Search Results - "Graff, MariaElisa"

Genomics of body fat percentage may contribute to sex bias in anorexia nervosa by Hübel, Christopher, Gaspar, Héléna A., Coleman, Jonathan R. I., Finucane, Hilary, Purves, Kirstin L., Hanscombe, Ken B., Prokopenko, Inga, Graff, Mariaelisa, Ngwa, Julius S., Workalemahu, Tsegaselassie, O'Reilly, Paul F., Bulik, Cynthia M., Breen, Gerome

“…Anorexia nervosa (AN) occurs nine times more often in females than in males. Although environmental factors likely play a role, the reasons for this imbalanced…”
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Genetic correlations of psychiatric traits with body composition and glycemic traits are sex- and age-dependent by Hübel, Christopher, Gaspar, Héléna A., Coleman, Jonathan R. I., Hanscombe, Ken B., Purves, Kirstin, Prokopenko, Inga, Graff, Mariaelisa, Ngwa, Julius S., Workalemahu, Tsegaselassie, O’Reilly, Paul F., Bulik, Cynthia M., Breen, Gerome

“…Body composition is often altered in psychiatric disorders. Using genome-wide common genetic variation data, we calculate sex-specific genetic correlations…”
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Influence of alcohol consumption and alcohol metabolism variants on breast cancer risk among Black women: results from the AMBER consortium by Young, Kristin L, Olshan, Andrew F, Lunetta, Kathryn, Graff, Mariaelisa, Williams, Lindsay A, Yao, Song, Zirpoli, Gary R, Troester, Melissa, Palmer, Julie R

“…Moderate to heavy alcohol consumption is associated with an increased risk of breast cancer. The etiologic role of genetic variation in genes involved in…”
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Working to eat: Vulnerability, food insecurity, and obesity among migrant and seasonal farmworker families by Borre, Kristen, Ertle, Luke, Graff, Mariaelisa

“…Background Food insecurity and obesity have potential health consequences for migrant and seasonal farm workers (MSFW). Methods Thirty‐six Latino MSFW working…”
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Strategies for Enriching Variant Coverage in Candidate Disease Loci on a Multiethnic Genotyping Array by Bien, Stephanie A, Wojcik, Genevieve L, Zubair, Niha, Gignoux, Christopher R, Martin, Alicia R, Kocarnik, Jonathan M, Martin, Lisa W, Buyske, Steven, Haessler, Jeffrey, Walker, Ryan W, Cheng, Iona, Graff, Mariaelisa, Xia, Lucy, Franceschini, Nora, Matise, Tara, James, Regina, Hindorff, Lucia, Le Marchand, Loic, North, Kari E, Haiman, Christopher A, Peters, Ulrike, Loos, Ruth J F, Kooperberg, Charles L, Bustamante, Carlos D, Kenny, Eimear E, Carlson, Christopher S

“…Investigating genetic architecture of complex traits in ancestrally diverse populations is imperative to understand the etiology of disease. However, the…”
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Multi-ethnic GWAS and fine-mapping of glycaemic traits identify novel loci in the PAGE Study by Downie, Carolina G., Dimos, Sofia F., Bien, Stephanie A., Hu, Yao, Darst, Burcu F., Polfus, Linda M., Wang, Yujie, Wojcik, Genevieve L., Tao, Ran, Raffield, Laura M., Armstrong, Nicole D., Polikowsky, Hannah G., Below, Jennifer E., Correa, Adolfo, Irvin, Marguerite R., Rasmussen-Torvik, Laura J. F., Carlson, Christopher S., Phillips, Lawrence S., Liu, Simin, Pankow, James S., Rich, Stephen S., Rotter, Jerome I., Buyske, Steven, Matise, Tara C., North, Kari E., Avery, Christy L., Haiman, Christopher A., Loos, Ruth J. F., Kooperberg, Charles, Graff, Mariaelisa, Highland, Heather M.

“…Aims/hypothesis Type 2 diabetes is a growing global public health challenge. Investigating quantitative traits, including fasting glucose, fasting insulin and…”
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Genetic variants affecting bone mineral density and bone mineral content at multiple skeletal sites in Hispanic children by Hou, Ruixue, Cole, Shelley A., Graff, Mariaelisa, Haack, Karin, Laston, Sandra, Comuzzie, Anthony G., Mehta, Nitesh R., Ryan, Kathleen, Cousminer, Diana L., Zemel, Babette S., Grant, Struan F.A., Mitchell, Braxton D., Shypailo, Roman J., Gourlay, Margaret L., North, Kari E., Butte, Nancy F., Voruganti, V. Saroja

