Search Results - "Graf, Nathan J"
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A pro-cathepsin L mutant is a luminal substrate for endoplasmic-reticulum-associated degradation in C. elegans
Published in PloS one (02-07-2012)“…Endoplasmic-reticulum associated degradation (ERAD) is a major cellular misfolded protein disposal pathway that is well conserved from yeast to mammals. In…”
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Using C. elegans to identify the protease targets of serpins in vivo
Published in Methods in enzymology (2011)“…Most serpins inhibit serine and/or cysteine proteases, and their inhibitory activities are usually defined in vitro. However, the physiological protease…”
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Journal Article