Search Results - "Grüner, Anne Charlotte"

Breadth of humoral response and antigenic targets of sporozoite‐inhibitory antibodies associated with sterile protection induced by controlled human malaria infection by Peng, Kaitian, Goh, Yun Shan, Siau, Anthony, Franetich, Jean‐François, Chia, Wan Ni, Ong, Alice Soh Meoy, Malleret, Benoit, Wu, Ying Ying, Snounou, Georges, Hermsen, Cornelus C., Adams, John H., Mazier, Dominique, Preiser, Peter R., Sauerwein, Robert W., Grüner, Anne‐Charlotte, Rénia, Laurent

“…Summary The development of an effective malaria vaccine has remained elusive even until today. This is because of our incomplete understanding of the immune…”
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On the diversity of malaria parasites in African apes and the origin of Plasmodium falciparum from Bonobos by Krief, Sabrina, Escalante, Ananias A, Pacheco, M Andreina, Mugisha, Lawrence, André, Claudine, Halbwax, Michel, Fischer, Anne, Krief, Jean-Michel, Kasenene, John M, Crandfield, Mike, Cornejo, Omar E, Chavatte, Jean-Marc, Lin, Clara, Letourneur, Franck, Grüner, Anne Charlotte, McCutchan, Thomas F, Rénia, Laurent, Snounou, Georges

“…The origin of Plasmodium falciparum, the etiological agent of the most dangerous forms of human malaria, remains controversial. Although investigations of…”
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Invasion of host cells by malaria parasites: a tale of two protein families by Iyer, Jayasree, Grüner, Anne Charlotte, Rénia, Laurent, Snounou, Georges, Preiser, Peter R

“…Malaria parasites are obligate intracellular parasites whose invasive stages select and invade the unique host cell in which they can develop with exquisite…”
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An integrated lab-on-chip for rapid identification and simultaneous differentiation of tropical pathogens by Tan, Jeslin J L, Capozzoli, Monica, Sato, Mitsuharu, Watthanaworawit, Wanitda, Ling, Clare L, Mauduit, Marjorie, Malleret, Benoît, Grüner, Anne-Charlotte, Tan, Rosemary, Nosten, François H, Snounou, Georges, Rénia, Laurent, Ng, Lisa F P

“…Tropical pathogens often cause febrile illnesses in humans and are responsible for considerable morbidity and mortality. The similarities in clinical symptoms…”
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Minimal Role for the Circumsporozoite Protein in the Induction of Sterile Immunity by Vaccination with Live Rodent Malaria Sporozoites by Mauduit, Marjorie, Tewari, Rita, Depinay, Nadya, Kayibanda, Michèle, Lallemand, Eliette, Chavatte, Jean-Marc, Snounou, Georges, Rénia, Laurent, Grüner, Anne Charlotte

“…Immunization with live Plasmodium sporozoites under chloroquine prophylaxis (Spz plus CQ) induces sterile immunity against sporozoite challenge in rodents and,…”
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Species-Specific Inhibition of Cerebral Malaria in Mice Coinfected with Plasmodium spp by Voza, Tatiana, Vigário, Ana M, Belnoue, Elodie, Grůner, Anne Charlotte, Deschemin, Jean-Christophe, Kayibanda, Michèle, Delmas, Florian, Janse, Chris J, Franke-Fayard, Blandine, Waters, Andrew P, Landau, Irène, Snounou, Georges, Rénia, Laurent

“…Recent epidemiological observations suggest that clinical evolution of Plasmodium falciparum infections might be influenced by the concurrent presence of…”
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Do Apoptotic Plasmodium-Infected Hepatocytes Initiate Protective Immune Responses? by Rénia, Laurent, Marañón, Conception, Hosmalin, Anne, Grüner, Anne Charlotte, Silvie, Olivier, Snounou, Georges

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Expression of the Erythrocyte-Binding Antigen 175 in Sporozoites and in Liver Stages of Plasmodium falciparum by Grüner, Anne Charlotte, Brahimi, Karima, Letourneur, Franck, Rénia, Laurent, Eling, Wijnand, Snounou, Georges, Druilhe, Pierre

“…Screening of a Plasmodium falciparum genomic expression library for antigens expressed at the pre-erythrocytic stages resulted in the isolation of a…”
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Cerebral malaria: Mysteries at the blood-brain barrier by Rénia, Laurent, Howland, Shanshan Wu, Claser, Carla, Gruner, Anne Charlotte, Suwanarusk, Rossarin, Teo, Teck-Hui, Russell, Bruce, Ng, Lisa F.P.

“…Cerebral malaria is the most severe pathology caused by the malaria parasite, Plasmodium falciparum. The pathogenic mechanisms leading to cerebral malaria are…”
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Inhibitory effect of TNF-α on malaria pre-erythrocytic stage development: influence of host hepatocyte/parasite combinations by Depinay, Nadya, Franetich, Jean Francois, Grüner, Anne Charlotte, Mauduit, Marjorie, Chavatte, Jean-Marc, Luty, Adrian J F, van Gemert, Geert-Jan, Sauerwein, Robert W, Siksik, Jean-Michel, Hannoun, Laurent, Mazier, Dominique, Snounou, Georges, Rénia, Laurent

