Search Results - "Gracy, Jérome"

Structure Analysis Uncovers a Highly Diverse but Structurally Conserved Effector Family in Phytopathogenic Fungi by de Guillen, Karine, Ortiz-Vallejo, Diana, Gracy, Jérome, Fournier, Elisabeth, Kroj, Thomas, Padilla, André

“…Phytopathogenic ascomycete fungi possess huge effector repertoires that are dominated by hundreds of sequence-unrelated small secreted proteins. The molecular…”
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Recognition of the Magnaporthe oryzae Effector AVR-Pia by the Decoy Domain of the Rice NLR Immune Receptor RGA5 by Ortiz, Diana, de Guillen, Karine, Cesari, Stella, Chalvon, Véronique, Gracy, Jérome, Padilla, André, Kroj, Thomas

“…Nucleotide binding domain and leucine-rich repeat proteins (NLRs) are important receptors in plant immunity that allow recognition of pathogen effectors. The…”
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Resolving the activation mechanism of the D99N antiterminator LicT protein by Yang, Yinshan, Gracy, Jérome, Declerck, Nathalie, Déméné, Hélène

“…[Display omitted] •First NMR structure of an active LicT fragment containing effector and regulation modules.•The structure of modules is independent of the…”
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Structural Insights into of the Allosteric Activation of the LicT Antiterminator by PTS-Mediated Phosphorylation by Yang, Yinshan, Padilla, André, de Guillen, Karine, Mammri, Léa, Gracy, Jérome, Declerck, Nathalie, Déméné, Hélène

“…LicT belongs to an essential family of bacterial transcriptional antitermination proteins controlling the expression of sugar-metabolizing operons. When…”
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Structure Analysis Uncovers a Highly Diverse but Structurally Conserved Effector Family in Phytopathogenic Fungi: e1005228 by Guillen, Karine de, Ortiz-Vallejo, Diana, Gracy, Jérome, Fournier, Elisabeth, Kroj, Thomas, Padilla, André

“…Phytopathogenic ascomycete fungi possess huge effector repertoires that are dominated by hundreds of sequence-unrelated small secreted proteins. The molecular…”
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KNOTTIN: the database of inhibitor cystine knot scaffold after 10 years, toward a systematic structure modeling by Postic, Guillaume, Gracy, Jérôme, Périn, Charlotte, Chiche, Laurent, Gelly, Jean-Christophe

“…Abstract Knottins, or inhibitor cystine knots (ICKs), are ultra-stable miniproteins with multiple applications in drug design and medical imaging. These…”
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A new family of structurally conserved fungal effectors displays epistatic interactions with plant resistance proteins by Lazar, Noureddine, Mesarich, Carl H, Petit-Houdenot, Yohann, Talbi, Nacera, Li de la Sierra-Gallay, Ines, Zélie, Emilie, Blondeau, Karine, Gracy, Jérôme, Ollivier, Bénédicte, Blaise, Françoise, Rouxel, Thierry, Balesdent, Marie-Hélène, Idnurm, Alexander, van Tilbeurgh, Herman, Fudal, Isabelle

“…Recognition of a pathogen avirulence (AVR) effector protein by a cognate plant resistance (R) protein triggers a set of immune responses that render the plant…”
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SecretoMyc, a web-based database on mycobacteria secreted proteins and structure-based homology identification using bio-informatics tools by Gracy, Jérôme, Vallejos-Sanchez, Katherine, Cohen-Gonsaud, Martin

“…To better understand the interaction between the host and the Mycobacterium tuberculosis pathogen, it is critical to identify its potential secreted proteins…”
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Programmable receptors enable bacterial biosensors to detect pathological biomarkers in clinical samples by Chang, Hung-Ju, Zúñiga, Ana, Conejero, Ismael, Voyvodic, Peter L., Gracy, Jerome, Fajardo-Ruiz, Elena, Cohen-Gonsaud, Martin, Cambray, Guillaume, Pageaux, Georges-Philippe, Meszaros, Magdalena, Meunier, Lucy, Bonnet, Jerome

“…Bacterial biosensors, or bactosensors, are promising agents for medical and environmental diagnostics. However, the lack of scalable frameworks to…”
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@TOME 3.0: Interfacing Protein Structure Modeling and Ligand Docking by Pons, Jean-Luc, Reys, Victor, Grand, François, Moreau, Violaine, Gracy, Jerôme, Exner, Thomas E., Labesse, Gilles

