Search Results - "Gradecki, Sarah E."

Concordance of PD-L1 Expression Between Core Biopsy and Resection Specimens of Non–Small Cell Lung Cancer by Gradecki, Sarah E, Grange, Jacob S, Stelow, Edward B

“…The heterogeneity of programmed death ligand 1 (PD-L1) expression in non–small cell lung carcinomas (NSCLCs) is well studied; however, the method of tissue…”
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Tertiary lymphoid structures in desmoplastic melanoma have increased lymphocyte density, lymphocyte proliferation, and immune cross talk with tumor when compared to non-desmoplastic melanomas by Edmonds, Nicole L., Gradecki, Sarah E, Katyal, Priya, Lynch, Kevin T, Stowman, Anne M, Gru, Alejandro A, Engelhard, Victor H, Slingluff, Craig L, Mauldin, Ileana S.

“…Tertiary lymphoid structures (TLS) are ectopic lymphoid structures that can arise in human cancers and are associated with improved overall survival (OS) and…”
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Cutaneous mucormycosis with suspected dissemination in a patient with metastatic adrenocortical carcinoma by Dar, Nakul, Wills, Abigail, Berg, Scott, Gradecki, Sarah E., Cropley, Thomas G., Guffey, Darren

“…Mucormycosis is a frequently lethal fungal infection that most commonly affects patients with poorly controlled diabetes or other immunosuppressed states. We…”
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PRAME immunohistochemistry as an adjunct for diagnosis and histological margin assessment in lentigo maligna by Gradecki, Sarah E, Valdes‐Rodriguez, Rodrigo, Wick, Mark R, Gru, Alejandro A

“…Aims Lentigo maligna (LM), the most common type of melanoma in situ, is a diagnostically challenging lesion for pathologists due to abundant background…”
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PRAME expression in 155 cases of metastatic melanoma by Gradecki, Sarah E., Slingluff, Craig L., Gru, Alejandro A.

“…Background PRAME (preferentially expressed antigen in melanoma) is a promising immunohistochemical marker in distinguishing benign from malignant primary…”
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Giant cell tumor of soft tissue presenting as a lobulated, polypoid skin tumor by Stashower, Julian, Martin, Seth M., Gradecki, Sarah E., Guffey, Darren

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Case Report: Dynamic overlap of melanoma, sarcoidosis, and targeted therapy for BRAF-mutant melanoma by Dar, Nakul, Gradecki, Sarah E., Gaughan, Elizabeth M.

“…Targeted therapies, including BRAF and MEK inhibitors, are valuable treatment options for patients with unresectable or metastatic BRAF V600-mutant melanoma…”
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PRAME Expression in Endometrioid and Serous Endometrial Carcinoma: A Potential Immunotherapeutic Target and Possible Diagnostic Pitfall by Coppock, Joseph D., Gradecki, Sarah E., Mills, Anne M.

“…Preferentially expressed antigen in melanoma (PRAME) is a cancer testes antigen initially employed as a diagnostic marker for melanoma. Although negative in…”
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An unusual case of sarcomatoid renal cell carcinoma presenting in the skin by direct extension at a laparoscopic port site by Gradecki, Sarah E., Gru, Alejandro A.

“…Although renal cell carcinoma (RCC) is known for its propensity to metastasize widely throughout the body, cutaneous metastases are uncommon and seen in less…”
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High-grade Endometrial Carcinomas With Solid Basaloid Morphology and Geographic Necrosis Lacking Definitive Pilomatrix-like Features: Clinicopathologic Characteristics Including Aggressive Behavior and Novel Molecular Events by Carlson, David K, Painter, Cheyenne, Gradecki, Sarah E, Ring, Kari L, Williams, Eli S, Mills, Anne M

“…High-grade endometrioid carcinomas occasionally demonstrate solid basaloid morphology with geographic necrosis (SB-GN). This pattern is among the defining…”
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Use of Ultrasensitive RNA In Situ Hybridization for Determining Clonality in Cutaneous B-Cell Lymphomas and Lymphoid Hyperplasia Decreases Subsequent Use of Molecular Testing and Is Cost-effective by Craddock, Ashley P., Kane, William J., Raghavan, Shyam S., Williams, Eli S., Gru, Alejandro A., Gradecki, Sarah E.

