Search Results - "Graf, Nathan J"

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  1. 1

    A pro-cathepsin L mutant is a luminal substrate for endoplasmic-reticulum-associated degradation in C. elegans by Miedel, Mark T, Graf, Nathan J, Stephen, Kate E, Long, Olivia S, Pak, Stephen C, Perlmutter, David H, Silverman, Gary A, Luke, Cliff J

    Published in PloS one (02-07-2012)
    “…Endoplasmic-reticulum associated degradation (ERAD) is a major cellular misfolded protein disposal pathway that is well conserved from yeast to mammals. In…”
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  2. 2

    Using C. elegans to identify the protease targets of serpins in vivo by Bhatia, Sangeeta R, Miedel, Mark T, Chotoo, Cavita K, Graf, Nathan J, Hood, Brian L, Conrads, Thomas P, Silverman, Gary A, Luke, Cliff J

    Published in Methods in enzymology (2011)
    “…Most serpins inhibit serine and/or cysteine proteases, and their inhibitory activities are usually defined in vitro. However, the physiological protease…”
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