Search Results - "Gozoh Tsujimoto"

Maternal gut microbiota in pregnancy influences offspring metabolic phenotype in mice by Kimura, Ikuo, Miyamoto, Junki, Ohue-Kitano, Ryuji, Watanabe, Keita, Yamada, Takahiro, Onuki, Masayoshi, Aoki, Ryo, Isobe, Yosuke, Kashihara, Daiji, Inoue, Daisuke, Inaba, Akihiko, Takamura, Yuta, Taira, Satsuki, Kumaki, Shunsuke, Watanabe, Masaki, Ito, Masato, Nakagawa, Fumiyuki, Irie, Junichiro, Kakuta, Hiroki, Shinohara, Masakazu, Iwatsuki, Ken, Tsujimoto, Gozoh, Ohno, Hiroaki, Arita, Makoto, Itoh, Hiroshi, Hase, Koji

“…Antibiotics and dietary habits can affect the gut microbial community, thus influencing disease susceptibility. Although the effect of microbiota on the…”
Get full text

Role of free fatty acid receptors in the regulation of energy metabolism by Hara, Takafumi, Kashihara, Daiji, Ichimura, Atsuhiko, Kimura, Ikuo, Tsujimoto, Gozoh, Hirasawa, Akira

“…Free fatty acids (FFAs) are energy-generating nutrients that act as signaling molecules in various cellular processes. Several orphan G protein-coupled…”
Get full text

The short chain fatty acid receptor GPR43 regulates inflammatory signals in adipose tissue M2-type macrophages by Nakajima, Akira, Nakatani, Akiho, Hasegawa, Sae, Irie, Junichiro, Ozawa, Kentaro, Tsujimoto, Gozoh, Suganami, Takayoshi, Itoh, Hiroshi, Kimura, Ikuo

“…The regulation of inflammatory responses within adipose tissue by various types of immune cells is closely related to tissue homeostasis and progression of…”
Get full text

Short-chain fatty acids and ketones directly regulate sympathetic nervous system via G protein-coupled receptor 41 (GPR41) by Kimura, Ikuo, Inoue, Daisuke, Maeda, Takeshi, Hara, Takafumi, Ichimura, Atsuhiko, Miyauchi, Satoshi, Kobayashi, Makio, Hirasawa, Akira, Tsujimoto, Gozoh

“…The maintenance of energy homeostasis is essential for life, and its dysregulation leads to a variety of metabolic disorders. Under a fed condition, mammals…”
Get full text

Ketone body receptor GPR43 regulates lipid metabolism under ketogenic conditions by Miyamoto, Junki, Ohue-Kitano, Ryuji, Mukouyama, Hiromi, Nishida, Akari, Watanabe, Keita, Igarashi, Miki, Irie, Junichiro, Tsujimoto, Gozoh, Satoh-Asahara, Noriko, Itoh, Hiroshi, Kimura, Ikuo

“…Ketone bodies, including β-hydroxybutyrate and acetoacetate, are important alternative energy sources during energy shortage. β-Hydroxybutyrate also acts as a…”
Get full text

Mice Genetically Deficient in Vasopressin V1a and V1b Receptors Are Resistant to Jet Lag by Yamaguchi, Yoshiaki, Suzuki, Toru, Mizoro, Yasutaka, Kori, Hiroshi, Okada, Kazuki, Chen, Yulin, Fustin, Jean-Michel, Yamazaki, Fumiyoshi, Mizuguchi, Naoki, Zhang, Jing, Dong, Xin, Tsujimoto, Gozoh, Okuno, Yasushi, Doi, Masao, Okamura, Hitoshi

“…Jet-lag symptoms arise from temporal misalignment between the internal circadian clock and external solar time. We found that circadian rhythms of behavior…”
Get full text

Genome-wide analysis of aberrant methylation in human breast cancer cells using methyl-DNA immunoprecipitation combined with high-throughput sequencing by Ruike, Yoshinao, Imanaka, Yukako, Sato, Fumiaki, Shimizu, Kazuharu, Tsujimoto, Gozoh

“…Cancer cells undergo massive alterations to their DNA methylation patterns that result in aberrant gene expression and malignant phenotypes. However, the…”
Get full text

How reliable are G-protein-coupled receptor antibodies? by Michel, Martin C., Wieland, Thomas, Tsujimoto, Gozoh

“…A cluster of manuscripts in this issue of the Journal highlights a lack of selectivity of 49 antibodies against 19 subtypes of α 1 - and β-adrenoceptors,…”
Get full text

The SCFA Receptor GPR43 and Energy Metabolism by Kimura, Ikuo, Inoue, Daisuke, Hirano, Kanako, Tsujimoto, Gozoh

“…Free fatty acids (FFAs) are essential nutrients and act as signaling molecules in various cellular processes via binding with FFA receptors. Of these…”
Get full text

