Search Results - "Grabner, Hannes"
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Genome-scale RNAi profiling of cell division in human tissue culture cells
Published in Nature cell biology (01-12-2007)“…Cell division is fundamental for all organisms. Here we report a genome-scale RNA-mediated interference screen in HeLa cells designed to identify human genes…”
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A Genome-Wide Visual Screen Reveals a Role for Sphingolipids and Ergosterol in Cell Surface Delivery in Yeast
Published in Proceedings of the National Academy of Sciences - PNAS (13-12-2005)“…Recently synthesized proteins are sorted at the trans-Golgi network into specialized routes for exocytosis. Surprisingly little is known about the underlying…”
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Genome-wide analysis of human kinases in clathrin- and caveolae/raft-mediated endocytosis
Published in Nature (07-07-2005)“…Endocytosis is a key cellular process, encompassing different entry routes and endocytic compartments. To what extent endocytosis is subjected to high-order…”
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Genome-wide resources of endoribonuclease-prepared short interfering RNAs for specific loss-of-function studies
Published in Nature methods (01-04-2007)“…RNA interference (RNAi) has become an important technique for loss-of-gene-function studies in mammalian cells. To achieve reliable results in an RNAi…”
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An endoribonuclease-prepared siRNA screen in human cells identifies genes essential for cell division
Published in Nature (23-12-2004)“…RNA interference (RNAi) is an evolutionarily conserved defence mechanism whereby genes are specifically silenced through degradation of messenger RNAs; this…”
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