Search Results - "Grémy, Olivier"

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    Excretion of Pu-238 during Long-term Chelation Therapy by Repeated DTPA Inhalation by Grémy, Olivier, Blanchin, Nicolas, Miccoli, Laurent

    Published in Health physics (1958) (01-09-2022)
    “…An individual underwent an extensive diethylenetriaminepentaacetate (DTPA) chelation therapy that started several months after plutonium incorporation, most…”
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    Journal Article
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    Interpretation of Enhanced Fecal and Urinary Plutonium Excretion Data under a 2-y Regular DTPA Treatment Started Months after Intake by Grémy, Olivier, Blanchin, Nicolas, Miccoli, Laurent

    Published in Health physics (1958) (01-11-2021)
    “…In a worker who had internalized plutonium, most likely through inhalation of a somewhat soluble compound, an extensive diethylenetriaminepentaacetate (DTPA)…”
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    Journal Article
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    Chelation therapy with 3,4,3-Li(1,2-HOPO) after pulmonary exposure to plutonium in rats by Grémy, Olivier, Devilliers, Karine, Miccoli, Laurent

    Published in Chemico-biological interactions (01-06-2023)
    “…Internal exposure to plutonium can occur through inhalation for the nuclear worker, but also for the public if the radionuclide was released into the…”
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    Journal Article
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    Activation of Alveolar Macrophages after Plutonium Oxide Inhalation in Rats: Involvement in the Early Inflammatory Response by Van der Meeren, Anne, Tourdes, Françoise, Grémy, Olivier, Grillon, Gérard, Abram, Marie-Claire, Poncy, Jean-Luc, Griffiths, Nina

    Published in Radiation research (01-11-2008)
    “…Van der Meeren, A., Tourdes, F., Grémy, O., Grillon, G., Abram, M-C., Poncy, J-L. and Griffiths, N. Activation of Alveolar Macrophages after Plutonium Oxide…”
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    Journal Article
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    Chelation Treatment by Early Inhalation of Liquid Aerosol DTPA for Removing Plutonium after Rat Lung Contamination by Miccoli, Laurent, Ménétrier, Florence, Laroche, Pierre, Grémy, Olivier

    Published in Radiation research (01-12-2019)
    “…Occupational contamination is a potential health risk associated with plutonium inhalation. DTPA remains the chelating drug of choice to decorporate plutonium…”
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    Journal Article
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    Chelation Modeling of a Plutonium-238 Inhalation Incident Treated with Delayed DTPA by Dumit, Sara, Miller, Guthrie, Grémy, Olivier, Poudel, Deepesh, Bertelli, Luiz, Klumpp, John A.

    Published in Radiation research (14-11-2023)
    “…This work describes an analysis, using a previously established chelation model, of the bioassay data collected from a worker who received delayed chelation…”
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  14. 14

    DTPA-Coated Liposomes as a New Delivery Vehicle for Plutonium Decorporation by Grémy, Olivier, Mougin-Degraef, Marie, Devilliers, Karine, Berdal, Marion, Laroche, Pierre, Miccoli, Laurent

    Published in Radiation research (01-01-2021)
    “…Administration of diethylenetriaminepentaacetic acid (DTPA) is the treatment approach used to promote the decorporation of internalized plutonium. Here we…”
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    Journal Article
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    Decorporation Approach after Rat Lung Contamination with Plutonium: Evaluation of the Key Parameters Influencing the Efficacy of a Protracted Chelation Treatment by Grémy, Olivier, Coudert, Sylvie, Renault, Daniel, Miccoli, Laurent

    Published in Radiation research (01-11-2017)
    “…While the efficacy of a protracted zinc (Zn)- or calcium (Ca)-diethylenetriaminepentaacetic acid (DTPA) treatment in reducing transuranic body burden has…”
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    Journal Article
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    Decorporation of Pu/Am Actinides by Chelation Therapy: New Arguments in Favor of an Intracellular Component of DTPA Action by Grémy, Olivier, Laurent, David, Coudert, Sylvie, Griffiths, Nina M., Miccoli, Laurent

    Published in Radiation research (01-06-2016)
    “…Diethylenetriaminepentaacetic acid (DTPA) is currently still the only known chelating drug that can be used for decorporation of internalized plutonium (Pu)…”
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    Journal Article
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    Delivery of DTPA through Liposomes as a Good Strategy for Enhancing Plutonium Decorporation Regardless of Treatment Regimen by Grémy, Olivier, Miccoli, Laurent, Lelan, Faustine, Bohand, Sandra, Cherel, Michel, Mougin-Degraef, Marie

    Published in Radiation research (01-05-2018)
    “…In this study, we assessed the efficacy of unilamellar 110-nm liposomes encapsulating the chelating agent diethylenetriaminepentaacetic acid (DTPA) in…”
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    Journal Article
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    Comparison of Local and Systemic DTPA Treatment Efficacy According to Actinide Physicochemical Properties Following Lung or Wound Contamination in the Rat by Griffiths, Nina M, Van der Meeren, Anne, Grémy, Olivier

    Published in Frontiers in pharmacology (26-03-2021)
    “…In cases of occupational accidents in nuclear facilities or subsequent to terrorist activities, the most likely routes of internal contamination with…”
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    Modelling DTPA therapy following Am contamination in rats by Kastl, Manuel, Grémy, Olivier, Lamart, Stephanie, Giussani, Augusto, Li, Wei Bo, Hoeschen, Christoph

    Published in Radiation and environmental biophysics (01-11-2023)
    “…A major challenge in modelling the decorporation of actinides (An), such as americium (Am), with DTPA (diethylenetriaminepentaacetic acid) is the fact that…”
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