“…Primary cutaneous B-cell lymphomas (PCBCLs) are diagnostically challenging entities due to significant overlap in clinical and morphologic features with…”
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Histopathology of primary cutaneous adenoid cystic carcinoma of the scrotum presenting with predominantly solid growth by Gradecki, Sarah E., Gru, Alejandro A., Rieger, Kerri E., Raghavan, Shyam S.

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Diagnostic Efficiency in Digital Pathology: A Comparison of Optical Versus Digital Assessment in 510 Surgical Pathology Cases by Mills, Anne M, Gradecki, Sarah E, Horton, Bethany J, Blackwell, Rebecca, Moskaluk, Christopher A, Mandell, James W, Mills, Stacey E, Cathro, Helen P

“…Prior work has shown that digital images and microscopic slides can be interpreted with comparable diagnostic accuracy. Although accuracy has been…”
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IDO1 Expression in Melanoma Metastases Is Low and Associated With Improved Overall Survival by Lynch, Kevin T., Gradecki, Sarah E., Kwak, Minyoung, Meneveau, Max O., Wages, Nolan A., Gru, Alejandro A., Slingluff, Craig L.

“…Indoleamine 2-3 dioxygenase 1 (IDO1) expression may contribute to immunologic escape by melanoma metastases. However, a recent clinical trial failed to…”
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Glioma-Associated Oncogene-1 Expression in Basal Cell Carcinoma and Its Histologic Mimics by Gradecki, Sarah E., Eid, Mary V., Pramoonjago, Patcharin, Wick, Mark R.

“…Basal cell carcinoma (BCC) is the most common skin cancer, and it has numerous histologic mimics with variable prognoses and treatments. Although some…”
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A rapidly growing nodule on the leg of an adolescent: A unique presentation of a non‐neural granular cell tumor by Hobbs, Landon K., Kozak, Merrick D., Gradecki, Sarah E., McGahren, Eugene D., Raghavan, Shyam S.

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Secondary Burn Progression Mitigated by an Adenosine 2A Receptor Agonist by Haywood, Nathan, Byler, Matthew R, Zhang, Aimee, Rotar, Evan P, Money, Dustin, Gradecki, Sarah E, Ta, Huy Q, Salmon, Morgan, Kron, Irving L, Laubach, Victor E, Mehaffey, J Hunter, Roeser, Mark E

“…Abstract Current burn therapy is largely supportive with limited therapies to curb secondary burn progression. Adenosine 2A receptor (A2AR) agonists have…”
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Palifermin-Associated Cutaneous Papular Rash of the Head and Neck by Lanyi, Shira, Pollack, Karlyn, Luu, Lydia, Gradecki, Sarah E, Gru, Alejandro, Flowers, Richard

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PRAME Expression in Endometrioid and Serous Endometrial Carcinoma: A Potential Immunotherapeutic Target and Possible Diagnostic Pitfall by Coppock, Joseph D., Gradecki, Sarah E., Mills, Anne M.

“…Preferentially expressed antigen in melanoma (PRAME) is a cancer testes antigen initially employed as a diagnostic marker for melanoma. Although negative in…”
Get full text

Use of Ultrasensitive RNA In Situ Hybridization for Determining Clonality in Cutaneous B-Cell Lymphomas and Lymphoid Hyperplasia Decreases Subsequent Use of Molecular Testing and Is Cost-effective by Craddock, Ashley P., Kane, William J., Raghavan, Shyam S., Williams, Eli S., Gru, Alejandro A., Gradecki, Sarah E.

“…Primary cutaneous B-cell lymphomas (PCBCLs) are diagnostically challenging entities due to significant overlap in clinical and morphologic features with…”
Get full text