Search Results - "Grégoire, Isabel Pombo"

Autophagy induction by the pathogen receptor CD46 by Joubert, Pierre-Emmanuel, Meiffren, Grégory, Grégoire, Isabel Pombo, Pontini, Guillemette, Richetta, Clémence, Flacher, Monique, Azocar, Olga, Vidalain, Pierre-Olivier, Vidal, Marc, Lotteau, Vincent, Codogno, Patrice, Rabourdin-Combe, Chantal, Faure, Mathias

“…Autophagy is a highly regulated self-degradative mechanism required at a basal level for intracellular clearance and recycling of cytoplasmic contents. Upon…”
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Autophagy and RNA virus interactomes reveal IRGM as a common target by Grégoire, Isabel Pombo, Rabourdin-Combe, Chantal, Faure, Mathias

“…Several intracellular pathogens have the ability to avoid or exploit the otherwise destructive process of autophagy. RNA viruses are constantly confronted with…”
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IRGM is a common target of RNA viruses that subvert the autophagy network by Grégoire, Isabel Pombo, Richetta, Clémence, Meyniel-Schicklin, Laurène, Borel, Sophie, Pradezynski, Fabrine, Diaz, Olivier, Deloire, Alexandre, Azocar, Olga, Baguet, Joël, Le Breton, Marc, Mangeot, Philippe E, Navratil, Vincent, Joubert, Pierre-Emmanuel, Flacher, Monique, Vidalain, Pierre-Olivier, André, Patrice, Lotteau, Vincent, Biard-Piechaczyk, Martine, Rabourdin-Combe, Chantal, Faure, Mathias

“…Autophagy is a conserved degradative pathway used as a host defense mechanism against intracellular pathogens. However, several viruses can evade or subvert…”
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The antiapoptotic effect of heme oxygenase-1 in endothelial cells involves the degradation of p38 alpha MAPK isoform by Silva, Gabriela, Cunha, Andreia, Grégoire, Isabel Pombo, Seldon, Mark P, Soares, Miguel P

“…Heme oxygenase-1 (HO-1) protects endothelial cells (EC) from undergoing apoptosis. This effect is mimicked by CO, generated via the catabolism of heme by HO-1…”
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Pathogen recognition by the cell surface receptor CD46 induces autophagy by Meiffren, Grégory, Joubert, Pierre-Emmanuel, Grégoire, Isabel Pombo, Codogno, Patrice, Rabourdin-Combe, Chantal, Faure, Mathias

“…Autophagy is a degradative mechanism involved in cell protection against invading pathogens. Although the autophagic process is well characterized, the…”
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Heme oxygenase-1 expression enhances vascular endothelial resistance to complement-mediated injury through induction of decay-accelerating factor: a role for increased bilirubin and ferritin by Kinderlerer, Anne R., Pombo Gregoire, Isabel, Hamdulay, Shahir S., Ali, Faisal, Steinberg, Rivka, Silva, Gabriela, Ali, Nadira, Wang, Bufei, Haskard, Dorian O., Soares, Miguel P., Mason, Justin C.

“…Catabolism of free heme by heme oxygenase-1 (HO-1) generates carbon monoxide, biliverdin, and free iron (Fe). These end-products are responsible for much of…”
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Autophagy and pathogens: «Bon appétit Messieurs! by Joubert, Pierre-Emmanuel, Pombo Grégoire, Isabel, Meiffren, Grégory, Rabourdin-Combe, Chantal, Faure, Mathias

“…Autophagy is a highly conserved, self-degradative pathway for clearance and recycling of cytoplasmic contents. This ubiquitous cell intrinsic process can be…”
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The Legionella Kinase LegK2 Targets the ARP2/3 Complex To Inhibit Actin Nucleation on Phagosomes and Allow Bacterial Evasion of the Late Endocytic Pathway by Michard, Céline, Sperandio, Daniel, Baïlo, Nathalie, Pizarro-Cerdá, Javier, LeClaire, Lawrence, Chadeau-Argaud, Elise, Pombo-Grégoire, Isabel, Hervet, Eva, Vianney, Anne, Gilbert, Christophe, Faure, Mathias, Cossart, Pascale, Doublet, Patricia

