Search Results - "Graf, Friedrich"

Nivolumab Exposure-Response Analyses of Efficacy and Safety in Previously Treated Squamous or Nonsquamous Non-Small Cell Lung Cancer by Feng, Yan, Wang, Xiaoning, Bajaj, Gaurav, Agrawal, Shruti, Bello, Akintunde, Lestini, Brian, Finckenstein, Friedrich Graf, Park, Jong-Soon, Roy, Amit

“…Nivolumab is a fully human IgG4 monoclonal antiprogrammed death-1 antibody with demonstrated efficacy, including durable responses and prolonged survival, in…”
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Lifileucel, a Tumor-Infiltrating Lymphocyte Therapy, in Metastatic Melanoma by Sarnaik, Amod A, Hamid, Omid, Khushalani, Nikhil I, Lewis, Karl D, Medina, Theresa, Kluger, Harriet M, Thomas, Sajeve S, Domingo-Musibay, Evidio, Pavlick, Anna C, Whitman, Eric D, Martin-Algarra, Salvador, Corrie, Pippa, Curti, Brendan D, Oláh, Judit, Lutzky, Jose, Weber, Jeffrey S, Larkin, James M G, Shi, Wen, Takamura, Toshimi, Jagasia, Madan, Qin, Harry, Wu, Xiao, Chartier, Cecile, Graf Finckenstein, Friedrich, Fardis, Maria, Kirkwood, John M, Chesney, Jason A

“…Effective treatment options are limited for patients with advanced (metastatic or unresectable) melanoma who progress after immune checkpoint inhibitors and…”
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Efficacy and safety of lifileucel, a one-time autologous tumor-infiltrating lymphocyte (TIL) cell therapy, in patients with advanced melanoma after progression on immune checkpoint inhibitors and targeted therapies: pooled analysis of consecutive cohorts of the C-144-01 study by Chesney, Jason, Lewis, Karl D, Kluger, Harriet, Hamid, Omid, Whitman, Eric, Thomas, Sajeve, Wermke, Martin, Cusnir, Mike, Domingo-Musibay, Evidio, Phan, Giao Q, Kirkwood, John M, Hassel, Jessica C, Orloff, Marlana, Larkin, James, Weber, Jeffrey, Furness, Andrew J S, Khushalani, Nikhil I, Medina, Theresa, Egger, Michael E, Graf Finckenstein, Friedrich, Jagasia, Madan, Hari, Parameswaran, Sulur, Giri, Shi, Wen, Wu, Xiao, Sarnaik, Amod

“…Patients with advanced melanoma have limited treatment options after progression on immune checkpoint inhibitors (ICI). Lifileucel, a one-time autologous…”
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Anglo-Saxon Studies in Heidelberg: Georg Jellinek, Max Weber and Ernst Troeltsch by Graf, Friedrich Wilhelm

“…In the German Kaiserreich the University of Heidelberg was known as a liberal academic institution, with internationally well-known professors and many…”
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Identification of a PAX-FKHR gene expression signature that defines molecular classes and determines the prognosis of alveolar rhabdomyosarcomas by DAVICIONI, Elai, FINCKENSTEIN, Friedrich Graf, SHAHBAZIAN, Violette, BUCKLEY, Jonathan D, TRICHE, Timothy J, ANDERSON, Michael J

“…Alveolar rhabdomyosarcomas (ARMS) are aggressive soft-tissue sarcomas affecting children and young adults. Most ARMS tumors express the PAX3-FKHR or PAX7-FKHR…”
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Lifileucel, an Autologous Tumor-Infiltrating Lymphocyte Monotherapy, in Patients with Advanced Non-Small Cell Lung Cancer Resistant to Immune Checkpoint Inhibitors by Schoenfeld, Adam J, Lee, Sylvia M, Doger de Spéville, Bernard, Gettinger, Scott N, Häfliger, Simon, Sukari, Ammar, Papa, Sophie, Rodríguez-Moreno, Juan F, Graf Finckenstein, Friedrich, Fiaz, Rana, Catlett, Melissa, Chen, Guang, Qi, Rongsu, Masteller, Emma L, Gontcharova, Viktoria, He, Kai

