Search Results - "Grüner, N."

Minimal T-Cell-Stimulatory Sequences and Spectrum of HLA Restriction of Immunodominant CD4+ T-Cell Epitopes within Hepatitis C Virus NS3 and NS4 Proteins by GERLACH, J. T, ULSENHEIMER, A, VOGLER, A, ZACHOVAL, R, PAPE, G. R, DIEPOLDER, H. M, GRÜNER, N. H, JUNE, M.-C, SCHRAUT, W, SCHIRREN, C.-A, HEEG, M, SCHOLZ, S, WITTER, K, ZAHN, R

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Association of Hepatitis C Virus—Specific CD8+ T Cells with Viral Clearance in Acute Hepatitis C by Grüner, Norbert H., Gerlach, Tilman J., Jung, Maria-Christina, Diepolder, Helmut M., Schirren, Carl Albrecht, Schraut, Winfried W., Hoffmann, Robert, Zachoval, Reinhart, Santantonio, Teresa, Cucchiarini, M., Cerny, Andreas, Pape, Gerd R.

“…CD8+ T lymphocytes play a major role in antiviral immune defense. Their significance for acute hepatitis C is unclear. Our aim was to correlate the CD8+ T cell…”
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The German Hep-Net acute hepatitis C cohort: impact of viral and host factors on the initial presentation of acute hepatitis C virus infection by Deterding, K, Wiegand, J, Grüner, N, Hahn, A, Jäckel, E, Jung, M C, Buggisch, P, Galle, P, Berg, T, Hinrichsen, H, Potthoff, A, Zeuzem, S, Cornberg, M, Manns, M, Wedemeyer, H

“…The impacts of viral load, genotype, age, sex and BMI on the clinical course of acute hepatitis C are poorly defined. Here we studied 259 patients with acute…”
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Global accumulation of circRNAs during aging in Caenorhabditis elegans by Cortés-López, Mariela, Gruner, Matthew R, Cooper, Daphne A, Gruner, Hannah N, Voda, Alexandru-Ioan, van der Linden, Alexander M, Miura, Pedro

“…Circular RNAs (CircRNAs) are a newly appreciated class of RNAs that lack free 5' and 3' ends, are expressed by the thousands in diverse forms of life, and are…”
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48 EARLY VERSUS DELAYED TREATMENT OF ACUTE HEPATITIS C: FINAL RESULTS OF THE RANDOMIZED CONTROLLED GERMAN HEP-NET ACUTE HCV-III STUDY by Deterding, K, Grüner, N, Buggisch, P, Wiegand, J, Galle, P, Spengler, U, Hinrichsen, H, Berg, T, Potthoff, A, Malek, N, Diepolder, H, Feyerabend, S, Cornberg, M, Jung, M.C, Manns, M.P, Wedemeyer, H

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Lhx3/4 initiates a cardiopharyngeal-specific transcriptional program in response to widespread FGF signaling by Pickett, C J, Gruner, Hannah N, Davidson, Bradley

“…Individual signaling pathways, such as fibroblast growth factors (FGFs), can regulate a plethora of inductive events. According to current paradigms,…”
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Role of the specific T-cell response for clearance and control of hepatitis C virus by Pape, G. R., Gerlach, T. J., Diepolder, H. M., Grüner, N., Jung, M.-C., Santantonio, T.

“…T cells are believed to be the main players in antiviral defence. To investigate the role of the specific CD4+ T cell response for clearance and control of the…”
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1047 EARLY VERSUS DELAYED TREATMENT OF ACUTE HEPATITIS C: THE GERMAN HEP-NET ACUTE HCV-III STUDY – A RANDOMIZED CONTROLLED TRIAL by Deterding, K, Grüner, N, Wiegand, J, Buggisch, P, Galle, P, Spengler, U, Hinrichsen, H, Berg, T, Cornberg, M, Potthoff, A, Diepolder, H, Feyerabend, S, Jung, M.C, Manns, M.P, Wedemeyer, H

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A vigorous virus‐specific CD4+ T cell response may contribute to the association of HLA‐DR13 with viral clearance in hepatitis B by DIEPOLDER, H. M, JUNG, M.-C, PAPE, G. R, KELLER, E, SCHRAUT, W, GERLACH, J.-T, GRÜNER, N, ZACHOVAL, R, HOFFMANN, R. M, SCHIRREN, C.-A, SCHOLZ, S

“…A strong virus‐specific CD4+ and CD8+ T lymphocyte response to hepatitis B virus (HBV) has been associated with viral clearance, but little is known about…”
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SARS-CoV-2 ORF3A interacts with the Clic-like chloride channel-1 ( CLCC1 ) and triggers an unfolded protein response by Gruner, Hannah N, Zhang, Yaohuan, Shariati, Kaavian, Yiv, Nicholas, Hu, Zicheng, Wang, Yuhao, Hejtmancik, J Fielding, McManus, Michael T, Tharp, Kevin, Ku, Gregory

“…Understanding the interactions between SARS-CoV-2 and host cell machinery may reveal new targets to treat COVID-19. We focused on an interaction between the…”
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Examining the evidence for extracellular RNA function in mammals by Gruner, Hannah N., McManus, Michael T.

