Search Results - "Graff, Ariel"
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Adiposity in schizophrenia: A systematic review and meta‐analysis
Published in Acta psychiatrica Scandinavica (01-12-2021)“…Objective Although a relationship between schizophrenia (SCZ), antipsychotic (AP) medication, and metabolic dysregulation is now well established, the effect…”
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Metformin for the prevention of clozapine‐induced weight gain: A retrospective naturalistic cohort study
Published in Acta psychiatrica Scandinavica (01-09-2022)“…Objective Clozapine is presently the sole antipsychotic with an indication for treatment‐resistant Schizophrenia, but is associated with significant weight…”
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Further in vivo characterization of [11C]‐(+)‐PHNO uptake into a retina‐like region of interest in humans
Published in Synapse (New York, N.Y.) (01-03-2020)“…The neurotransmitter dopamine is present in the retina and is involved in several modulatory functions. Unlike in rodents, dopamine D3 receptors are expressed…”
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The potential role of dopamine D3 receptor neurotransmission in cognition
Published in European neuropsychopharmacology (01-08-2013)“…Abstract Currently available treatments have limited pro-cognitive effects for neuropsychiatric disorders, such as schizophrenia, Parkinson's disease and…”
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Gamma‐aminobutyric acid (GABA) levels in the midcingulate cortex and clozapine response in patients with treatment‐resistant schizophrenia: A proton magnetic resonance spectroscopy (1H‐MRS) study
Published in Psychiatry and clinical neurosciences (01-11-2022)“…Background Gamma‐Aminobutyric Acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system. GABAergic dysfunction has been implicated…”
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Decreased cortical gyrification and surface area in the left medial parietal cortex in patients with treatment‐resistant and ultratreatment‐resistant schizophrenia
Published in Psychiatry and clinical neurosciences (01-01-2023)“…Aim Validating the vulnerabilities and pathologies underlying treatment‐resistant schizophrenia (TRS) is an important challenge in optimizing treatment…”
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Graph theory analysis of the dopamine D2 receptor network in Parkinson’s disease patients with cognitive decline
Published in Journal of neuroscience research (01-03-2021)“…Cognitive decline in Parkinson's disease (PD) is a common sequela of the disorder that has a large impact on patient well‐being. Its physiological etiology,…”
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Measuring amphetamine‐induced dopamine release in humans: A comparative meta‐analysis of [11C]‐raclopride and [11C]‐(+)‐PHNO studies
Published in Synapse (New York, N.Y.) (01-05-2021)“…The radiotracers [11C]‐raclopride and [11C]‐(+)‐PHNO are commonly used to measure differences in amphetamine‐induced dopamine release between healthy persons…”
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Individual determinants of COVID-19 vaccine hesitancy
Published in PloS one (17-11-2021)“…Novel coronavirus disease 2019 (COVID-19) vaccine hesitancy is a barrier to achieving herd immunity, and thus, a prominent public health concern. This study…”
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The relationship between subcortical brain volume and striatal dopamine D2/3 receptor availability in healthy humans assessed with [11C]‐raclopride and [11C]‐(+)‐PHNO PET
Published in Human brain mapping (01-11-2017)“…Background Abnormalities in dopamine (DA) and brain morphology are observed in several neuropsychiatric disorders. However, it is not fully understood how…”
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Kynurenine pathway in depression: A systematic review and meta-analysis
Published in Neuroscience and biobehavioral reviews (01-07-2018)“…•We conducted the first meta-analysis on metabolite levels of kynurenine pathway in patients with depression.•Out of 899 initial records, 22 articles were…”
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Does Family History of Alcohol Use Disorder Relate to Differences in Regional Brain Volumes? A Descriptive Review with New Data
Published in Alcoholism, clinical and experimental research (01-12-2018)“…Background Differences in regional brain volumes as a function of family history (FH) of alcohol use disorder (AUD) have been reported, and it has been…”
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Insight and medication adherence in schizophrenia: An analysis of the CATIE trial
Published in Neuropharmacology (15-05-2020)“…Adherence to antipsychotic medication is critical for the treatment of patients with schizophrenia. Impaired insight into illness is one of the principal…”
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Glutamatergic neurometabolite levels in major depressive disorder: a systematic review and meta-analysis of proton magnetic resonance spectroscopy studies
Published in Molecular psychiatry (01-07-2019)“…Alterations in glutamatergic neurotransmission are implicated in the pathophysiology of depression, and the glutamatergic system represents a treatment target…”
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Effect of electroconvulsive therapy on hippocampal and amygdala volumes: systematic review and meta-analysis
Published in British journal of psychiatry (01-01-2018)“…Electroconvulsive therapy (ECT) is one of the most effective treatments for depression, although the underlying mechanisms remain unclear. Animal studies have…”
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Kynurenic Acid in Schizophrenia: A Systematic Review and Meta-analysis
Published in Schizophrenia bulletin (01-07-2017)“…Kynurenic acid (KYNA) is an endogenous antagonist of N-methyl-D-aspartate and α7 nicotinic acetylcholine receptors that is derived from astrocytes as part of…”
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Treatment-Resistant Schizophrenia: Treatment Response and Resistance in Psychosis (TRRIP) Working Group Consensus Guidelines on Diagnosis and Terminology
Published in The American journal of psychiatry (01-03-2017)“…Objective:Research and clinical translation in schizophrenia is limited by inconsistent definitions of treatment resistance and response. To address this…”
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Structural and functional alterations of the suicidal brain: An updated review of neuroimaging studies
Published in Psychiatry research. Neuroimaging (30-08-2018)“…Brain imaging is a non-invasive and in vivo direct estimation of detailed brain structure, regional brain functioning and estimation of molecular processes in…”
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Tau in Atypical Parkinsonisms: A Meta‐Analysis of in Vivo PET Imaging Findings
Published in Movement disorders clinical practice (Hoboken, N.J.) (01-12-2023)“…Background Progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD) are atypical parkinsonisms (APs) that are classified as tauopathies…”
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Power spectral analysis of resting-state EEG to monitor psychological resilience to stress
Published in Psychiatry Research Communications (01-09-2024)“…Psychological resilience refers to the capacity to adapt and recover from challenging situations, stress, or traumatic events. However, there is currently no…”
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