Search Results - "Grélaud, Simon"

Branch-Selective and Enantioselective Iridium-Catalyzed Alkene Hydroarylation via Anilide-Directed C–H Oxidative Addition by Grélaud, Simon, Cooper, Phillippa, Feron, Lyman J, Bower, John F

“…Tertiary benzylic stereocenters are accessed in high enantioselectivity by Ir-catalyzed branch selective addition of anilide ortho-C–H bonds across styrenes…”
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Stereocontrolled (Me3Si)3SiH-Mediated Radical and Ionic Hydride Transfer in Synthesis of 2,3,5-Trisubstituted THF by Grélaud, Simon, Desvergnes, Valérie, Landais, Yannick

“…2,3,5-Trisubstituted tetrahydrofurans were prepared stereoselectively through a two-step process involving the addition of an acyl radical to a β-silyloxy…”
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Acyl Radical Addition to Activated Olefins: A Stereocontrolled Route to Polysubstituted Tetrahydrofurans and Lactones, and Application to the Total Synthesis of (+)‐No. 2106 A by Grélaud, Simon, Lusseau, Jonathan, Landais, Yannick

“…The addition of acyl radicals to α,β‐unsaturated esters, followed by acetalization and reduction of the resulting hemiacetal was shown to provide a…”
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Acyl Radical Addition onto Aza‐Baylis–Hillman Adducts: A Stereocontrolled Access to 2,3,5‐Trisubstituted Pyrrolidines by Grélaud, Simon, Lusseau, Jonathan, Massip, Stéphane, Landais, Yannick

“…Free‐radical addition of acyl radicals to chiral aza‐Baylis–Hillman adducts was shown to afford the corresponding 1,4‐amino ketones in good yields and good…”
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Atom and step economical synthesis of acyclic quaternary centers via iridium-catalyzed hydroarylative cross-coupling of 1,1-disubstituted alkenes by Cooper, Phillippa, Dalling, Andrew G, Farrar, Elliot H E, Aldhous, Timothy P, Grélaud, Simon, Lester, Eleanor, Feron, Lyman J, Kemmitt, Paul D, Grayson, Matthew N, Bower, John F

“…Quaternary benzylic centers are accessed with high atom and step economy by Ir-catalyzed alkene hydroarylation. These studies provide unique examples of the…”
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Stereocontrolled (Me 3 Si) 3 SiH-Mediated Radical and Ionic Hydride Transfer in Synthesis of 2,3,5-Trisubstituted THF by Grélaud, Simon, Desvergnes, Valérie, Landais, Yannick

“…Trisubstituted tetrahydrofurans were prepared stereoselectively through a two-step process, involving the addition of an acyl radical to a -silyloxy acrylic…”
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Atom and step economical synthesis of acyclic quaternary centers iridium-catalyzed hydroarylative cross-coupling of 1,1-disubstituted alkenes by Cooper, Phillippa, Dalling, Andrew G, Farrar, Elliot H. E, Aldhous, Timothy P, Grélaud, Simon, Lester, Eleanor, Feron, Lyman J, Kemmitt, Paul D, Grayson, Matthew N, Bower, John F

“…Quaternary benzylic centers are accessed with high atom and step economy by Ir-catalyzed alkene hydroarylation. These studies provide unique examples of the…”
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