Search Results - "Graf, BM"

Local anesthetic myotoxicity by Zink, Wolfgang, Graf, Bernhard M

“…Skeletal muscle toxicity is a rare and uncommon side effect of local anesthetic drugs. Intramuscular injections of these agents regularly result in reversible…”
Get full text

The Acute Myotoxic Effects of Bupivacaine and Ropivacaine After Continuous Peripheral Nerve Blockades by Zink, Wolfgang, Seif, Christoph, Bohl, Jürgen R. E., Hacke, Nicola, Braun, Peter M., Sinner, Barbara, Martin, Eike, Fink, Rainer H. A., Graf, Bernhard M.

“…Bupivacaine causes muscle damage. However, the myotoxic potency of ropivacaine is still unexplored. Therefore, we performed this study to compare the effects…”
Get full text

Stereospecific effect of bupivacaine isomers on atrioventricular conduction in the isolated perfused guinea pig heart by GRAF, B. M, MARTIN, E, BOSNJAK, Z. J, STOWE, D. F

“…The local anesthetic bupivacaine is an equal mixture of two optically active isomers known to exert different cardiotoxic profiles in vivo. Enantiomer-specific…”
Get full text

Nociceptive Flexion Reflex Threshold is No Suitable Marker for Diagnosing Opioid-Induced Hyperalgesia by Trübenbacher, Luisa, Lindenberg, Nicole, Graf, Bernhard M, Backmund, Markus, Unglaub, Wilhelm, Lassen, Christoph L

“…Opioid induced hyperalgesia (OIH) describes a state of altered pain sensation due to opioid exposure. It often occurs among persons with opioid use disorder…”
Get full text

Lipid Rescue Reverses the Bupivacaine-induced Block of the Fast Na+ Current (INa) in Cardiomyocytes of the Rat Left Ventricle by Wagner, Michael, Zausig, York A, Ruf, Stefan, Rudakova, Elena, Gruber, Michael, Graf, Bernhard M, Volk, Tilmann

“…BACKGROUND:Cardiovascular resuscitation upon intoxication with lipophilic ion channel–blocking agents has proven most difficult. Recently, favorable results…”
Get full text

The Comparative Effects of Equimolar Sevoflurane and Isoflurane in Isolated Hearts by Graf, Bernhard M., Vicenzi, Martin N., Bosnjak, Zeljko J., Stowe, David F.

“…The aim of this study was to compare the direct effects of equivalent molar concentrations of sevoflurane (SEVO) and isoflurane (ISO) on electrophysiology,…”
Get full text

Postoperative acute kidney injury can be predicted by the novel biomarkers insulin-like growth factor-binding protein 7/tissue inhibitor of metalloproteinases-2 as early as 6 hours after surgery by Göcze, I, Herzog, R, Koch, M, Renner, P, Zeman, F, Graf, BM, Schlitt, HJ, Bein, T

Get full text

The Long Term Myotoxic Effects of Bupivacaine and Ropivacaine After Continuous Peripheral Nerve Blocks by Zink, Wolfgang, Bohl, Jürgen R. E., Hacke, Nicola, Sinner, Barbara, Martin, Eike, Graf, Bernhard M.

“…Compared with bupivacaine, acute myotoxicity of ropivacaine is less severe. Thus, in this study we compared the long term myotoxic effects of both drugs in a…”
Get full text

Evaluation of the CTrach™—an intubating LMA with integrated fibreoptic system by Timmermann, A, Russo, S, Graf, B.M.