“…Osteoporosis is a major public health burden with significant economic costs. However, the correlates of bone health in Hispanic children are understudied. We…”
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Multi-ethnic genome-wide association analyses of white blood cell and platelet traits in the Population Architecture using Genomics and Epidemiology (PAGE) study by Hu, Yao, Bien, Stephanie A, Nishimura, Katherine K, Haessler, Jeffrey, Hodonsky, Chani J, Baldassari, Antoine R, Highland, Heather M, Wang, Zhe, Preuss, Michael, Sitlani, Colleen M, Wojcik, Genevieve L, Tao, Ran, Graff, Mariaelisa, Huckins, Laura M, Sun, Quan, Chen, Ming-Huei, Mousas, Abdou, Auer, Paul L, Lettre, Guillaume, Tang, Weihong, Qi, Lihong, Thyagarajan, Bharat, Buyske, Steve, Fornage, Myriam, Hindorff, Lucia A, Li, Yun, Lin, Danyu, Reiner, Alexander P, North, Kari E, Loos, Ruth J F, Raffield, Laura M, Peters, Ulrike, Avery, Christy L, Kooperberg, Charles

“…Circulating white blood cell and platelet traits are clinically linked to various disease outcomes and differ across individuals and ancestry groups. Genetic…”
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Genetic variants in anti-Müllerian hormone-related genes and breast cancer risk: results from the AMBER consortium by Nichols, Hazel B., Graff, Mariaelisa, Bensen, Jeannette T., Lunetta, Kathryn L., O’Brien, Katie M., Troester, Melissa A., Williams, Lindsay A., Young, Kristin, Hong, Chi-Chen, Yao, Song, Haiman, Christopher A., Ruiz-Narváez, Edward A., Ambrosone, Christine B., Palmer, Julie R., Olshan, Andrew F.

“…Purpose Circulating anti-Müllerian hormone (AMH) levels are positively associated with time to menopause and breast cancer risk. We examined breast cancer…”
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Shared genetic risk between anorexia nervosa and cardiovascular disease events: Evidence from genome‐wide association studies by Qi, Baiyu, Graff, Mariaelisa, Eating Disorders Working Group of the Psychiatric Genomics Consortium, Bulik, Cynthia M, North, Kari E, Munn‐Chernoff, Melissa A

“…Objective Cardiovascular complications occur in up to 80% of patients with anorexia nervosa (AN), yet the underlying mechanisms warrant further investigation…”
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Findings from the Hispanic Community Health Study/Study of Latinos on the Importance of Sociocultural Environmental Interactors: Polygenic Risk Score-by-Immigration and Dietary Interactions by McArdle, Cristin E, Bokhari, Hassan, Rodell, Clinton C, Buchanan, Victoria, Preudhomme, Liana K, Isasi, Carmen R, Graff, Mariaelisa, North, Kari, Gallo, Linda C, Pirzada, Amber, Daviglus, Martha L, Wojcik, Genevieve, Cai, Jianwen, Perreira, Krista, Fernandez-Rhodes, Lindsay

“…Hispanic/Latinos experience a disproportionate burden of obesity. Acculturation to US obesogenic diet and practices may lead to an exacerbation of innate…”
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Correction to: Multi-ethnic genome-wide association analyses of white blood cell and platelet traits in the Population Architecture using Genomics and Epidemiology (PAGE) Study by Hu, Yao, Bien, Stephanie A, Nishimura, Katherine K, Haessler, Jeffrey, Hodonsky, Chani J, Baldassari, Antoine R, Highland, Heather M, Wang, Zhe, Preuss, Michael, Sitlani, Colleen M, Wojcik, Genevieve L, Tao, Ran, Graff, Mariaelisa, Huckins, Laura M, Sun, Quan, Chen, Ming-Huei, Mousas, Abdou, Auer, Paul L, Lettre, Guillaume, Tang, Weihong, Qi, Lihong, Thyagarajan, Bharat, Buyske, Steve, Fornage, Myriam, Hindorff, Lucia A, Li, Yun, Lin, Danyu, Reiner, Alexander P, North, Kari E, Loos, Ruth J. F, Raffield, Laura M, Peters, Ulrike, Avery, Christy L, Kooperberg, Charles

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Genome-wide association study of PR interval in Hispanics/Latinos identifies novel locus at ID2 by Seyerle, Amanda A, Lin, Henry J, Gogarten, Stephanie M, Stilp, Adrienne, Méndez Giráldez, Raul, Soliman, Elsayed, Baldassari, Antoine, Graff, Mariaelisa, Heckbert, Susan, Kerr, Kathleen F, Kooperberg, Charles, Rodriguez, Carlos, Guo, Xiuqing, Yao, Jie, Sotoodehnia, Nona, Taylor, Kent D, Whitsel, Eric A, Rotter, Jerome I, Laurie, Cathy C, Avery, Christy L