“…The liver stages of malaria parasites are inhibited by cytokines such as interferon-γ or Interleukin (IL)-6. Binding of these cytokines to their receptors at…”
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Vaccination with Live Plasmodium yoelii Blood Stage Parasites under Chloroquine Cover Induces Cross-Stage Immunity against Malaria Liver Stage by Belnoue, Elodie, Voza, Tatiana, Costa, Fabio T. M, Gruner, Anne Charlotte, Mauduit, Marjorie, Rosa, Daniela Santoro, Depinay, Nadya, Kayibanda, Michele, Vigario, Ana Margarida, Mazier, Dominique, Snounou, Georges, Sinnis, Photini, Renia, Laurent

“…Immunity to malaria has long been thought to be stage-specific. In this study we show that immunization of BALB/c mice with live erythrocytes infected with…”
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Neutralizing Antibodies against Plasmodium falciparum Associated with Successful Cure after Drug Therapy by Goh, Yun Shan, Peng, Kaitian, Chia, Wan Ni, Siau, Anthony, Chotivanich, Kesinee, Gruner, Anne-Charlotte, Preiser, Peter, Mayxay, Mayfong, Pukrittayakamee, Sasithon, Sriprawat, Kanlaya, Nosten, Francois, White, Nicholas J, Renia, Laurent

“…An effective antibody response can assist drug treatment to contribute to better parasite clearance in malaria patients. To examine this, sera were obtained…”
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Recombinant human IFN-alpha inhibits cerebral malaria and reduces parasite burden in mice by Vigário, Ana Margarida, Belnoue, Elodie, Grüner, Anne Charlotte, Mauduit, Marjorie, Kayibanda, Michèle, Deschemin, Jean-Christophe, Marussig, Myriam, Snounou, Georges, Mazier, Dominique, Gresser, Ion, Rénia, Laurent

“…Most C57BL/6 mice infected i.p. with Plasmodium berghei ANKA (PbA) die between 7 and 14 days with neurologic signs, and the remainder die later (>15 days) with…”
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Sterile protection against malaria is independent of immune responses to the circumsporozoite protein by Grüner, Anne Charlotte, Mauduit, Marjorie, Tewari, Rita, Romero, Jackeline F, Depinay, Nadya, Kayibanda, Michèle, Lallemand, Eliette, Chavatte, Jean-Marc, Crisanti, Andrea, Sinnis, Photini, Mazier, Dominique, Corradin, Giampietro, Snounou, Georges, Rénia, Laurent

“…Research aimed at developing vaccines against infectious diseases generally seeks to induce robust immune responses to immunodominant antigens. This approach…”
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Skin‐draining lymph node priming is sufficient to induce sterile immunity against pre‐erythrocytic malaria by Obeid, Michel, Franetich, Jean‐François, Lorthiois, Audrey, Gego, Audrey, Grüner, Anne Charlotte, Tefit, Maurel, Boucheix, Claude, Snounou, Georges, Mazier, Dominique

“…The Plasmodium ‐infected hepatocyte has been considered necessary to prime the immune responses leading to sterile protection after vaccination with attenuated…”
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Genetic diversity in new members of the reticulocyte binding protein family in Thai Plasmodium vivax isolates by Kosaisavee, Varakorn, Lek-Uthai, Usa, Suwanarusk, Rossarin, Grüner, Anne Charlotte, Russell, Bruce, Nosten, Francois, Rénia, Laurent, Snounou, Georges

“…Plasmodium vivax merozoites specifically invade reticulocytes. Until recently, two reticulocyte-binding proteins (Pvrbp1 and Pvrbp2) expressed at the apical…”
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Practical PCR genotyping protocols for Plasmodium vivax using Pvcs and Pvmsp1 by Imwong, Mallika, Pukrittayakamee, Sasithon, Grüner, Anne Charlotte, Rénia, Laurent, Letourneur, Frank, Looareesuwan, Sornchai, White, Nicholas J, Snounou, Georges

“…Plasmodium vivax is the second most prevalent malaria parasite affecting more than 75 million people each year, mostly in South America and Asia. In addition…”
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A role for immune responses against non-CS components in the cross-species protection induced by immunization with irradiated malaria sporozoites by Mauduit, Marjorie, Grüner, Anne Charlotte, Tewari, Rita, Depinay, Nadya, Kayibanda, Michèle, Chavatte, Jean-Marc, Franetich, Jean-François, Crisanti, Andrea, Mazier, Dominique, Snounou, Georges, Rénia, Laurent

“…Immunization with irradiated Plasmodium sporozoites induces sterile immunity in rodents, monkeys and humans. The major surface component of the sporozoite the…”
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Are Extensive T Cell Epitope Polymorphisms in the Plasmodium falciparum Circumsporozoite Antigen, a Leading Sporozoite Vaccine Candidate, Selected by Immune Pressure? by Kumkhaek, Chutima, Phra-ek, Kooruethai, Renia, Laurent, Singhasivanon, Pratap, Looareesuwan, Sornchai, Hirunpetcharat, Chakrit, White, Nicholas J, Brockman, Alan, Gruner, Anne Charlotte, Lebrun, Nicolas, Alloueche, Ali, Nosten, Francois, Khusmith, Srisin, Snounou, Georges

“…Protective cellular immune responses depend on MHC presentation of pathogen-derived Ag fragments. MHC diversity renders this process sensitive to point…”
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The Activity of Escherichia coli Dihydroorotate Dehydrogenase Is Dependent on a Conserved Loop Identified by Sequence Homology, Mutagenesis, and Limited Proteolysis by Björnberg, Olof, Grüner, Anne-Charlotte, Roepstorff, Peter, Jensen, Kaj Frank

“…Dihydroorotate dehydrogenase catalyzes the oxidation of dihydroorotate to orotate. The enzyme from Escherichia coli was overproduced and characterized in…”
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