“…In this phase 2 multicenter study, we evaluated the efficacy and safety of lifileucel (LN-145), an autologous tumor-infiltrating lymphocyte cell therapy, in…”
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776 Long-term efficacy and safety of lifileucel tumor-infiltrating lymphocyte (TIL) cell therapy in patients with advanced melanoma: a 4-year analysis of the C-144–01 study by Medina, Theresa, Chesney, Jason A, Whitman, Eric, Kluger, Harriet, Thomas, Sajeve, Sarnaik, Amod A, Kirkwood, John M, Larkin, James, Weber, Jeffrey, Hamid, Omid, Wermke, Martin, Finckenstein, Friedrich Graf, Chou, Jeffrey, Gastman, Brian, Sulur, Giri, Wu, Xiao, Shi, Wen, Domingo-Musibay, Evidio

“…BackgroundImmune checkpoint inhibitors (ICI) have improved outcomes for patients with metastatic melanoma; nevertheless, resistance is common and subsequent…”
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778 TILVANCE-301, a phase 3 study of lifileucel tumor-infiltrating lymphocyte (TIL) cell therapy combined with pembrolizumab (pembro) vs pembro alone in treatment-naïve unresectable or metastatic melanoma by Olson, Daniel J, Larkin, James, Hong, Young, Thomas, Sajeve, Martin-Liberal, Juan, Furness, Andrew JS, Terheyden, Patrick, In, Gino K, Poklepovic, Andrew S, Samhouri, Yazan, Lammers, Philip, Atkinson, Victoria, Nguyen, Ryan H, Peretz, Idit, Butler, Marcus, Finckenstein, Friedrich Graf, Chou, Jeffrey, Wu, Xiao, Sulur, Giri, Shi, Wen, Haanen, John B

“…BackgroundNovel early-line therapies for advanced (unresectable or metastatic) melanoma are needed to improve the rate of deep and durable responses and…”
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Molecular Classification of Rhabdomyosarcoma--Genotypic and Phenotypic Determinants of Diagnosis: A Report from the Children's Oncology Group by Davicioni, Elai, Anderson, Michael J, Finckenstein, Friedrich Graf, Lynch, James C, Qualman, Stephen J, Shimada, Hiroyuki, Schofield, Deborah E, Buckley, Jonathan D, Meyer, William H, Sorensen, Poul H.B, Triche, Timothy J

“…Rhabdomyosarcoma (RMS) in children occurs as two major histological subtypes, embryonal (ERMS) and alveolar (ARMS). ERMS is associated with an 11p15.5 loss of…”
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Differential Mechanisms of Acquired Resistance to Insulin-like Growth Factor-I Receptor Antibody Therapy or to a Small-Molecule Inhibitor, BMS-754807, in a Human Rhabdomyosarcoma Model by FEI HUANG, HURLBURT, Warren, GREER, Ann, REEVES, Karen A, HILLERMAN, Stephen, HAN CHANG, FARGNOLI, Joseph, GRAF FINCKENSTEIN, Friedrich, GOTTARDIS, Marco M, CARBONI, Joan M

“…Agents targeting insulin-like growth factor-I receptor (IGF-IR), including antibodies and small-molecule inhibitors, are currently in clinical development for…”
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Dual IGF-1R/InsR Inhibitor BMS-754807 Synergizes with Hormonal Agents in Treatment of Estrogen-Dependent Breast Cancer by XIAONAN HOU, FEI HUANG, HALUSKA, Paul, MACEDO, Luciana F, HARRINGTON, Sean C, REEVES, Karen A, GREER, Ann, GRAF FINCKENSTEIN, Friedrich, BRODIE, Angela, GOTTARDIS, Marco M, CARBONI, Joan M