“…[Display omitted] •@TOME 3.0 interfaces protein structure modeling and ligand docking.•@TOME 3.0 allows virtual screening against multiple conformations of…”
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Adaptive evolution in virulence effectors of the rice blast fungus Pyricularia oryzae by Le Naour-Vernet, Marie, Charriat, Florian, Gracy, Jérôme, Cros-Arteil, Sandrine, Ravel, Sébastien, Veillet, Florian, Meusnier, Isabelle, Padilla, André, Kroj, Thomas, Cesari, Stella, Gladieux, Pierre

“…Plant pathogens secrete proteins called effectors that target host cellular processes to promote disease. Recently, structural genomics has identified several…”
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Structure and modeling of knottins, a promising molecular scaffold for drug discovery by Gracy, Jérôme, Chiche, Laurent

“…The knottins are extremely stable miniproteins present in many species and are able to perform various tasks. Owing to its small size and its amazing…”
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The structural landscape and diversity of Pyricularia oryzae MAX effectors revisited by Lahfa, Mounia, Barthe, Philippe, de Guillen, Karine, Cesari, Stella, Raji, Mouna, Kroj, Thomas, Le Naour-Vernet, Marie, Hoh, François, Gladieux, Pierre, Roumestand, Christian, Gracy, Jérôme, Declerck, Nathalie, Padilla, André

“…Magnaporthe AVRs and ToxB-like (MAX) effectors constitute a family of secreted virulence proteins in the fungus Pyricularia oryzae (syn. Magnaporthe oryzae),…”
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Optimizing structural modeling for a specific protein scaffold: knottins or inhibitor cystine knots by Gracy, Jérôme, Chiche, Laurent

“…Knottins are small, diverse and stable proteins with important drug design potential. They can be classified in 30 families which cover a wide range of…”
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Comprehensive classification of the plant non-specific lipid transfer protein superfamily towards its sequence-structure-function analysis by Fleury, Cécile, Gracy, Jérôme, Gautier, Marie-Françoise, Pons, Jean-Luc, Dufayard, Jean-François, Labesse, Gilles, Ruiz, Manuel, de Lamotte, Frédéric

“…Non-specific Lipid Transfer Proteins (nsLTPs) are widely distributed in the plant kingdom and constitute a superfamily of related proteins. Several hundreds of…”
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KNOTTIN: the knottin or inhibitor cystine knot scaffold in 2007 by Gracy, Jérôme, Le-Nguyen, Dung, Gelly, Jean-Christophe, Kaas, Quentin, Heitz, Annie, Chiche, Laurent

“…The KNOTTIN database provides standardized information on the small disulfide-rich proteins with a knotted topology called knottins or inhibitor cystine knots…”
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A Mycobacterium tuberculosis Effector Targets Mitochondrion, Controls Energy Metabolism, and Limits Cytochrome c Exit by Martin, Marianne, deVisch, Angelique, Boudehen, Yves-Marie, Barthe, Philippe, Gutierrez, Claude, Turapov, Obolbek, Aydogan, Talip, Heriaud, Laurène, Gracy, Jerome, Neyrolles, Olivier, Mukamolova, Galina V, Letourneur, François, Cohen-Gonsaud, Martin

“…Host metabolism reprogramming is a key feature of Mycobacterium tuberculosis ( ) infection that enables the survival of this pathogen within phagocytic cells…”
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The KNOTTIN website and database: a new information system dedicated to the knottin scaffold by Gelly, Jean‐Christophe, Gracy, Jérôme, Kaas, Quentin, Le‐Nguyen, Dung, Heitz, Annie, Chiche, Laurent

“…The KNOTTIN website and database organize information about knottins or inhibitor cystine knots, small disulfide‐rich proteins with a knotted topology. Thanks…”
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Squash inhibitors: from structural motifs to macrocyclic knottins by Chiche, Laurent, Heitz, Annie, Gelly, Jean-Christophe, Gracy, Jérôme, Chau, Pham T T, Ha, Phan T, Hernandez, Jean-François, Le-Nguyen, Dung

“…In this article, we will first introduce the squash inhibitor, a well established family of highly potent canonical serine proteinase inhibitors isolated from…”
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Knottin cyclization: impact on structure and dynamics by Heitz, Annie, Avrutina, Olga, Le-Nguyen, Dung, Diederichsen, Ulf, Hernandez, Jean-François, Gracy, Jérôme, Kolmar, Harald, Chiche, Laurent

“…Present in various species, the knottins (also referred to as inhibitor cystine knots) constitute a group of extremely stable miniproteins with a plethora of…”
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