Search Results - "Grace, M E"

Angiotensin II-induced NADPH Oxidase Activation Impairs Insulin Signaling in Skeletal Muscle Cells by Wei, Yongzhong, Sowers, James R., Nistala, Ravi, Gong, Heping, Uptergrove, Grace M.-E., Clark, Suzanne E., Morris, E. Matthew, Szary, Nicholas, Manrique, Camila, Stump, Craig S.

“…The renin-angiotensin system (RAS) and reactive oxygen species (ROS) have been implicated in the development of insulin resistance and its related…”
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Does arthroscopic or open washout in native knee septic arthritis result in superior post-operative function? A systematic review and meta-analysis of randomised controlled trials and observational studies by Kennedy, Grace E M, Tharmaseelan, Abisha, Phillips, Jonathan R A, Evans, Jon T, Kunutsor, Setor K

“…Septic arthritis (SA) of the native knee joint is associated with significant morbidity. This review compared post-operative functional outcomes…”
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Prolonged exposure of mouse and human podocytes to insulin induces insulin resistance through lysosomal and proteasomal degradation of the insulin receptor by Lay, Abigail C., Hurcombe, Jenny A., Betin, Virginie M. S., Barrington, Fern, Rollason, Ruth, Ni, Lan, Gillam, Lawrence, Pearson, Grace M. E., Østergaard, Mette V., Hamidi, Hellyeh, Lennon, Rachel, Welsh, Gavin I., Coward, Richard J. M.

“…Aims/hypothesis Podocytes are insulin - responsive cells of the glomerular filtration barrier and are key in preventing albuminuria, a hallmark feature of…”
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NADPH Oxidase Contributes to Vascular Inflammation, Insulin Resistance, and Remodeling in the Transgenic (mRen2) Rat by Wei, Yongzhong, Whaley-Connell, Adam T, Chen, Kemin, Habibi, Javad, Uptergrove, Grace M.-E, Clark, Suzanne E, Stump, Craig S, Ferrario, Carlos M, Sowers, James R

“…Reduced insulin sensitivity is characteristic of various pathological conditions such as type 2 diabetes mellitus and hypertension. Angiotensin II, acting…”
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Deficiency in the Heat Stress Response Could Underlie Susceptibility to Metabolic Disease by Rogers, Robert S, Morris, E Matthew, Wheatley, Joshua L, Archer, Ashley E, McCoin, Colin S, White, Kathleen S, Wilson, David R, Meers, Grace M E, Koch, Lauren G, Britton, Steven L, Thyfault, John P, Geiger, Paige C

“…Heat treatment (HT) effectively prevents insulin resistance and glucose intolerance in rats fed a high-fat diet (HFD). The positive metabolic actions of heat…”
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Angiotensin II-induced non-alcoholic fatty liver disease is mediated by oxidative stress in transgenic TG(mRen2)27(Ren2) rats by Wei, Yongzhong, Clark, Suzanne E, Morris, E. Matthew, Thyfault, John P, Uptergrove, Grace M.E, Whaley-Connell, Adam T, Ferrario, Carlos M, Sowers, James R, Ibdah, Jamal A

“…Background/Aims Non-alcoholic fatty liver disease (NAFLD) is a common health problem and includes a spectrum of hepatic steatosis, steatohepatitis and…”
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Cavity transport effects in generator-collector electrochemical analysis of nitrobenzene by Lewis, Grace E M, Dale, Sara E C, Kasprzyk-Hordern, Barbara, Lubben, Anneke T, Barnes, Edward O, Compton, Richard G, Marken, Frank

“…Two types of generator-collector electrode systems, (i) a gold-gold interdigitated microband array and (ii) a gold-gold dual-plate microtrench, are compared…”
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Use of Singapore’s “Standard Details of Road Elements” for distance estimation in traffic crash reconstruction: A comparison with onsite measurements and Google Earth Pro by Lee, Rui Lin, Wong, Grace M.E., Wong, Sunny Y.S., Koh, Alaric C.W.

