Search Results - "Grace, AA"

The Hippocampal-VTA Loop: Controlling the Entry of Information into Long-Term Memory by Lisman, John E., Grace, Anthony A.

“…In this article we develop the concept that the hippocampus and the midbrain dopaminergic neurons of the ventral tegmental area (VTA) form a functional loop…”
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Dopaminergic modulation of limbic and cortical drive of nucleus accumbens in goal-directed behavior by Goto, Yukiori, Grace, Anthony A

“…Goal-directed behavior is believed to involve interactions of prefrontal cortical and limbic inputs in the nucleus accumbens (NAcc), and their modulation by…”
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Oxidative stress-driven parvalbumin interneuron impairment as a common mechanism in models of schizophrenia by Steullet, P, Cabungcal, J-H, Coyle, J, Didriksen, M, Gill, K, Grace, A A, Hensch, T K, LaMantia, A-S, Lindemann, L, Maynard, T M, Meyer, U, Morishita, H, O'Donnell, P, Puhl, M, Cuenod, M, Do, K Q

“…Parvalbumin inhibitory interneurons (PVIs) are crucial for maintaining proper excitatory/inhibitory balance and high-frequency neuronal synchronization. Their…”
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Synaptic interactions among excitatory afferents to nucleus accumbens neurons: hippocampal gating of prefrontal cortical input by O'Donnell, P, Grace, AA

“…The interactions among excitatory inputs arising from the prefrontal cortex, amygdala, and hippocampus, and innervating nucleus accumbens neurons were studied…”
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Cortical regulation of subcortical dopamine systems and its possible relevance to schizophrenia by GRACE, A. A

“…A unique model of DA system regulation is presented, in which tonic steady-state DA levels in the ECF act to down-regulate the response of the system to…”
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Pathophysiology of psychosis and novel approaches to treatment by Grace, AA

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Diazepam reverses increased anxiety-like behavior, social behavior deficit, and dopamine dysregulation following withdrawal from acute amphetamine by Rincón-Cortés, Millie, Gagnon, Kimberly G, Dollish, Hannah K, Grace, Anthony A

“…Psychostimulants such as amphetamine (AMPH) increase dopamine (DA) release from ventral tegmental area (VTA) neurons, which is associated with their acute…”
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The Laterodorsal Tegmentum Is Essential for Burst Firing of Ventral Tegmental Area Dopamine Neurons by Lodge, D. J., Grace, A. A.

“…In response to behaviorally salient stimuli, dopamine (DA) neurons fire in bursts. Burst firing induces a large transient increase in synaptic DA and is…”
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The Yin and Yang of dopamine release: a new perspective by Goto, Yukiori, Otani, Satoru, Grace, Anthony A.

“…Dopamine has undergone extensive investigation due to its known involvement in a number of neurological and psychiatric disorders. In particular, studies into…”
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A Subpopulation of Neurons in the Medial Prefrontal Cortex Encodes Emotional Learning with Burst and Frequency Codes through a Dopamine D 4 Receptor-Dependent Basolateral Amygdala Input by Laviolette, Steven R., Lipski, Witold J., Grace, Anthony A.

“…The basolateral nucleus of the amygdala (BLA) and medial prefrontal cortex (mPFC) are involved importantly in the processing and encoding of emotionally…”
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The Hippocampus Modulates Dopamine Neuron Responsivity by Regulating the Intensity of Phasic Neuron Activation by LODGE, Daniel J, GRACE, Anthony A

“…Aberrant dopamine (DA) signaling has been advanced as a contributing factor to the pathophysiology of a number of psychiatric conditions including…”
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In vitro manganese-dependent cross-talk between Streptococcus mutans VicK and GcrR: implications for overlapping stress response pathways by Downey, Jennifer S, Mashburn-Warren, Lauren, Ayala, Eduardo A, Senadheera, Dilani B, Hendrickson, Whitney K, McCall, Lathan W, Sweet, Julie G, Cvitkovitch, Dennis G, Spatafora, Grace A, Goodman, Steven D

“…Streptococcus mutans, a major acidogenic component of the dental plaque biofilm, has a key role in caries etiology. Previously, we demonstrated that the VicRK…”
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Gating within limbic-cortical circuits and its alteration in a developmental disruption model of schizophrenia by Grace, Anthony A.

“…Schizophrenia is comprised of several symptom subtypes, including positive symptoms, negative symptoms, disorganization syndrome, and cognitive disturbances…”
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Dopamine-Dependent Interactions between Limbic and Prefrontal Cortical Plasticity in the Nucleus Accumbens: Disruption by Cocaine Sensitization by Goto, Yukiori, Grace, Anthony A.

“…The prefrontal cortex and the hippocampus exhibit converging projections to the nucleus accumbens and have functional reciprocal connections via indirect…”
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The catechol-O-methyltransferase polymorphism: Relations to the tonic-phasic dopamine hypothesis and neuropsychiatric phenotypes by BILDER, Robert M, VOLAVKA, Jan, LACHMAN, Herbert M, GRACES, Anthony A

“…Diverse phenotypic associations with the catechol-O-methyltransferase (COMT) Val158Met polymorphism have been reported. We suggest that some of the complex…”
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Afferent modulation of dopamine neuron firing differentially regulates tonic and phasic dopamine transmission by Floresco, Stan B, Grace, Anthony A, West, Anthony R, Ash, Brian, Moore, Holly

“…The mesolimbic dopamine system is centrally involved in reward and goal-directed behavior, and it has been implicated in multiple psychiatric disorders…”
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Cannabinoids Potentiate Emotional Learning Plasticity in Neurons of the Medial Prefrontal Cortex through Basolateral Amygdala Inputs by Laviolette, Steven R, Grace, Anthony A

“…Cannabinoids represent one of the most commonly used hallucinogenic drug classes. In addition, cannabis use is a primary risk factor for schizophrenia in…”
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Physiology of the normal and dopamine-depleted basal ganglia: Insights into levodopa pharmacotherapy by Grace, Anthony A.

“…Dopamine (DA) neurons exist in two activity states; either spontaneously firing or quiescent and nonfiring. When faced with a behavioral demand, the quiescent…”
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Anxiety-like behavior in Rett syndrome: characteristics and assessment by anxiety scales by Barnes, Katherine V, Coughlin, Francesca R, O'Leary, Heather M, Bruck, Natalie, Bazin, Grace A, Beinecke, Emily B, Walco, Alexandra C, Cantwell, Nicole G, Kaufmann, Walter E

“…Rett syndrome (RTT) is a severe neurodevelopmental disorder characterized by regression of language and motor skills, cognitive impairment, and frequent…”
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Corticotropin-Releasing Hormone Directly Activates Noradrenergic Neurons of the Locus Ceruleus Recorded In Vitro by Jedema, Hank P, Grace, Anthony A

“…The neuropeptide corticotropin-releasing hormone (CRH) activates locus ceruleus (LC) neurons, thereby increasing norepinephrine levels throughout the CNS…”
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