Search Results - "Graf, P."

Bleach Activates a Redox-Regulated Chaperone by Oxidative Protein Unfolding by Winter, J., Ilbert, M., Graf, P.C.F., Özcelik, D., Jakob, U.

“…Hypochlorous acid (HOCl), the active ingredient in household bleach, is an effective antimicrobial produced by the mammalian host defense to kill invading…”
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Clinical Utility of the Nuclear-localized AR-V7 Biomarker in Circulating Tumor Cells in Improving Physician Treatment Choice in Castration-resistant Prostate Cancer by Graf, Ryon P., Hullings, Melanie, Barnett, Ethan S., Carbone, Emily, Dittamore, Ryan, Scher, Howard I.

“…Proof of the clinical utility of a biomarker is when its use informs a management decision and improves patient outcomes relative to when it is not used. To…”
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Isolated during adolescence: long-term impact on social behavior, pain sensitivity, and the oxytocin system in male and female rats by P Graf, Akseli, Hansson, Anita C, Spanagel, Rainer

“…Adolescent social isolation (ASI) has profound long-term effects on behavioral and neural development. Despite this, the specific long-term impact of ASI…”
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Assessment of the Validity of Nuclear-Localized Androgen Receptor Splice Variant 7 in Circulating Tumor Cells as a Predictive Biomarker for Castration-Resistant Prostate Cancer by Scher, Howard I, Graf, Ryon P, Schreiber, Nicole A, Jayaram, Anuradha, Winquist, Eric, McLaughlin, Brigit, Lu, David, Fleisher, Martin, Orr, Sarah, Lowes, Lori, Anderson, Amanda, Wang, Yipeng, Dittamore, Ryan, Allan, Alison L, Attard, Gerhardt, Heller, Glenn

“…A blood test to determine whether to treat patients with metastatic castration-resistant prostate cancer (mCRPC) with an androgen receptor signaling (ARS)…”
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The Initial Detection and Partial Characterization of Circulating Tumor Cells in Neuroendocrine Prostate Cancer by Beltran, Himisha, Jendrisak, Adam, Landers, Mark, Mosquera, Juan Miguel, Kossai, Myriam, Louw, Jessica, Krupa, Rachel, Graf, Ryon P, Schreiber, Nicole A, Nanus, David M, Tagawa, Scott T, Marrinucci, Dena, Dittamore, Ryan, Scher, Howard I

“…The transition of prostate adenocarcinoma to a predominantly androgen receptor (AR) signaling independent phenotype can occur in the later stages of the…”
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Prognostic significance of low volume sentinel lymph node disease in early-stage cervical cancer by Cibula, D, Abu-Rustum, N.R, Dusek, L, Zikán, M, Zaal, A, Sevcik, L, Kenter, G.G, Querleu, D, Jach, R, Bats, A.S, Dyduch, G, Graf, P, Klat, J, Lacheta, J, Meijer, C.J.L.M, Mery, E, Verheijen, R, Zweemer, R.P

“…Abstract Objective Evaluate prognostic significance of low volume disease detected in sentinel nodes (SN) of patients with early stages cervical cancer…”
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A Scalable Platform for Fabricating Biodegradable Microparticles with Pulsatile Drug Release by Graf, Tyler P., Qiu, Sherry Yue, Varshney, Dhruv, Laracuente, Mei‐Li, Euliano, Erin M., Munnangi, Pujita, Pogostin, Brett H., Baryakova, Tsvetelina, Garyali, Arnav, McHugh, Kevin J.

“…Pulsatile drug delivery systems have the potential to improve patient adherence and therapeutic efficacy by providing a sequence of doses in a single…”
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Chromosomal Instability Estimation Based on Next Generation Sequencing and Single Cell Genome Wide Copy Number Variation Analysis by Greene, Stephanie B, Dago, Angel E, Leitz, Laura J, Wang, Yipeng, Lee, Jerry, Werner, Shannon L, Gendreau, Steven, Patel, Premal, Jia, Shidong, Zhang, Liangxuan, Tucker, Eric K, Malchiodi, Michael, Graf, Ryon P, Dittamore, Ryan, Marrinucci, Dena, Landers, Mark

“…Genomic instability is a hallmark of cancer often associated with poor patient outcome and resistance to targeted therapy. Assessment of genomic instability in…”
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Endogenous oxytocin, cortisol, and testosterone in response to group singing by Bowling, D.L., Gahr, J., Ancochea, P. Graf, Hoeschele, M., Canoine, V., Fusani, L., Fitch, W.T.