“…We report the use of the geometric design standard for road markings published in the “Standard Details of Road Elements” (‘SDRE’) by the Land Transport…”
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Female rats selectively bred for high intrinsic aerobic fitness are protected from ovariectomy-associated metabolic dysfunction by Vieira-Potter, Victoria J, Padilla, Jaume, Park, Young-Min, Welly, Rebecca J, Scroggins, Rebecca J, Britton, Steven L, Koch, Lauren G, Jenkins, Nathan T, Crissey, Jacqueline M, Zidon, Terese, Morris, E Matthew, Meers, Grace M E, Thyfault, John P

“…Ovariectomized rodents model human menopause in that they rapidly gain weight, reduce spontaneous physical activity (SPA), and develop metabolic dysfunction,…”
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Rats with high aerobic capacity display enhanced transcriptional adaptability and upregulation of bile acid metabolism in response to an acute high‐fat diet by Stierwalt, Harrison D., Morris, E. Matthew, Maurer, Adrianna, Apte, Udayan, Phillips, Kathryn, Li, Tiangang, Meers, Grace M. E., Koch, Lauren G., Britton, Steven L., Graf, Greg, Rector, R. Scott, Mercer, Kelly, Shankar, Kartik, Thyfault, John P.

“…Rats selectively bred for the high intrinsic aerobic capacity runner (HCR) or low aerobic capacity runner (LCR) show pronounced differences in susceptibility…”
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Increased aerobic capacity reduces susceptibility to acute high‐fat diet‐induced weight gain by Matthew Morris, E., Meers, Grace M.E., Koch, Lauren G., Britton, Steven L., MacLean, Paul S., Thyfault, John P.

“…Objective Aerobic capacity is the most powerful predictor of all‐cause mortality in humans; however, its role in the development of obesity and susceptibility…”
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Improving Identification of Cognitive Impairment in Fragility Fracture Patients: Impact of Educational Guidelines on Current Practice by Kennedy, Grace E. M., Mohandas, Parvathy, Anderson, Lesley A., Kennedy, Maurice, Shirley, Denise S. L.

“…Introduction: Cognitive impairment can hinder a fracture patient’s capacity to consent to surgery and negatively impact their postoperative recovery and…”
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Oxidative Stress-Mediated Mitochondrial Dysfunction Contributes to Angiotensin II-Induced Nonalcoholic Fatty Liver Disease in Transgenic Ren2 Rats by Wei, Yongzhong, Clark, Suzanne E, Thyfault, John P, Uptergrove, Grace M.E, Li, Wenhan, Whaley-Connell, Adam T, Ferrario, Carlos M, Sowers, James R, Ibdah, Jamal A

“…Emerging evidence indicates that impaired mitochondrial fatty acid β-oxidation plays a key role in liver steatosis. We have recently demonstrated that…”
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Parkinson's disease: connecting mitochondria to inflammasomes by Lawrence, Grace M.E.P., Holley, Caroline L., Schroder, Kate

“…Parkinson's disease (PD)-associated neurotoxins and mutations induce mitochondrial fission in vitro.Inducible mitochondrial fission promotes myeloid cell…”
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Bladder neck mobility is a heritable trait by Dietz, H.P., Hansell, N.K., Grace, M.E., Eldridge, A.M., Clarke, B., Martin, N.G.

“…Objective  Congenital connective tissue dysfunction may partly be responsible for female pelvic organ prolapse and urinary incontinence. We undertook a…”
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How can medical schools help in this crisis of care? by Pearson, Grace M E, Winter, Rebecca, Henderson, Emily J

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Come on mtDNA, light my fire by Lawrence, Grace M.E.P., Holley, Caroline L., Schroder, Kate

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Feedback-amplified electrochemical dual-plate boron-doped diamond microtrench detector for flow injection analysis by Lewis, Grace E. M., Gross, Andrew J., Kasprzyk-Hordern, Barbara, Lubben, Anneke T., Marken, Frank

“…An electrochemical flow cell with a boron‐doped diamond dual‐plate microtrench electrode has been developed and demonstrated for hydroquinone flow injection…”
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Mitochondrial dynamics in macrophages: divide to conquer or unite to survive? by Afroz, Syeda Farhana, Raven, Karoline D, Lawrence, Grace M E P, Kapetanovic, Ronan, Schroder, Kate, Sweet, Matthew J

“…Mitochondria have long been appreciated as the metabolic hub of cells. Emerging evidence also posits these organelles as hubs for innate immune signalling and…”
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A narrative overview of undergraduate geriatric medicine education worldwide by Pearson, Grace M E, Ben-Shlomo, Yoav, Henderson, Emily J

“…There is a mismatch between the healthcare needs of the ageing population worldwide and the amount of education medical students receive in geriatric medicine…”
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