Search Results - "Graff, R D"

Altered Sensitivity of Posttranslationally Modified Microtubules to Methylmercury in Differentiating Embryonal Carcinoma-Derived Neurons by Graff, R.D., Falconer, M.M., Brown, D.L., Reuhl, K.R.

“…The effects of methylmercury (MeHg) on microtubules (MTs) in differentiating neurons derived from retinoic acid-induced embryonal carcinoma (EC) cells in…”
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A neocartilage ideal for extracellular matrix macromolecule immunolocalization by Parikh, A B, Lee, G M, Tchivilev, I V, Graff, R D

“…A neocartilage construct readily amenable to microscopy and biomechanical studies is described. Porcine articular cartilage was digested with a mixture of…”
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Comparison of gene expression profile between human chondrons and chondrocytes: a cDNA microarray study by Zhang, Z., Fan, J., Becker, K.G., Graff, R.D., Lee, G.M., Francomano, C.A.

“…The chondron is a basic unit of articular cartilage that includes the chondrocyte and its pericellular matrix (PCM). This current study was designed to…”
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The effect of glutathione depletion on methyl mercury-induced microtubule disassembly in cultured embryonal carcinoma cells by Graff, R D, Philbert, M A, Lowndes, H E, Reuhl, K R

“…Microtubule (MT) assembly and stability are thought to be dependent on intracellular glutathione for the maintenance of critical sulfhydryl groups. Since…”
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ATP induces Ca(2+) signaling in human chondrons cultured in three-dimensional agarose films by Elfervig, M K, Graff, R D, Lee, G M, Kelley, S S, Sood, A, Banes, A J

“…In vivo, chondrocytes are surrounded by an extracellular matrix, preventing direct cell-to-cell contact. Consequently, intercellular communication through gap…”
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Role of pericellular matrix in development of a mechanically functional neocartilage by Graff, Ronald D., Kelley, Scott S., Lee, Greta M.

“…The role of the chondrocyte pericellular matrix (PCM) was examined in a three‐dimensional chondrocyte culture system to determine whether retention of the…”
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Selective loss of the 180-kDa form of the neural cell adhesion molecule in hippocampus and cerebellum of the adult mouse following trimethyltin administration by Dey, P M, Graff, R D, Lagunowich, L A, Reuhl, K R

“…The neural cell adhesion molecule (NCAM), a membrane glycoprotein which plays critical roles in cell-cell recognition and in the maintenance of…”
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Coordinate Conversion from NAD 27 to NAD 83 by Graff, D R

“…A method for converting North American Datum (NAD) 27 coordinates to NAD 83 coordinates is presented. The method is tested on over 1,000 control points, known…”
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Tissue transglutaminase localization and activity regulation in the extracellular matrix of articular cartilage by Summey, Brett T, Graff, Ronald D, Lai, Thung-Sheng, Greenberg, Charles S, Lee, Greta M

“…Tissue transglutaminase (tTG) catalyzes a Ca 2+-dependent transglutaminase (TGase) activity which cross-links proteins and stabilizes many tissues [C.S…”
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Microtubule dynamics in a cytosolic extract of fetal rat brain by Simon, J R, Graff, R D, Maness, P F

“…Brain microtubule dynamics were studied by video-enhanced differential interference contrast microscopy in a cytosolic extract from fetal rat brain, prepared…”
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Coordinate Conversion from Nad to Nad by Graff, D. R

“…A method for converting North American Datum (NAD) 27 coordinates to NAD 83 coordinates is presented. The method is tested on over 1,000 control points, known…”
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ATP release by mechanically loaded porcine chondrons in pellet culture by Graff, Ronald D., Lazarowski, Eduardo R., Banes, Albert J., Lee, Greta M.

“…Objective To determine whether ATP is released from chondrocytes during mechanical stimulation and whether degradation of ATP generates inorganic pyrophosphate…”
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NCAM Stimulates the Ras-MAPK Pathway and CREB Phosphorylation in Neuronal Cells by Schmid, R-S, Graff, R D, Schaller, MD, Chen, Suzhen, Schachner, M, Hemperly, J J, Maness, P F

“…The neural cell adhesion molecule NCAM plays an important role in axonal growth, learning, and memory. A signaling pathway has been elucidated in which…”
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Annulus cells release ATP in response to vibratory loading in vitro by Yamazaki, Satoru, Weinhold, Paul S., Graff, Ronald D., Tsuzaki, Mari, Kawakami, Mamoru, Minchew, Joe T., Banes, Albert J.

“…Mechanical forces regulate the developmental path and phenotype of a variety of tissues and cultured cells. Vibratory loading as a mechanical stimulus occurs…”
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Extracellular nucleotides, cartilage stress, and calcium crystal formation by Graff, Ronald D, Picher, Maryse, Lee, Greta M

“…Nucleotides are released by chondrocytes at rest and in response to mechanical stimulation. Extracellular nucleotides are metabolized by a variety of…”
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ATP induces Ca2+signaling in human chondrons cultured in three-dimensional agarose films by Elfervig, M.K., Graff, R.D., Lee, G.M., Kelley, S.S., Sood, A., Banes, A.J.

“…ObjectiveIn vivo, chondrocytes are surrounded by an extracellular matrix, preventing direct cell-to-cell contact. Consequently, intercellular communication…”
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Microplate live cell assay system for early events in mechanotransduction by Graff, Ronald D, Lee, Greta M

“…For studying mechanotransduction in cultured cells, we developed a microplate assay using a fluorescence/luminescence plate reader equipped with…”
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Coordinate conversion from NAD27 to NAD83 by GRAFF, D. R

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Development of selective tolerance to interleukin-1β by human chondrocytes in vitro by Lee, Greta M., Tioran, Marianne E., Jansen, Marilyn, Graff, Ronald D., Kelley, Scott S., Lin, Peiyuan

“…Interleukin‐1 induces release of NO and PGE2 and production of matrix degrading enzymes in chondrocytes. In osteoarthritis (OA), IL‐1 continually, or…”
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Efficacy and tolerability of a new formulation of pancrelipase delayed-release capsules in children aged 7 to 11 years with exocrine pancreatic insufficiency and cystic fibrosis: A multicenter, randomized, double-blind, placebo-controlled, two-period crossover, superiority study by Graff, Gavin R., MD, Maguiness, Karen, MS, RD, CSP, McNamara, John, MD, Morton, Ronald, MD, Boyd, David, PharmD, Beckmann, Katrin, MSc, Bennett, Djenane, BSN

“…Abstract Background: Pancreatic enzyme replacement therapy (PERT) is essential for maintaining adequate nutrition in children with exocrine pancreatic…”
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