Search Results - "Gröer, C."

LC–MS/MS-based quantification of clinically relevant intestinal uptake and efflux transporter proteins by Gröer, C., Brück, S., Lai, Y., Paulick, A., Busemann, A., Heidecke, C.D., Siegmund, W., Oswald, S.

“…•LC–MS/MS methods for ten drug transporters (ABCB1, ABCC2, ABCC3, ABCG2, OATP1A2, OATP2B1, PEPT1, ASBT, OCT1 and OCT3).•First quantitative assays for ABCC3,…”
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Absolute protein quantification of clinically relevant cytochrome P450 enzymes and UDP-glucuronosyltransferases by mass spectrometry-based targeted proteomics by Gröer, C., Busch, D., Patrzyk, M., Beyer, K., Busemann, A., Heidecke, C.D., Drozdzik, M., Siegmund, W., Oswald, S.

“…•Simultaneous LC–MS/MS-based quantification of 13 relevant metabolizing enzymes.•Comprehensive method validation for all aforementioned enzymes.•Application to…”
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An opioid agonist that does not induce mu-opioid receptor--arrestin interactions or receptor internalization by Groer, C E, Tidgewell, K, Moyer, R A, Harding, W W, Rothman, R B, Prisinzano, T E, Bohn, L M

“…G protein-coupled receptor desensitization and trafficking are important regulators of opioid receptor signaling that can dictate overall drug responsiveness…”
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Clinical characteristics and outcomes of invasively ventilated patients with COVID-19 in Argentina (SATICOVID): a prospective, multicentre cohort study by Ríos, Fernando G, Kanoore Edul, Vanina S, Plotnikow, Gustavo, Andrian, Macarena, Romero, Ignacio, Piezny, Damián, Bezzi, Marco, Torres, Sebastián, Orlandi, Cristina, Valenti, María F, Tiribelli, Norberto, Estenssoro, E, Dubin, A, Kanoore Edul, V S, Plotnikow, G, Andrian, M, Ivacachi, J, Piezny, D, Sagardía, J, Bezzi, M, Borello, S, Mandich, V, Chiacchiara, D, Kovac, A, Torres, S, Rubatto Birri, P N, Mugno, M, Gómez, R A, Cunto, E, Chediack, V, Marchena, C, Tiribelli, N, Guaymas, M, Aphalo, V, Vázquez, D, Sánchez, D, Iglesias, F, Casteluccio, P, Lattanzio, B, Noval, D, Fredes, S, Izzo, G C, Pozo, M O, Sac, S, Tornatore, N, Villafañe, C, Di Sibio, A, Rodríguez, P, Nihany, N, Esperatti, M, Pintos, J M, Badariotti, G, Echevarría, G, Mazzola, A M, Dargains, N, Turano, A, Pugliese, F, Zec Baskarad, M J, Chamadoira, M, Medina, J C, Villarejo, F, Collazos, H, Huanca, T, Pendino, J C, Talamonti, L, Skrzypiec, F, Genovese, G, Alul, H, Zavattieri, A, Rosales, N, Quintana, M G, Risso Vazquez, A, Lugaro, M, Díaz Rousseaux, E, Falcone, M, Kurban, F, Cini, M, Fernández, G, Barrios, S, Hamada, O, Mendiluce, V, Villalba, D, Mezzina, V, Servin, C, Quinteros, M, Banegas, D, Maicol, F, Barrientos, A, Larocca, F, Luna, R, Oholeguy, A, Carnero Echegaray, J, Marazzi, C, Helca Regis, P, Bobadilla, A, Villavicencio, C, Machare, P, González, C, Ferriccioni, M, Bergesio, J

“…Although COVID-19 has greatly affected many low-income and middle-income countries, detailed information about patients admitted to the intensive care unit…”
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Functional Selectivity of 6′-Guanidinonaltrindole (6′-GNTI) at κ-Opioid Receptors in Striatal Neurons by Schmid, Cullen L., Streicher, John M., Groer, Chad E., Munro, Thomas A., Zhou, Lei, Bohn, Laura M.

“…There is considerable evidence to suggest that drug actions at the κ-opioid receptor (KOR) may represent a means to control pain perception and modulate reward…”
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The Mathematics of Survival: From Antiquity to the Playground by Groer, Chris

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