“…Humans have sung together for thousands of years. Today, regular participation in group singing is associated with benefits across psychological and biological…”
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New insights in reactivity of hydroxyl groups in water gas shift reaction on Pt/ZrO2 by GRAF, P. O, DE VLIEGER, D. J. M, MOJET, B. L, LEFFERTS, L

“…The reactivity of mono- and multi-coordinated hydroxyl groups on Pt/ZrO2 with CO was investigated with in-situ transmission FT-IR. It was found that…”
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Androgen receptor expression on circulating tumor cells in metastatic breast cancer by Fujii, Takeo, Reuben, James M, Huo, Lei, Espinosa Fernandez, Jose Rodrigo, Gong, Yun, Krupa, Rachel, Suraneni, Mahipal V, Graf, Ryon P, Lee, Jerry, Greene, Stephanie, Rodriguez, Angel, Dugan, Lyndsey, Louw, Jessica, Lim, Bora, Barcenas, Carlos H, Marx, Angela N, Tripathy, Debu, Wang, Yipeng, Landers, Mark, Dittamore, Ryan, Ueno, Naoto T

“…Androgen receptor (AR) is frequently detected in breast cancers, and AR-targeted therapies are showing activity in AR-positive (AR+) breast cancer. However,…”
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Comparison of PD-L1 tumor cell expression with 22C3, 28-8, and SP142 IHC assays across multiple tumor types by Maule, Jake G, Clinton, Lani K, Graf, Ryon P, Xiao, Jinpeng, Oxnard, Geoffrey R, Ross, Jeffrey S, Huang, Richard S P

“…BackgroundMultiple PD-L1 immunohistochemistry (IHC) assays, including DAKO 22C3, DAKO 28-8, and Ventana SP142 PD-L1 IHC assays, have been approved by the Food…”
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Durable responders in advanced NSCLC with elevated TMB and treated with 1L immune checkpoint inhibitor: a real-world outcomes analysis by Huang, Richard S P, Carbone, David P, Li, Gerald, Schrock, Alexa, Graf, Ryon P, Zhang, Liangliang, Murugesan, Karthikeyan, Ross, Jeffrey S, Tolba, Khaled, Sands, Jacob, Oxnard, Geoffrey R, Spigel, David

“…BackgroundFor patients with advanced non-small cell lung carcinoma (NSCLC), immune checkpoint inhibitor (ICPI) and chemotherapy (chemo) ICPI represent two…”
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Mobile-bearing versus fixed-bearing total knee implants. Results of a series of 100 randomised cases after 9 years follow-up by Poirier, N, Graf, P, Dubrana, F

“…Abstract Hypothesis Mobile-bearing total knee arthroplasty (TKA) implants were developed as an alternative to fixed-bearing implants because of their…”
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Intra‐lymph node crosslinking of antigen‐bearing polymers enhances humoral immunity and dendritic cell activation by Euliano, Erin M., Agrawal, Anushka, Yu, Marina H., Graf, Tyler P., Henrich, Emily M., Kunkel, Alyssa A., Hsu, Chia‐Chien, Baryakova, Tsvetelina, McHugh, Kevin J.

“…Lymph node (LN)‐resident dendritic cells (DCs) are a promising target for vaccination given their professional antigen‐presenting capabilities and proximity to…”
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Complementary Roles for Tissue- and Blood-Based Comprehensive Genomic Profiling for Detection of Actionable Driver Alterations in Advanced NSCLC by Schwartzberg, Lee S., Li, Gerald, Tolba, Khaled, Bourla, Ariel B., Schulze, Katja, Gadgil, Rujuta, Fine, Alexander, Lofgren, Katherine T., Graf, Ryon P., Oxnard, Geoffrey R., Daniel, Davey

“…Whereas tumor biopsy is the reference standard for genomic profiling of advanced NSCLC, there are now multiple assays approved by the Food and Drug…”
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Radiographic outcomes in the coronal plane with iASSIST™ versus optical navigation for total knee arthroplasty: A preliminary case-control study by Desseaux, A, Graf, P, Dubrana, F, Marino, R, Clavé, A

“…Abstract Background The new navigation system iASSIST™ for total knee arthroplasty (TKA) relies on accelerometers and gyroscopes. The objective of this…”
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General Assembly, Research Caveats: Proceedings of International Consensus on Orthopedic Infections by Bargon, R., Bruenke, J., Carli, Alberto, Fabritius, M., Goel, Rahul, Goswami, Karan, Graf, P., Groff, Hannah, Grupp, Thomas, Malchau, Henrik, Mohaddes, Maziar, Novaes de Santana, Camila, Phillips, K. Scott, Rohde, Holger, Rolfson, Ola, Rondon, Alexander, Schaer, Thomas, Sculco, Peter, Svensson, Karin

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Equine behaviour and heart rate in temperament tests with or without rider or handler by König von Borstel, U, Euent, S, Graf, P, König, S, Gauly, M

“…Abstract The aim of the present study was to compare horses' heart rate (HR), heart rate variability (RMSSD, pNN50) and behaviour in the same temperament test…”
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Short-term effects of tagging on activity and movement patterns of Eurasian beavers (Castor fiber) by Graf, P. M., Hochreiter, J., Hackländer, K., Wilson, R. P., Rosell, F.

“…Bio-logging is becoming increasingly popular amongst wildlife researchers, providing a remote way of monitoring free-ranging animals in their natural habitats…”
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