Search Results - "Grøftehauge, Morten K."

Protein-ligand interactions investigated by thermal shift assays (TSA) and dual polarization interferometry (DPI) by Grøftehauge, Morten K., Hajizadeh, Nelly R., Swann, Marcus J., Pohl, Ehmke

“…Over the last decades, a wide range of biophysical techniques investigating protein–ligand interactions have become indispensable tools to complement…”
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Structural and Biochemical Characterization of Chlamydia trachomatis DsbA Reveals a Cysteine-Rich and Weakly Oxidising Oxidoreductase by Christensen, Signe, Grøftehauge, Morten K, Byriel, Karl, Huston, Wilhelmina M, Furlong, Emily, Heras, Begoña, Martin, Jennifer L, McMahon, Róisín M

“…The Gram negative bacteria Chlamydia trachomatis is an obligate intracellular human pathogen that can cause pelvic inflammatory disease, infertility and…”
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Functional and phylogenetic evidence of a bacterial origin for the first enzyme in sphingolipid biosynthesis in a phylum of eukaryotic protozoan parasites by Mina, John G., Thye, Julie K., Alqaisi, Amjed Q.I., Bird, Louise E., Dods, Robert H., Grøftehauge, Morten K., Mosely, Jackie A., Pratt, Steven, Shams-Eldin, Hosam, Schwarz, Ralph T., Pohl, Ehmke, Denny, Paul W.

“…Toxoplasma gondii is an obligate, intracellular eukaryotic apicomplexan protozoan parasite that can cause fetal damage and abortion in both animals and humans…”
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Structure of the Acinetobacter baumannii Dithiol Oxidase DsbA Bound to Elongation Factor EF-Tu Reveals a Novel Protein Interaction Site by Premkumar, Lakshmanane, Kurth, Fabian, Duprez, Wilko, Grøftehauge, Morten K., King, Gordon J., Halili, Maria A., Heras, Begoña, Martin, Jennifer L.

“…The multidrug resistant bacterium Acinetobacter baumannii is a significant cause of nosocomial infection. Biofilm formation, that requires both disulfide bond…”
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Identifying ligand-binding hot spots in proteins using brominated fragments by Grøftehauge, Morten K., Therkelsen, Martin Ø., Taaning, Rolf, Skrydstrup, Troels, Morth, J. Preben, Nissen, Poul

“…High‐quality crystals of Thermus thermophilus EF‐Tu in the GTP‐bound conformation at 1.7–2.7 Å resolution were used to test 18 small organic molecules, all…”
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Ligands bind to Sortilin in the tunnel of a ten-bladed β-propeller domain by Petersen, Claus M, Thirup, Søren S, Quistgaard, Esben M, Madsen, Peder, Grøftehauge, Morten K, Nissen, Poul

“…The structure of the Sortilin ectodomain in complex with neurotensin has been determined at 2-Å resolution, revealing that the C-terminal part of neurotensin…”
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Revisiting the structure of the Vps10 domain of human sortilin and its interaction with neurotensin by Quistgaard, Esben M., Grøftehauge, Morten K., Madsen, Peder, Pallesen, Lone T., Christensen, Brian, Sørensen, Esben S., Nissen, Poul, Petersen, Claus M., Thirup, Søren S.

“…Sortilin is a multifunctional receptor involved in sorting and apoptosis. We have previously reported a 2.0‐Å structure of the Vps10 ectodomain in complex with…”
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Crystal Structure of a Hidden Protein, YcaC, a Putative Cysteine Hydrolase from Pseudomonas aeruginosa, with and without an Acrylamide Adduct by Grøftehauge, Morten K, Truan, Daphne, Vasil, Adriana, Denny, Paul W, Vasil, Michael L, Pohl, Ehmke

“…As part of the ongoing effort to functionally and structurally characterize virulence factors in the opportunistic pathogen Pseudomonas aeruginosa, we…”
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Ligands bind to Sortilin in the tunnel of a ten-bladed [beta]-propeller domain by Quistgaard, Esben M, Madsen, Peder, Grøftehauge, Morten K, Nissen, Poul, Petersen, Claus M, Thirup, Søren S

“…The structure of the Sortilin ectodomain in complex with neurotensin has been determined at 2 angstroms resolution, revealing that the C-terminal part of…”
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