Search Results - "Graf, Thomas"

Historical Origins of Transdifferentiation and Reprogramming by Graf, Thomas

“…Transcription factor-induced reprogramming of specialized cells into other cell types and to pluripotency has revolutionized our thinking about cell…”
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Transcription factors and 3D genome conformation in cell-fate decisions by Stadhouders, Ralph, Filion, Guillaume J., Graf, Thomas

“…How cells adopt different identities has long fascinated biologists. Signal transduction in response to environmental cues results in the activation of…”
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Heat accumulation during pulsed laser materials processing by Weber, Rudolf, Graf, Thomas, Berger, Peter, Onuseit, Volkher, Wiedenmann, Margit, Freitag, Christian, Feuer, Anne

“…Laser materials processing with ultra-short pulses allows very precise and high quality results with a minimum extent of the thermally affected zone. However,…”
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Optimization of the solidification conditions by means of beam oscillation during laser beam welding of aluminum by Hagenlocher, Christian, Sommer, Martin, Fetzer, Florian, Weber, Rudolf, Graf, Thomas

“…Aluminum (AA6016) sheets were welded in overlap configuration to investigate the influence of different beam oscillation patterns on the resulting temperature…”
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Transcription factors orchestrate dynamic interplay between genome topology and gene regulation during cell reprogramming by Stadhouders, Ralph, Vidal, Enrique, Serra, François, Di Stefano, Bruno, Le Dily, François, Quilez, Javier, Gomez, Antonio, Collombet, Samuel, Berenguer, Clara, Cuartero, Yasmina, Hecht, Jochen, Filion, Guillaume J., Beato, Miguel, Marti-Renom, Marc A., Graf, Thomas

“…Chromosomal architecture is known to influence gene expression, yet its role in controlling cell fate remains poorly understood. Reprogramming of somatic cells…”
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Covering the Stem Cell Explosion at the 2017 ISSCR Conference in Boston by Graf, Thomas

“…The meeting covered a plethora of rapidly evolving approaches and areas, such as organoid cultures modeling tissues and organs; stem cell-specific metabolites…”
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The transcription factor code: a beacon for histone methyltransferase docking by Torcal Garcia, Guillem, Graf, Thomas

“…Histone methylation is required for the establishment and maintenance of gene expression patterns that determine cellular identity, and its perturbation often…”
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Cell-of-Origin-Specific 3D Genome Structure Acquired during Somatic Cell Reprogramming by Krijger, Peter Hugo Lodewijk, Di Stefano, Bruno, de Wit, Elzo, Limone, Francesco, van Oevelen, Chris, de Laat, Wouter, Graf, Thomas

“…Forced expression of reprogramming factors can convert somatic cells into induced pluripotent stem cells (iPSCs). Here we studied genome topology dynamics…”
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Differentiation plasticity of hematopoietic cells by Graf, Thomas

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Monotonicity as an effective theory of morphosyntactic variation by Graf, Thomas

“…One of the major goals of linguistics is to delineate the possible range of variation across languages. Recent work has identified a surprising number of…”
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Systemic Human ILC Precursors Provide a Substrate for Tissue ILC Differentiation by Lim, Ai Ing, Li, Yan, Lopez-Lastra, Silvia, Stadhouders, Ralph, Paul, Franziska, Casrouge, Armanda, Serafini, Nicolas, Puel, Anne, Bustamante, Jacinta, Surace, Laura, Masse-Ranson, Guillemette, David, Eyal, Strick-Marchand, Helene, Le Bourhis, Lionel, Cocchi, Roberto, Topazio, Davide, Graziano, Paolo, Muscarella, Lucia Anna, Rogge, Lars, Norel, Xavier, Sallenave, Jean-Michel, Allez, Matthieu, Graf, Thomas, Hendriks, Rudi W., Casanova, Jean-Laurent, Amit, Ido, Yssel, Hans, Di Santo, James P.

“…Innate lymphoid cells (ILCs) represent innate versions of T helper and cytotoxic T cells that differentiate from committed ILC precursors (ILCPs). How ILCPs…”
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Self-Shielding of X-ray Emission from Ultrafast Laser Processing Due to Geometrical Changes of the Interaction Zone by Holland, Julian, Hagenlocher, Christian, Weber, Rudolf, Graf, Thomas

“…Materials processing with ultrashort laser pulses is one of the most important approaches when it comes to machining with very high accuracy. High pulse…”
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Process Window for Highly Efficient Laser-Based Powder Bed Fusion of AlSi10Mg with Reduced Pore Formation by Leis, Artur, Weber, Rudolf, Graf, Thomas

“…The process window for highly efficient laser-based powder bed fusion (LPBF), ensuring the production of parts with low porosity, was determined by analyzing…”
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Transcription Factors Drive Tet2-Mediated Enhancer Demethylation to Reprogram Cell Fate by Sardina, Jose Luis, Collombet, Samuel, Tian, Tian V., Gómez, Antonio, Di Stefano, Bruno, Berenguer, Clara, Brumbaugh, Justin, Stadhouders, Ralph, Segura-Morales, Carolina, Gut, Marta, Gut, Ivo G., Heath, Simon, Aranda, Sergi, Di Croce, Luciano, Hochedlinger, Konrad, Thieffry, Denis, Graf, Thomas

“…Here, we report DNA methylation and hydroxymethylation dynamics at nucleotide resolution using C/EBPα-enhanced reprogramming of B cells into induced…”
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Scaling the productivity of laser structuring processes using picosecond laser pulses at average powers of up to 420 W to produce superhydrophobic surfaces on stainless steel AISI 316L by Faas, Sebastian, Bielke, Uwe, Weber, Rudolf, Graf, Thomas

“…We investigate the approach to scale up the productivity of the laser-based generation of superhydrophobic surfaces by means of increased average laser powers…”
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Explicit analytical expressions for the influence of welding parameters on the grain structure of laser beam welds in aluminium alloys by Hagenlocher, Christian, Fetzer, Florian, Weller, Daniel, Weber, Rudolf, Graf, Thomas

“…An explicit analytical model to express the influence of the welding parameters on the grain structure that is formed in laser beam welds in aluminium alloys…”
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Influence of Pulse Duration on X-ray Emission during Industrial Ultrafast Laser Processing by Holland, Julian, Weber, Rudolf, Sailer, Marc, Graf, Thomas

“…Soft X-ray emissions during the processing of industrial materials with ultrafast lasers are of major interest, especially against the background of legal…”
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Moving pharma contracting into the era of accountability by Graf, Thomas R

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Impact of topography on groundwater salinization due to ocean surge inundation by Yu, Xuan, Yang, Jie, Graf, Thomas, Koneshloo, Mohammad, O'Neal, Michael A., Michael, Holly A.

“…Sea‐level rise and increases in the frequency and intensity of ocean surges caused by climate change are likely to exacerbate adverse effects on low‐lying…”
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Image processing based detection of the fibre orientation during depth-controlled laser ablation of CFRP monitored by optical coherence tomography by Holder, Daniel, Buser, Matthias, Boley, Steffen, Weber, Rudolf, Graf, Thomas

“…Layer-accurate and precisely stepped removal of damaged areas is required for the repairing process of parts made of carbon fibre-reinforced plastic (CFRP) to…”
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