde, Alex D, Pavlova, Maria N, Gragerov, Alexander, Bergmann, John E

“…TRH is a neuropeptide with a variety of hormonal and neurotransmitter/neuromodulator functions. In particular, TRH has pronounced acute antidepressant effects…”
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An inducible and reversible mouse genetic rescue system by Zeng, Hongkui, Horie, Kyoji, Madisen, Linda, Pavlova, Maria N, Gragerova, Galina, Rohde, Alex D, Schimpf, Brian A, Liang, Yuqiong, Ojala, Ethan, Kramer, Farah, Roth, Patricia, Slobodskaya, Olga, Dolka, Io, Southon, Eileen A, Tessarollo, Lino, Bornfeldt, Karin E, Gragerov, Alexander, Pavlakis, George N, Gaitanaris, George A

“…Inducible and reversible regulation of gene expression is a powerful approach for uncovering gene function. We have established a general method to efficiently…”
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Structural Analysis of Substrate Binding by the Molecular Chaperone DnaK by Zhu, Xiaotian, Zhao, Xun, Burkholder, William F., Gragerov, Alexander, Ogata, Craig M., Gottesman, Max E., Hendrickson, Wayne A.

“…DnaK and other members of the 70-kilodalton heat-shock protein (hsp70) family promote protein folding, interaction, and translocation, both constitutively and…”
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Neuromedin U Receptor 2-Deficient Mice Display Differential Responses in Sensory Perception, Stress, and Feeding by Zeng, Hongkui, Gragerov, Alexander, Hohmann, John G., Pavlova, Maria N., Schimpf, Brian A., Xu, Hui, Wu, Long-Jun, Toyoda, Hiroki, Zhao, Ming-Gao, Rohde, Alex D., Gragerova, Galina, Onrust, Rene, Bergmann, John E., Zhuo, Min, Gaitanaris, George A.

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Human Immunodeficiency Virus Type 1 (HIV-1) Accessory Protein Vpr Induces Transcription of the HIV-1 and Glucocorticoid-Responsive Promoters by Binding Directly to p300/CBP Coactivators by Kino, Tomoshige, Gragerov, Alexander, Slobodskaya, Olga, Tsopanomichalou, Maria, Chrousos, George P, Pavlakis, George N

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The HIV-1 virion-associated protein vpr is a coactivator of the human glucocorticoid receptor by Kino, T, Gragerov, A, Kopp, J B, Stauber, R H, Pavlakis, G N, Chrousos, G P

“…The HIV-1 virion-associated accessory protein Vpr affects both viral replication and cellular transcription, proliferation, and differentiation. We report that…”
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Vpr Protein of Human Immunodeficiency Virus Type 1 Binds to 14-3-3 Proteins and Facilitates Complex Formation with Cdc25C: Implications for Cell Cycle Arrest by KINO, Tomoshige, GRAGEROV, Alexander, VALENTIN, Antonio, TSOPANOMIHALOU, Maria, ILYINA-GRAGEROVA, Galina, ERWIN-COHEN, Rebecca, CHROUSOS, George P, PAVLAKIS, George N

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Large-scale, saturating insertional mutagenesis of the mouse genome by Gragerov, Alexander, Horie, Kyoji, Pavlova, Maria, Madisen, Linda, Zeng, Hongkui, Gragerova, Galina, Rhode, Alex, Dolka, Io, Roth, Patricia, Ebbert, Amanda, Moe, Stephanie, Navas, Christopher, Finn, Eric, Bergmann, John, Vassilatis, Demetrios K, Pavlakis, George N, Gaitanaris, George A

“…We describe the construction of a large-scale, orderly assembly of mutant ES cells, generated with retroviral insertions and having mutational coverage in >90%…”
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Analysis of the contribution of galanin receptors 1 and 2 to the central actions of galanin-like peptide by Krasnow, Stephanie M, Hohmann, John G, Gragerov, Alexander, Clifton, Donald K, Steiner, Robert A

