Search Results - "Graf, Tyler P."

A Scalable Platform for Fabricating Biodegradable Microparticles with Pulsatile Drug Release by Graf, Tyler P., Qiu, Sherry Yue, Varshney, Dhruv, Laracuente, Mei‐Li, Euliano, Erin M., Munnangi, Pujita, Pogostin, Brett H., Baryakova, Tsvetelina, Garyali, Arnav, McHugh, Kevin J.

“…Pulsatile drug delivery systems have the potential to improve patient adherence and therapeutic efficacy by providing a sequence of doses in a single…”
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Intra‐lymph node crosslinking of antigen‐bearing polymers enhances humoral immunity and dendritic cell activation by Euliano, Erin M., Agrawal, Anushka, Yu, Marina H., Graf, Tyler P., Henrich, Emily M., Kunkel, Alyssa A., Hsu, Chia‐Chien, Baryakova, Tsvetelina, McHugh, Kevin J.

“…Lymph node (LN)‐resident dendritic cells (DCs) are a promising target for vaccination given their professional antigen‐presenting capabilities and proximity to…”
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Employing Drug Delivery Strategies to Overcome Challenges Using TLR7/8 Agonists for Cancer Immunotherapy by Varshney, Dhruv, Qiu, Sherry Yue, Graf, Tyler P., McHugh, Kevin J.

“…Toll-like receptors (TLRs) are a potential target for cancer immunotherapy due to their role in the activation of the innate immune system. More specifically,…”
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Fabrication of Pulsatile Polymeric Microparticles Encapsulating Rabies Antigen by Graf, Tyler P, Kadasia, Kadryn, Melhorn, Sarah, Kessler, Eliza, Yang, Haisong, Baryakova, Tsvetelina, Brady, Samantha, McHugh, Kevin J

“…The current guidelines for rabies post-exposure prophylaxis require multiple injections administered over several weeks. This can be disproportionately…”
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A TLR7 Agonist Conjugated to a Nanofibrous Peptide Hydrogel as a Potent Vaccine Adjuvant by Euliano, Erin M, Pogostin, Brett H, Agrawal, Anushka, Yu, Marina H, Baryakova, Tsvetelina H, Graf, Tyler P, Kunkel, Alyssa A, Cahue, Kiana A, Hartgerink, Jeffrey D, McHugh, Kevin J

“…Toll-like receptors (TLRs) recognize pathogen- and damage-associated molecular patterns and, in turn, trigger the release of cytokines and other…”
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Multidomain peptide hydrogel adjuvants elicit strong bias towards humoral immunity by Pogostin, Brett H, Yu, Marina H, Azares, Alon R, Euliano, Erin M, Lai, Cheuk Sun Edwin, Saenz, Gabriel, Wu, Samuel X, Farsheed, Adam C, Melhorn, Sarah M, Graf, Tyler P, Woodside, Darren G, Hartgerink, Jeffrey D, McHugh, Kevin J

“…Adjuvants play a critical role in enhancing vaccine efficacy; however, there is a need to develop new immunomodulatory compounds to address emerging pathogens…”
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Microfluidic Device For Flow-Based Immune Cell Quantification In Whole Blood Using Machine Learning by Dixit, Desh Deepak, Graf, Tyler P., McHugh, Kevin J., Lillehoj, Peter B.

“…This paper presents an innovative approach for flow-based quantification of immune cells in whole blood using microfluidics and machine learning. Target immune…”
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A Scalable Platform for Fabricating Biodegradable Microparticles with Pulsatile Drug Release (Adv. Mater. 22/2023) by Graf, Tyler P., Qiu, Sherry Yue, Varshney, Dhruv, Laracuente, Mei‐Li, Euliano, Erin M., Munnangi, Pujita, Pogostin, Brett H., Baryakova, Tsvetelina, Garyali, Arnav, McHugh, Kevin J.

“…Drug Delivery Systems In article number 2300228, Tyler P. Graf, Kevin J. McHugh, and co‐workers describe the development of an injectable microparticle…”
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