Search Results - "Grönke L"

The efficacy and safety of combined tiotropium and olodaterol via the Respimat(®) inhaler in patients with COPD: results from the Japanese sub-population of the Tonado(®) studies by Ichinose, Masakazu, Taniguchi, Hiroyuki, Takizawa, Ayako, Grönke, Lars, Loaiza, Lazaro, Voß, Florian, Zhao, Yihua, Fukuchi, Yoshinosuke

“…The efficacy and safety of once-daily tiotropium + olodaterol (T+O) maintenance treatment was demonstrated in the large, multinational, replicate, randomized,…”
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Effects of baseline symptom burden on treatment response in COPD by Martinez, Fernando J, Abrahams, Roger A, Ferguson, Gary T, Bjermer, Leif, Grönke, Lars, Voß, Florian, Singh, Dave

“…In symptomatic patients with COPD, the decision whether to initiate maintenance treatment with a single agent or a combination of long-acting bronchodilators…”
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Efficacy and safety of tiotropium + olodaterol maintenance treatment in patients with COPD in the TONADO ® and OTEMTO ® studies: a subgroup analysis by age by Ferguson, Gary T, Karpel, Jill P, Clerisme-Beaty, Emmanuelle, Grönke, Lars, Voß, Florian, Buhl, Roland

“…Increasing age is associated with poor prognosis in patients with COPD. This analysis from the replicate Phase III OTEMTO and TONADO studies examined the…”
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Effect of the oral leukotriene B4 receptor antagonist LTB019 on inflammatory sputum markers in patients with chronic obstructive pulmonary disease by Grönke, L, Beeh, K.M, Cameron, R, Kornmann, O, Beier, J, Shaw, M, Holz, O, Buhl, R, Magnussen, H, Jörres, R.A

“…Abstract This study aimed to evaluate the effect of a LTB4 receptor antagonist on inflammatory markers in induced sputum, in particular sputum neutrophilia, in…”
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Interleukin-2 inhalation therapy temporarily induces asthma-like airway inflammation by Loppow, D, Huland, E, Heinzer, H, Grönke, L, Magnussen, H, Holz, O, Jörres, Rudolf A

“…Inhaled interleukin-2 (IL-2) is an effective and safe treatment in metastasing renal cell carcinoma (mRCC) but known to potentially elicit respiratory…”
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The diagnosis and management of chronic cough by Morice, A H, Fontana, G A, Sovijarvi, A R A, Pistolesi, M, Chung, K F, Widdicombe, J, O'Connell, F, Geppetti, P, Gronke, L, De Jongste, J, Belvisi, M, Dicpinigaitis, P, Fischer, A, McGarvey, L, Fokkens, W J, Kastelik, J

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The lung function profile of once-daily tiotropium and olodaterol via Respimat® is superior to that of twice-daily salmeterol and fluticasone propionate via Accuhaler® (ENERGITO® study) by Beeh, K M, Derom, E, Echave-Sustaeta, J, Grönke, L, Hamilton, A, Zhai, D, Bjermer, L

“…Background: Tiotropium + olodaterol has demonstrated improvements beyond lung function benefits in a large Phase III clinical program as a once-daily…”
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The relationship between airway hyper-responsiveness, markers of inflammation and lung function depends on the duration of the asthmatic disease by Grönke, L., Kanniess, F., Holz, O., Jörres, R. A., Magnussen, H.

“…Background The combination of airway hyper‐responsiveness, eosinophilic airway inflammation, and lung function impairment is considered as a hallmark of…”
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D36 ALL TOGETHER NOW: COPD TREATMENT WITH LONG-ACTING BETA AGONISTS AND LONG-ACTING MUSCARINIC ANTAGONISTS: Analysis Of The Efficacy And Safety Of The Fixed-Dose Combination Of Tiotropium + Olodaterol In Patients With COPD By Previous Usage Of Inhaled Corticosteroids by Korn, S, Buhl, R, Grönke, L, Korducki, L, Amatto, V C, Ferguson, G T, Abrahams, R