“…Galanin-like peptide (GALP) shares partial sequence identity with galanin and exhibits agonistic activity at two of the galanin receptor subtypes (GALR1 and…”
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Neurofilament (NF) Assembly; Divergent Characteristics of Human and Rodent NF-L Subunits by Carter, J, Gragerov, A, Konvicka, K, Elder, G, Weinstein, H, Lazzarini, R A

“…Previous studies have shown that rodent neurofilaments (NF) are obligate heteropolymers requiring NF-L plus either NF-M or NF-H for filament formation. We have…”
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Selection of targeted mutants from a library of randomly mutagenized ES cells by Horie, Kyoji, Gaitanaris, George, Gragerov, Alexander

“…A method for random relatively unbiased mutagenesis of ES cells with a mutagenic retroviral vector is described. An orderly assembly of mutant ES cells in…”
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The Evolution of Lipophilin Genes from Invertebrates to Tetrapods: DM-20 Cannot Replace Proteolipid Protein in CNS Myelin by Stecca, Barbara, Southwood, Cherie M, Gragerov, Alexander, Kelley, Kevin A, Friedrich, Victor L., Jr, Gow, Alexander

“…The proteolipid protein (PLP) gene encodes two myelin-specific protein isoforms, DM-20 and PLP, which are members of the highly conserved lipophilin family of…”
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An ARS element from Drosophila melanogaster telomeres contains the yeast ARS core and bent replication enhancer by GRAGEROV, A. I, DANILEVSKAYA, O. N, DIDICHENKO, S. A, KAVERINA, E. N

“…We have sequenced the 0.7-kb-long fragment of Drosophila DNA which ensures the autonomous replication of plasmids in yeast. Deletion mapping has shown the ARS…”
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Specificity of DnaK-peptide binding by Gragerov, A, Zeng, L, Zhao, X, Burkholder, W, Gottesman, M E

“…The sequence specificity of DnaK substrate binding has been studied using a peptide display library. Based on the amino acid patterns that appeared in this…”
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An Inducible and Reversible Mouse Genetic Rescue System: e1000069 by Zeng, Hongkui, Horie, Kyoji, Madisen, Linda, Pavlova, Maria N, Gragerova, Galina, Rohde, Alex D, Schimpf, Brian A, Liang, Yuqiong, Ojala, Ethan, Kramer, Farah, Roth, Patricia, Slobodskaya, Olga, Dolka, Io, Southon, Eileen A, Tessarollo, Lino, Bornfeldt, Karin E, Gragerov, Alexander, Pavlakis, George N, Gaitanaris, George A

“…Inducible and reversible regulation of gene expression is a powerful approach for uncovering gene function. We have established a general method to efficiently…”
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Different peptide binding specificities of hsp70 family members by Gragerov, A, Gottesman, M E

“…A set of heptapeptides was used to compare the relative peptide affinities of three proteins of the hsp70 family: bacterial DnaK, mammalian cytosolic hsc70,…”
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Cooperation of GroEL/GroES and DnaK/DnaJ Heat Shock Proteins in Preventing Protein Misfolding in Escherichia coli by Gragerov, Alexander, Nudler, Evgeny, Komissarova, Natalia, Gaitanaris, George A., Gottesman, Max E., Nikiforov, Vadim

“…Newly synthesized proteins aggregate extensively in Escherichia coli rpoH mutants, which are deficient in the heat shock proteins (hsp). Overproduction of…”
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HHR23A, the Human Homologue of the Yeast Repair Protein RAD23, Interacts Specifically with Vpr Protein and Prevents Cell Cycle Arrest but Not the Transcriptional Effects of Vpr by Gragerov, Alexander, Kino, Tomoshige, Ilyina-Gragerova, Galina, Chrousos, George P., Pavlakis, George N.

“…Yeast two-hybrid selection of proteins interacting with human immunodeficiency virus type 1 Vpr identified HHR23A, a human homologue of the yeast DNA repair…”
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Conservation of topology, but not conformation, of the proteolipid proteins of the myelin sheath by Gow, A, Gragerov, A, Gard, A, Colman, D R, Lazzarini, R A

“…The proteolipid protein gene products DM-20 and PLP are adhesive intrinsic membrane proteins that make up >/=50% of the protein in myelin and serve to…”
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