“…Legionella pneumophila, the etiological agent of legionellosis, replicates within phagocytic cells. Crucial to biogenesis of the replicative vacuole is the…”
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Heme oxygenase-1 and carbon monoxide suppress the pathogenesis of experimental cerebral malaria by Soares, Miguel P, Mota, Maria M, Pamplona, Ana, Ferreira, Ana, Balla, József, Jeney, Viktória, Balla, György, Epiphanio, Sabrina, Chora, Ângelo, Rodrigues, Cristina D, Gregoire, Isabel Pombo, Cunha-Rodrigues, Margarida, Portugal, Silvia

“…Cerebral malaria claims more than 1 million lives per year. We report that heme oxygenase-1 (HO-1, encoded by Hmox1) prevents the development of experimental…”
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The italic toggle="yes">Legionella /italic> Kinase LegK2 Targets the ARP2/3 Complex To Inhibit Actin Nucleation on Phagosomes and Allow Bacterial Evasion of the Late Endocytic Pathway by Céline Michard, Daniel Sperandio, Nathalie Baïlo, Javier Pizarro-Cerdá, Lawrence LeClaire, Elise Chadeau-Argaud, Isabel Pombo-Grégoire, Eva Hervet, Anne Vianney, Christophe Gilbert, Mathias Faure, Pascale Cossart, Patricia Doublet

“…ABSTRACT Legionella pneumophila, the etiological agent of legionellosis, replicates within phagocytic cells. Crucial to biogenesis of the replicative vacuole…”
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Heme Oxygenase-1 Inhibits the Expression of Adhesion Molecules Associated with Endothelial Cell Activation via Inhibition of NF-κB RelA Phosphorylation at Serine 276 by Seldon, Mark P., Silva, Gabriela, Pejanovic, Nadja, Larsen, Rasmus, Gregoire, Isabel Pombo, Filipe, Josina, Anrather, Josef, Soares, Miguel P.

“…Abstract Heme oxygenase-1 (HO-1; encoded by the Hmox1 gene) catalyzes the degradation of free heme into biliverdin, via a reaction that releases iron (Fe) and…”
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Heme Oxygenase-1 Modulates the Expression of Adhesion Molecules Associated with Endothelial Cell Activation by Soares, Miguel P, Seldon, Mark P, Gregoire, Isabel Pombo, Vassilevskaia, Tatiana, Berberat, Pascal O, Yu, Jia, Tsui, Tung-Yu, Bach, Fritz H

“…Heme oxygenase-1 (HO-1) cleaves the porphyrin ring of heme into carbon monoxide, Fe2+, and biliverdin, which is then converted into bilirubin. Heme-derived…”
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Heme oxygenase-1 inhibits the expression of adhesion molecules associated with endothelial cell activation via inhibition of NF-kappaB RelA phosphorylation at serine 276 by Seldon, Mark P, Silva, Gabriela, Pejanovic, Nadja, Larsen, Rasmus, Gregoire, Isabel Pombo, Filipe, Josina, Anrather, Josef, Soares, Miguel P

“…Heme oxygenase-1 (HO-1; encoded by the Hmox1 gene) catalyzes the degradation of free heme into biliverdin, via a reaction that releases iron (Fe) and carbon…”
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Heme Oxygenase-1 Inhibits the Expression of Adhesion Molecules Associated with Endothelial Cell Activation via Inhibition of NF-{kappa}B RelA Phosphorylation at Serine 276 by Seldon, Mark P, Silva, Gabriela, Pejanovic, Nadja, Larsen, Rasmus, Gregoire, Isabel Pombo, Filipe, Josina, Anrather, Josef, Soares, Miguel P

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The Antiapoptotic Effect of Heme Oxygenase-1 in Endothelial Cells Involves the Degradation of p38{alpha} MAPK Isoform by Silva, Gabriela, Cunha, Andreia, Gregoire, Isabel Pombo, Seldon, Mark P, Soares, Miguel P

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