“…The presence of RNAs in the extracellular milieu has sparked the hypothesis that RNA may play a role in mammalian cell–cell communication. As functional…”
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Haploidentical bone marrow transplantation with post-grafting cyclophosphamide: multicenter experience with an alternative salvage strategy by Tuve, S, Gayoso, J, Scheid, C, Radke, J, Kiani, A, Serrano, D, Platzbecker, U, Rodríguez-Macías, G, Wermke, M, Holtick, U, Balsalobre, P, Middeke, J M, Shayegi, N, Chemnitz, J M, Krause, A, Gruner, N, Füssel, M, Schetelig, J, Thiede, C, Ehninger, G, Hallek, M, Díez-Martín, J L, Bornhäuser, M

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Elimination of Calm1 long 3'-UTR mRNA isoform by CRISPR-Cas9 gene editing impairs dorsal root ganglion development and hippocampal neuron activation in mice by Bae, Bongmin, Gruner, Hannah N, Lynch, Maebh, Feng, Ting, So, Kevin, Oliver, Daniel, Mastick, Grant S, Yan, Wei, Pieraut, Simon, Miura, Pedro

“…The majority of mouse and human genes are subject to alternative cleavage and polyadenylation (APA), which most often leads to the expression of two or more…”
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Robo1 and 2 Repellent Receptors Cooperate to Guide Facial Neuron Cell Migration and Axon Projections in the Embryonic Mouse Hindbrain by Gruner, Hannah N., Kim, Minkyung, Mastick, Grant S.

“…The wild-type developmental time course of facial branchiomotor nucleus is shown on the left side of the hindbrain, and the altered development in Robo1/2…”
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KNa1.1 channels as a target for treating early-onset epilepsy by Hu, Zicheng, Gruner, Hannah N., Gagacheva, Jana, Gulyaeva, Olga

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Hepatitis C — Therapie-Update: Was gibt’s Neues an der Wirkstofffront? by Raziorrouh, B., Grüner, N.

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Lhx3/4 initiates a cardiopharyngeal-specific transcriptional program in response to widespread FGF signaling by C J Pickett, Hannah N Gruner, Bradley Davidson

“…Individual signaling pathways, such as fibroblast growth factors (FGFs), can regulate a plethora of inductive events. According to current paradigms,…”
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Virus-Specific Lymphokine Production Differs Quantitatively but Not Qualitatively in Acute and Chronic Hepatitis B Infection by Jung, Maria-Christina, Hartmann, Bertram, Gerlach, Jörn-Tilman, Diepolder, Helmut, Gruber, Rudolf, Schraut, Winfried, Grüner, Norbert, Zachoval, Reinhart, Hoffmann, Robert, Santantonio, Teresa, Wächtler, Martin, Pape, Gerd Rudolf

“…Cytokines that are secreted as a response to viral antigen not only have direct antiviral properties but also crucially influence immune reactions determining…”
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ISL1-based LIM complexes control Slit2 transcription in developing cranial motor neurons by Kim, Kyung-Tai, Kim, Namhee, Kim, Hwan-Ki, Lee, Hojae, Gruner, Hannah N., Gergics, Peter, Park, Chungoo, Mastick, Grant S., Park, Hae-Chul, Song, Mi-Ryoung

“…LIM-homeodomain (HD) transcription factors form a multimeric complex and assign neuronal subtype identities, as demonstrated by the hexameric ISL1-LHX3 complex…”
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Vigorous Peripheral Blood Cytotoxic T Cell Response during the Acute Phase of Hepatitis C Virus Infection by Cucchiarini, Magali, Kammer, Andreas R., Grabscheid, Benno, Diepolder, Helmut M., Gerlach, Tilman J., Grüner, Norbert, Santantonio, Teresa, Reichen, Jürg, Pape, Gerd R., Cerny, Andreas

“…After infection by hepatitis C virus (HCV), a minority of patients develop acute symptomatic disease and some of them are able to clear the virus. In this…”
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