Search Results - "Grabbe, Alice"

Scaffold-Hopping Approach To Discover Potent, Selective, and Efficacious Inhibitors of NF-κB Inducing Kinase by Blaquiere, Nicole, Castanedo, Georgette M, Burch, Jason D, Berezhkovskiy, Leonid M, Brightbill, Hans, Brown, Suzanne, Chan, Connie, Chiang, Po-Chang, Crawford, James J, Dong, Teresa, Fan, Peter, Feng, Jianwen, Ghilardi, Nico, Godemann, Robert, Gogol, Emily, Grabbe, Alice, Hole, Alison J, Hu, Baihua, Hymowitz, Sarah G, Alaoui Ismaili, Moulay Hicham, Le, Hoa, Lee, Patrick, Lee, Wyne, Lin, Xingyu, Liu, Ning, McEwan, Paul A, McKenzie, Brent, Silvestre, Hernani L, Suto, Eric, Sujatha-Bhaskar, Swathi, Wu, Guosheng, Wu, Lawren C, Zhang, Yamin, Zhong, Zoe, Staben, Steven T

“…NF-κB-inducing kinase (NIK) is a protein kinase central to the noncanonical NF-κB pathway downstream from multiple TNF receptor family members, including BAFF,…”
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Filling a nick in NIK: Extending the half-life of a NIK inhibitor through structure-based drug design by Crawford, James J., Feng, Jianwen, Brightbill, Hans D., Johnson, Adam R., Wright, Matthew, Kolesnikov, Aleksandr, Lee, Wendy, Castanedo, Georgette M., Do, Steven, Blaquiere, Nicole, Staben, Steven T., Chiang, Po-Chang, Fan, Peter W., Baumgardner, Matt, Wong, Susan, Godemann, Robert, Grabbe, Alice, Wiegel, Catharina, Sujatha-Bhaskar, Swathi, Hymowitz, Sarah G., Liau, Nicholas, Hsu, Peter L., McEwan, Paul A., Ismaili, Moulay Hicham Alaoui, Landry, Matthew L.

“…[Display omitted] Inhibition of NF-κB inducing kinase (NIK) has been pursued as a promising therapeutic target for autoimmune disorders due to its highly…”
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