“…Insulin-like growth factor (IGF) signaling has been implicated in the resistance to hormonal therapy in breast cancer. Using a model of postmenopausal,…”
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The controversial universality of individual human rights by Graf, Friedrich Wilhelm

“…Human rights is currently a very relevant but also very controversial issue in international politics in the aftermath of some of the events that occurred…”
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Molecular Classification of Rhabdomyosarcoma—Genotypic and Phenotypic Determinants of Diagnosis by Davicioni, Elai, Anderson, Michael J, Finckenstein, Friedrich Graf, Lynch, James C, Qualman, Stephen J, Shimada, Hiroyuki, Schofield, Deborah E, Buckley, Jonathan D, Meyer, William H, Sorensen, Poul H.B, Triche, Timothy J

“…Rhabdomyosarcoma (RMS) in children occurs as two major histological subtypes, embryonal (ERMS) and alveolar (ARMS). ERMS is associated with an 11p15.5 loss of…”
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Abstract P050: Trial in progress: A phase 2 multicenter study of autologous tumor-infiltrating lymphocyte (TIL, LN-145) cell therapy in patients with metastatic non-small cell lung cancer (mNSCLC) by Massarelli, Erminia, Samakoglu, Selda, Gontcharova, Viktoria, Chen, Guang, Jagasia, Madan, Finckenstein, Friedrich Graf, Sukari, Ammar

“…Patients with mNSCLC without actionable driver mutation(s) who have progressed after cytotoxic chemotherapy plus immune checkpoint inhibitors (ICI) ±…”
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COUR DE JUSTICE DE L'UNION EUROPÉENNE: THOUGHTS ON THE PRESENT CHALLENGES OF EUROPEAN LAW by VON WESTPHALEN, FRIEDRICH GRAF

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Abstract CT246: A phase 2 multicenter study of autologous tumor infiltrating lymphocytes (TIL, LN-145) cell therapy in patients with metastatic non-small cell lung cancer (mNSCLC) by Massarelli, Erminia, Goldberg, Zelanna, Cacovean, Alex, Yadav, Bhagyashree, Chen, Guang, Jagasia, Madan, Finckenstein, Friedrich Graf, Fardis, Maria, Sukari, Ammar

“…Background Patients with mNSCLC without actionable driver mutation(s) who have progressed after cytotoxic chemotherapy plus immune checkpoint inhibitors (ICI)…”
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THOUGHTS ON THE PRESENT CHALLENGES OF EUROPEAN LAW by Von Westphalen, Friedrich Graf

“…[...]this article will also touch on some legal-political issues relevant to Brexit. The preliminary implementation of CETA would, however, depend on a…”
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Thoughts on the present challenges of European law: Cour de Justice de l'Union Europeenne by Von Westphalen, Friedrich Graf

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Abstract CT244: A Phase 1/2 study evaluating the safety and efficacy of IOV-2001 in patients with relapsed or refractory chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) by Long, Meixiao, Woyach, Jennifer, Pinilla-Ibarz, Javier, Stephens, Deborah M., Cacovean, Alex, Fiaz, Rana, Goldberg, Zelanna, Jagasia, Madan, Finckenstein, Friedrich Graf, Fardis, Maria, Byrd, John C.

“…Background While Bruton's Tyrosine Kinase (BTK) inhibitors approved for CLL/SLL (ibrutinib, acalabrutinib) can mediate durable responses in some patients,…”
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Ernst Troeltsch's Evaluation of Max and Alfred Weber: Introduction and Translation of a Letter by Ernst Troeltsch to Heinrich Dietzel by Graf, Friedrich Wilhelm

“…Discusses Ernst Troeltsch's appraisal of Max & Alfred Weber. Troeltsch was a colleague & friend of Max Weber & the two families shared living quarters in…”
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