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The lung function profile of once-daily tiotropium and olodaterol via Respimat® is superior to that of twice-daily salmeterol and fluticasone propionate viaAccuhaler® (ENERGITO® study) by Beeh KM, Derom E, Echave-Sustaeta J, Grönke L, Hamilton A, Zhai D, Bjermer L

“…Kai-Michael Beeh,1 Eric Derom,2 José Echave-Sustaeta,3 Lars Grönke,4 Alan Hamilton,5 Dongmei Zhai,6 Leif Bjermer71Insaf GmbH Institut für Atemwegsforschung,…”
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Reproducibility of forced inspiratory and expiratory volumes after bronchodilation in patients with COPD or asthma by TAUBE, C, KANNIESS, F, GRÖNKE, L, RICHTER, K, MÜCKE, M, PAASCH, K, EICHLER, G, JÖRRES, R.A, MAGNUSSEN, H

“…The aim of the present study was to assess the reproducibility of changes in forced inspiratory volumes after bronchodilator inhalation. Thirteen patients with…”
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Effect of the oral leukotriene B 4 receptor antagonist LTB019 on inflammatory sputum markers in patients with chronic obstructive pulmonary disease by Grönke, L., Beeh, K.M., Cameron, R., Kornmann, O., Beier, J., Shaw, M., Holz, O., Buhl, R., Magnussen, H., Jörres, R.A.

“…This study aimed to evaluate the effect of a LTB 4 receptor antagonist on inflammatory markers in induced sputum, in particular sputum neutrophilia, in…”
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D36 COPD: LABA, LAMA, ICS, AND COMBINATIONS: Effect Of Tiotropium + Olodaterol Therapy On COPD Exacerbations In The Tonado® Studies by Derom, E, Flezar, M, Gronke, L, Vob, F, Buhl, R

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D36 COPD: LABA, LAMA, ICS, AND COMBINATIONS: Efficacy And Safety Of Tiotropium + Olodaterol In Patients With COPD By Ats Category by Maltais, F, Pizzichini, E, Gronke, L, Vob, F, Derom, E

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A short protocol for methacholine provocation testing adapted to the Rosenthal-Chai dosimeter technique by Jörres, R A, Nowak, D, Kirsten, D, Grönke, L, Magnussen, H

“…The purpose of this study was to develop a rapid and safe methacholine provocation protocol equivalent to the standard dosimeter technique. The rapid protocol…”
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D36 COPD: LABA, LAMA, ICS, AND COMBINATIONS: Tiotropium + Olodaterol Therapy Provides Lung-Function Benefits Over Salmeterol + Fluticasone Propionate Irrespective Of Prior Ics Treatment: Post Hoc Analyses Of The Energito® Study by Derom, E, Clerisme-Beaty, E, Gronke, L, Voss, F, Zhai, D, Bjermer, L

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C103 EOSINOPHILS IN COPD AND THE ASTHMA-COPD OVERLAP SYNDROME: SORTING THROUGH THE CHAOS OF ACOS: Is Blood Eosinophil Count A Predictor Of Disease Worsening after Ics Withdrawal? by Watz, H, Magnussen, H, Tetzlaff, K, Gronke, L, Finnigan, H, Calverley, P M

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D36 COPD: LABA, LAMA, ICS, AND COMBINATIONS: Benefits Of Tiotropium + Olodaterol On Symptoms And Health-Related Quality Of Life In Patients With Moderate To Severe COPD With Chronic Bronchitis And/or Emphysema by Ferguson, G T, Abrahams, R, Bjermer, L, Gronke, L, Vob, F, Singh, D

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D36 COPD: LABA, LAMA, ICS, AND COMBINATIONS: Tiotropium + Olodaterol Therapy Provides Symptomatic Benefits Irrespective Of Prior Maintenance Treatment: Post Hoc Analyses Of The Otemto® Studies by Abrahams, R, Ferguson, G T, Bjermer, L, Gronke, L, Vob, F, Singh, D

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D36 COPD: LABA, LAMA, ICS, AND COMBINATIONS: Benefits Of Tiotropium Versus Placebo For Delaying Clinically Significant Events In Patients With Moderate COPD (gold 2) by Rabe, K, Metzdorf, N, Vob, F, Hallmann, C, Gronke, L, Tashkin, D

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