Search Results - "Gräbner, Rolf"

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    Genetic and pharmacological inhibition of the 5-lipoxygenase/leukotriene pathway in atherosclerotic lesion development in ApoE deficient mice by Cao, Richard Yang, St. Amand, Tim, Gräbner, Rolf, Habenicht, Andreas J.R, Funk, Colin D

    Published in Atherosclerosis (01-04-2009)
    “…Abstract The 5-lipoxygenase (5-LO) catalyzed formation of leukotriene (LT) lipid mediators is a pathway contributing to inflammatory events in asthma and more…”
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    Journal Article
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    Control of dichotomic innate and adaptive immune responses by artery tertiary lymphoid organs in atherosclerosis by Weih, Falk, Gräbner, Rolf, Hu, Desheng, Beer, Michael, Habenicht, Andreas J R

    Published in Frontiers in physiology (01-01-2012)
    “…Tertiary lymphoid organs (TLOs) emerge in tissues in response to non-resolving inflammation such as chronic infection, graft rejection, and autoimmune disease…”
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    The Lamina Adventitia Is the Major Site of Immune Cell Accumulation in Standard Chow-Fed Apolipoprotein E–Deficient Mice by Moos, Michael P.W, John, Nicole, Gräbner, Rolf, Nomann, Silke, Günther, Bernd, Vollandt, Rüdiger, Funk, Colin D, Kaiser, Brigitte, Habenicht, Andreas J.R

    “…OBJECTIVE—Cells of adaptive immunity have been implicated in atherogenesis. Though substantial information is available on immune cells in atherosclerotic…”
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    The 5-lipoxygenase pathway promotes pathogenesis of hyperlipidemia-dependent aortic aneurysm by Funk, Colin D, Zhao, Lei, Moos, Michael P W, Gräbner, Rolf, Pédrono, Frédérique, Fan, Jinjin, Kaiser, Brigitte, John, Nicole, Schmidt, Sandra, Spanbroek, Rainer, Lötzer, Katharina, Huang, Li, Cui, Jisong, Rader, Daniel J, Evans, Jilly F, Habenicht, Andreas J R

    Published in Nature medicine (01-09-2004)
    “…Activation of the 5-lipoxygenase (5-LO) pathway leads to the biosynthesis of proinflammatory leukotriene lipid mediators. Genetic studies have associated 5-LO…”
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    l-Ascorbic Acid Potentiates Nitric Oxide Synthesis in Endothelial Cells by Heller, R, Münscher-Paulig, F, Gräbner, R, Till, U

    Published in The Journal of biological chemistry (19-03-1999)
    “…Ascorbic acid has been shown to enhance impaired endothelium-dependent vasodilation in patients with atherosclerosis by a mechanism that is thought to involve…”
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    Hypochlorite-modified Low Density Lipoprotein Inhibits Nitric Oxide Synthesis in Endothelial Cells via an Intracellular Dislocalization of Endothelial Nitric-oxide Synthase by Nuszkowski, A, Gräbner, R, Marsche, G, Unbehaun, A, Malle, E, Heller, R

    Published in The Journal of biological chemistry (27-04-2001)
    “…Hypochlorous acid/hypochlorite, generated by the myeloperoxidase/H 2 O 2 /halide system of activated phagocytes, has been shown to oxidize/modify low density…”
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    Influence of cationic amphiphilic drugs on the phosphatidylcholine hydrolysis by phospholipase A2 by Gräbner, R

    Published in Biochemical pharmacology (01-04-1987)
    “…On chronic treatment certain amphiphilic drugs induce a generalized phospholipidosis. This drug side effect has been related to an inhibition of the lysosomal…”
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    Flow cytometric determination of E‐selectin, vascular cell adhesion molecule‐1, and intercellular cell adhesion molecule‐1 in formaldehyde‐fixed endothelial cell monolayers by Gräbner, Rolf, Till, Uwe, Heller, Regine

    Published in Cytometry (New York, N.Y.) (01-07-2000)
    “…Background Endothelial cell adhesion molecules are involved in initiation and progression of vascular diseases. The purpose of this study was to determine…”
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    Laser-capture microdissection of hyperlipidemic/ApoE⁻/⁻ mouse aorta atherosclerosis by Beer, Michael, Doepping, Sandra, Hildner, Markus, Weber, Gabriele, Grabner, Rolf, Hu, Desheng, Mohanta, Sarajo Kumar, Srikakulapu, Prasad, Weih, Falk, Habenicht, Andreas J R

    “…Atherosclerosis is a transmural chronic inflammatory condition of small and large arteries that is associated with adaptive immune responses at all disease…”
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    Incorporation in liposomes as a method for the application of genotoxins of low water solubility in the SCE assay by Thust, R, Gräbner, R

    Published in Mutation research (01-01-1984)
    “…Benzo[alpha]pyrene BaP), freely dissolved or incorporated in liposomes prepared from egg yolk lecithin, was checked for SCE induction in Chinese hamster V79-E…”
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