“…The laryngeal mask airway CTrach™ (CTrach) is a variant of the intubating laryngeal mask airway. It provides visualization of the larynx during intubation and…”
Get full text

Contrast-enhanced ultrasonography in the ICU: promising tool or exciting toy? by Göcze, I, Herzog, R, Graf, BM, Agha, A, Schlitt, HJ, Pfister, K, Jung, E, Bein, T

Get full text

In vitro myotoxic effects of bupivacaine on rhabdomyosarcoma cells, immortalized and primary muscle cells by Metterlein, Thomas, Hoffmann, Petra, Späth, Ruth, Gruber, Michael, Graf, Bernhard M, Zink, Wolfgang

“…Rhabdomyosarcoma is a rare malignant skeletal muscle tumor. It mainly occurs in children and young adults and has an unsatisfactory prognosis. Prior studies…”
Get full text

Differences in cardiotoxicity of bupivacaine and Ropivacaine are the result of physicochemical and stereoselective properties by GRAF, Bernhard M, ABRAHAM, Ingo, EBERBACH, Nicole, KUNST, Gudrun, STOWE, David F, MARTIN, Eike

“…Ropivacaine is believed to have a lower incidence of clinical cardiac side effects than bupivacaine. The aim of this study was to compare the direct cardiac…”
Get full text

Treatment of palliative care emergencies by prehospital emergency physicians in Germany: an interview based investigation by Wiese, CHR, Bartels, UE, Ruppert, D, Marung, H, Luiz, T, Graf, BM, Hanekop, GG

“…Palliative care medical emergencies as a consequence of advanced cancer account for approximately 3% of all prehospital emergency cases. Therefore, prehospital…”
Get full text

Differential Effects of Bupivacaine on Intracellular Ca2+ Regulation: Potential Mechanisms of Its Myotoxicity by Zink, Wolfgang, Graf, Bernhard M, Sinner, Barbara, Martin, Eike, Fink, Rainer H. A, Kunst, Gudrun

“…BACKGROUNDBupivacaine produces skeletal muscle damage in clinical concentrations. It has been suggested that this may be caused by an increased intracellular…”
Get full text

The expenditure of computer-related worktime using clinical decision support systems in chronic pain therapy by Hecht, Timm, Bundscherer, Anika C, Lassen, Christoph L, Lindenberg, Nicole, Graf, Bernhard M, Ittner, Karl-Peter, Wiese, Christoph H R

“…Estimate the expenditure of computer-related worktime resulting from the use of clinical decision support systems (CDSS) to prevent adverse drug reactions…”
Get full text

Successful use of a new hand-held ECMO system in cardiopulmonary failure and bleeding shock after thrombolysis in massive post-partal pulmonary embolism by Arlt, M, Philipp, A, Iesalnieks, I, Kobuch, R, Graf, BM

“…Massive pulmonary embolism (PE) leads to cardiogenic shock and is associated with mortality rates of up to 75%.1 We report on a 27-year-old mother in…”
Get full text

Differential effects of bupivacaine and ropivacaine enantiomers on intracellular Ca2+ regulation in murine skeletal muscle fibers by ZINK, Wolfgang, MISSLER, Goetz, SINNER, Barbara, MARTIN, Eike, FINK, Rainer H. A, GRAF, Bernhard M

“…Increased intracellular Ca concentrations are considered to be a major pathomechanism in local anesthetic myotoxicity. Racemic bupivacaine and S-ropivacaine…”
Get full text

Comparison of caudal and intravenous clonidine in the prevention of agitation after sevoflurane in children by Bock, M., Kunz, P., Schreckenberger, R., Graf, B.M., Martin, E., Motsch, J.

“…In children, sevoflurane anaesthesia is associated with postanaesthetic agitation, which is treated mainly with opioids. We compared the effectiveness of…”
Get full text

The burden of acute kidney injury - a cross-sectional research in an university intensive care unit by Bergler, T, Bossauer, E, Thelen, K, Graf, BM, Banas, B, Schlitt, HJ, Gnann, W, Bein, T, Gocze, I

“…Issue Title: ESICM LIVES 2015…”
Get full text

High normal values of circulating immune cell subsets before surgery may be protective against development of postoperative acute kidney injury by Ehehalt, K, Renner, P, Zeman, F, Pfister, K, Riquelme, P, Graf, BM, Geissler, EK, Kasprzak, P, Schlitt, HJ, Bein, T, Hutchinson, JA, Gocze, I

“…Issue Title: ESICM LIVES 2015…”
Get full text