Search Results - "Graf, Erika"
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Whole-brain irradiation with hippocampal sparing and dose escalation on metastases: neurocognitive testing and biological imaging (HIPPORAD) - a phase II prospective randomized multicenter trial (NOA-14, ARO 2015-3, DKTK-ROG)
Published in BMC cancer (08-06-2020)“…Whole brain radiation therapy (WBRT) is the standard therapy for multiple brain metastases. However, WBRT has a poor local tumor control and is associated with…”
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Cytokine adsorption in patients with acute-on-chronic liver failure (CYTOHEP)-a single center, open-label, three-arm, randomized, controlled intervention trial
Published in Current controlled trials in cardiovascular medicine (18-03-2022)“…Liver cirrhosis is a major healthcare problem and the mortality rate is high. During recent years, systemic inflammation has been recognized as a major driver…”
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Assessing the effect of a regional integrated care model over ten years using quality indicators based on claims data - the basic statistical methodology of the INTEGRAL project
Published in BMC health services research (24-02-2022)“…The regional integrated health care model "Healthy Kinzigtal" started in 2006 with the goal of optimizing health care and economic efficiency. The INTEGRAL…”
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An online program with individualized vs automated support for significant others of depressed individuals – study protocol of a randomized controlled trial
Published in BMC psychiatry (28-07-2022)“…Abstract Background Due to budget restrictions in mental health care, non-professional caregivers are increasingly burdened with the emotional and practical…”
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Primary dementia care based on the individual needs of the patient: study protocol of the cluster randomized controlled trial, DemStepCare
Published in BMC geriatrics (01-04-2021)“…Most people with dementia (PwD) are cared for at home, with general practitioners (GPs) playing a key part in the treatment. However, primary dementia care…”
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Vector selection of a quadripolar left ventricular pacing lead affects acute hemodynamic response to cardiac resynchronization therapy: a randomized cross-over trial
Published in PloS one (24-06-2013)“…A suboptimal left ventricular (LV) pacing site may account for non-responsiveness of patients to cardiac resynchronization therapy (CRT). The vector selection…”
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Assessment and comparison of prognostic classification schemes for survival data
Published in Statistics in medicine (15-09-1999)“…Prognostic classification schemes have often been used in medical applications, but rarely subjected to a rigorous examination of their adequacy. For survival…”
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BCNU for recurrent glioblastoma multiforme: efficacy, toxicity and prognostic factors
Published in BMC cancer (02-02-2010)“…The prognosis for patients with recurrent glioblastoma is still poor with a median survival between 3 and 6 months. Reports about the application of carmustine…”
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GREAT—a randomized controlled trial comparing HydroSoft/HydroFrame and bare platinum coils for endovascular aneurysm treatment: procedural safety and core-lab-assessedangiographic results
Published in Neuroradiology (01-08-2016)“…Introduction Hybrid hydrogel-platinum coils (HydroCoil) have proven effective for endovascular aneurysm treatment. To overcome technical limitations (coil…”
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Patient-related benefits of amyloid PET imaging in dementia: Rationale and design of the German randomized coverage with evidence development study ENABLE
Published in Alzheimer's & dementia : translational research & clinical interventions (01-07-2023)“…The utility of amyloid positron emission tomography (PET) for the etiological diagnosis of dementia and its impact on functional status of patients in routine…”
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Systemic immune modulation by stereotactic radiotherapy in early-stage lung cancer
Published in NPJ precision oncology (02-03-2023)“…We performed a prospective study of circulating immune cell changes after stereotactic body radiotherapy (SBRT) in 50 early-stage NSCLC patients. We found no…”
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The effect of methylphenidate intake on brain structure in adults with ADHD in a placebo-controlled randomized trial
Published in Journal of psychiatry & neuroscience (01-11-2016)“…Background Based on animal research several authors have warned that the application of methylphenidate, the first-line drug for the treatment of…”
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Non-ulcerated necrotizing sialometaplasia may mimic a salivary gland tumor
Published in Autopsy & case reports (2021)“…Necrotizing sialometaplasia (NS) is a benign, self-limiting inflammatory entity that mainly affects the minor salivary glands located in the hard palate…”
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Design of a placebo-controlled, randomized study of the efficacy of repetitive transcranial magnetic stimulation for the treatment of chronic tinntius
Published in BMC psychiatry (15-04-2008)“…Background Chronic tinnitus is a frequent condition, which can have enormous impact on patient's life and which is very difficult to treat. Accumulating data…”
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Dose-Dense Doxorubicin, Docetaxel, and Granulocyte Colony-Stimulating Factor Support With or Without Tamoxifen as Preoperative Therapy in Patients With Operable Carcinoma of the Breast: A Randomized, Controlled, Open Phase IIb Study
Published in Journal of clinical oncology (01-08-2001)“…To investigate the effect of adding tamoxifen to a preoperative dose-dense doxorubicin and docetaxel regimen on the pathologic response of primary operable…”
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Tamoxifen Versus Control After Adjuvant, Risk-Adapted Chemotherapy in Postmenopausal, Receptor-Negative Patients With Breast Cancer: A Randomized Trial (GABG-IV D-93)—The German Adjuvant Breast Cancer Group
Published in Journal of clinical oncology (01-11-2005)“…To investigate the effect of adjuvant sequential tamoxifen after chemotherapy in postmenopausal patients with hormone receptor-negative breast cancer. Patients…”
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Cytokine adsorption in patients with severe COVID-19 pneumonia requiring extracorporeal membrane oxygenation (CYCOV): a single centre, open-label, randomised, controlled trial
Published in The lancet respiratory medicine (01-07-2021)“…We sought to clarify the benefit of cytokine adsorption in patients with COVID-19 supported with venovenous extracorporeal membrane oxygenation (ECMO). We did…”
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Comparison of complex modeling strategies for prediction of a binary outcome based on a few, highly correlated predictors
Published in Biometrical journal (01-05-2020)“…Motivated by a clinical prediction problem, a simulation study was performed to compare different approaches for building risk prediction models. Robust…”
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