“…PR interval (PR) is a heritable electrocardiographic measure of atrial and atrioventricular nodal conduction. Changes in PR duration may be associated with…”
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A survey of microRNA single nucleotide polymorphisms identifies novel breast cancer susceptibility loci in a case-control, population-based study of African-American women by Bensen, Jeannette T, Graff, Mariaelisa, Young, Kristin L, Sethupathy, Praveen, Parker, Joel, Pecot, Chad V, Currin, Kevin, Haddad, Stephen A, Ruiz-Narváez, Edward A, Haiman, Christopher A, Hong, Chi-Chen, Sucheston-Campbell, Lara E, Zhu, Qianqian, Liu, Song, Yao, Song, Bandera, Elisa V, Rosenberg, Lynn, Lunetta, Kathryn L, Ambrosone, Christine B, Palmer, Julie R, Troester, Melissa A, Olshan, Andrew F

“…MicroRNAs (miRNAs) regulate gene expression and influence cancer. Primary transcripts of miRNAs (pri-miRNAs) are poorly annotated and little is known about the…”
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Genetic variants and physical activity interact to affect bone density in Hispanic children by Hou, Ruixue, Cole, Shelley A, Graff, Mariaelisa, Wang, Yujie, Haack, Karin, Laston, Sandra, Mehta, Nitesh R, Shypailo, Roman J, Gourlay, Margaret L, Comuzzie, Anthony G, North, Kari E, Butte, Nancy F, Voruganti, Venkata Saroja

“…Our aim was to investigate if moderate to vigorous physical activity (MVPA), calcium intake interacts with bone mineral density (BMD)-related single nucleotide…”
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Genetics of Chronic Kidney Disease Stages Across Ancestries: The PAGE Study by Lin, Bridget M, Nadkarni, Girish N, Tao, Ran, Graff, Mariaelisa, Fornage, Myriam, Buyske, Steven, Matise, Tara C, Highland, Heather M, Wilkens, Lynne R, Carlson, Christopher S, Park, S Lani, Setiawan, V Wendy, Ambite, Jose Luis, Heiss, Gerardo, Boerwinkle, Eric, Lin, Dan-Yu, Morris, Andrew P, Loos, Ruth J F, Kooperberg, Charles, North, Kari E, Wassel, Christina L, Franceschini, Nora

“…Chronic kidney disease (CKD) is common and disproportionally burdens United States ethnic minorities. Its genetic determinants may differ by disease severity…”
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Multivariable Mendelian randomization with incomplete measurements on the exposure variables in the Hispanic Community Health Study/Study of Latinos by Li, Yilun, Wong, Kin Yau, Howard, Annie Green, Gordon-Larsen, Penny, Highland, Heather M., Graff, Mariaelisa, North, Kari E., Downie, Carolina G., Avery, Christy L., Yu, Bing, Young, Kristin L., Buchanan, Victoria L., Kaplan, Robert, Hou, Lifang, Joyce, Brian Thomas, Qi, Qibin, Sofer, Tamar, Moon, Jee-Young, Lin, Dan-Yu

“…Multivariable Mendelian randomization allows simultaneous estimation of direct causal effects of multiple exposure variables on an outcome. When the exposure…”
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Genetic Determinants of Pelvic Organ Prolapse among African American and Hispanic Women in the Women's Health Initiative by Giri, Ayush, Wu, Jennifer M, Ward, Renee M, Hartmann, Katherine E, Park, Amy J, North, Kari E, Graff, Mariaelisa, Wallace, Robert B, Bareh, Gihan, Qi, Lihong, O'Sullivan, Mary J, Reiner, Alexander P, Edwards, Todd L, Velez Edwards, Digna R

“…Current evidence suggests a multifactorial etiology to pelvic organ prolapse (POP), including genetic predisposition. We conducted a genome-wide association…”
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Genetic pleiotropy underpinning adiposity and inflammation in self-identified Hispanic/Latino populations by Anwar, Mohammad Yaser, Baldassari, Antoine R, Polikowsky, Hannah G, Sitlani, Colleen M, Highland, Heather M, Chami, Nathalie, Chen, Hung-Hsin, Graff, Mariaelisa, Howard, Annie Green, Jung, Su Yon, Petty, Lauren E, Wang, Zhe, Zhu, Wanying, Buyske, Steven, Cheng, Iona, Kaplan, Robert, Kooperberg, Charles, Loos, Ruth J F, Peters, Ulrike, McCormick, Joseph B, Fisher-Hoch, Susan P, Avery, Christy L, Taylor, Kira C, Below, Jennifer E, North, Kari E

“…Concurrent variation in adiposity and inflammation suggests potential shared functional pathways and pleiotropic disease underpinning. Yet, exploration of…”
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Branched chain amino acids harbor distinct and often opposing effects on health and disease by Avery, Christy L., Howard, Annie Green, Lee, Harold H., Downie, Carolina G., Lee, Moa P., Koenigsberg, Sarah H., Ballou, Anna F., Preuss, Michael H., Raffield, Laura M., Yarosh, Rina A., North, Kari E., Gordon-Larsen, Penny, Graff, Mariaelisa

“…Background The branched chain amino acids (BCAA) leucine, isoleucine, and valine are essential nutrients that have been associated with diabetes, cancers, and…”
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