Trastuzumab produces therapeutic actions by upregulating miR-26a and miR-30b in breast cancer cells by Ichikawa, Takehiro, Sato, Fumiaki, Terasawa, Kazuya, Tsuchiya, Soken, Toi, Masakazu, Tsujimoto, Gozoh, Shimizu, Kazuharu

“…Trastuzumab has been used for the treatment of HER2-positive breast cancer (BC). However, a subset of BC patients exhibited resistance to trastuzumab therapy…”
Get full text

Dysfunction of lipid sensor GPR120 leads to obesity in both mouse and human by Ichimura, Atsuhiko, Hirasawa, Akira, Poulain-Godefroy, Odile, Bonnefond, Amélie, Hara, Takafumi, Yengo, Loïc, Kimura, Ikuo, Leloire, Audrey, Liu, Ning, Iida, Keiko, Choquet, Hélène, Besnard, Philippe, Lecoeur, Cécile, Vivequin, Sidonie, Ayukawa, Kumiko, Takeuchi, Masato, Ozawa, Kentaro, Tauber, Maithé, Maffeis, Claudio, Morandi, Anita, Buzzetti, Raffaella, Elliott, Paul, Pouta, Anneli, Jarvelin, Marjo-Riitta, Körner, Antje, Kiess, Wieland, Pigeyre, Marie, Caiazzo, Roberto, Van Hul, Wim, Van Gaal, Luc, Horber, Fritz, Balkau, Beverley, Lévy-Marchal, Claire, Rouskas, Konstantinos, Kouvatsi, Anastasia, Hebebrand, Johannes, Hinney, Anke, Scherag, Andre, Pattou, François, Meyre, David, Koshimizu, Taka-aki, Wolowczuk, Isabelle, Tsujimoto, Gozoh, Froguel, Philippe

“…Mice deficient in the lipid sensor GPR120 develop obesity, glucose intolerance and fatty liver when fed a high-fat diet, and a loss-of-function variant in the…”
Get full text

MicroRNA-210 Regulates Cancer Cell Proliferation through Targeting Fibroblast Growth Factor Receptor-like 1 (FGFRL1) by Tsuchiya, Soken, Fujiwara, Takeshi, Sato, Fumiaki, Shimada, Yutaka, Tanaka, Eiji, Sakai, Yoshiharu, Shimizu, Kazuharu, Tsujimoto, Gozoh

“…The importance of microRNAs (miRNAs) in human malignancies has been well recognized. Here, we report that the expression of microRNA-210 (miR-210) is…”
Get full text

Intra-platform repeatability and inter-platform comparability of microRNA microarray technology by Sato, Fumiaki, Tsuchiya, Soken, Terasawa, Kazuya, Tsujimoto, Gozoh

“…Over the last decade, DNA microarray technology has provided a great contribution to the life sciences. The MicroArray Quality Control (MAQC) project…”
Get full text

miRNAs and regulation of cell signaling by Ichimura, Atsuhiko, Ruike, Yoshinao, Terasawa, Kazuya, Tsujimoto, Gozoh

“…MicroRNAs (miRNAs) regulate gene expression post-transcriptionally by binding to target mRNAs in a sequence-specific manner. A large number of genes appear to…”
Get full text

Identification of novel microRNA targets based on microRNA signatures in bladder cancer by Ichimi, Takahiro, Enokida, Hideki, Okuno, Yasushi, Kunimoto, Ryo, Chiyomaru, Takeshi, Kawamoto, Ken, Kawahara, Kazuya, Toki, Kazuki, Kawakami, Kazumori, Nishiyama, Kenryu, Tsujimoto, Gozoh, Nakagawa, Masayuki, Seki, Naohiko

“…MicroRNAs (miRNAs) are small noncoding RNAs that negatively regulate protein‐coding genes. To identify miRNAs that have a tumor suppressive function in bladder…”
Get full text

Free fatty acid receptors act as nutrient sensors to regulate energy homeostasis by Ichimura, Atsuhiko, Hirasawa, Akira, Hara, Takafumi, Tsujimoto, Gozoh

“…Free fatty acids (FFAs) have been demonstrated to act as ligands of several G-protein-coupled receptors (GPCRs) (FFAR1, FFAR2, FFAR3, GPR84, and GPR120). These…”
Get full text

MicroRNA-141 confers resistance to cisplatin-induced apoptosis by targeting YAP1 in human esophageal squamous cell carcinoma by Imanaka, Yukako, Tsuchiya, Soken, Sato, Fumiaki, Shimada, Yutaka, Shimizu, Kazuharu, Tsujimoto, Gozoh

“…MicroRNAs (miRNAs) are endogenous non-coding RNAs that function as negative regulators of gene expression. Alterations in miRNA expression have been shown to…”
Get full text

Free fatty acid receptors FFAR1 and GPR120 as novel therapeutic targets for metabolic disorders by Hara, Takafumi, Hirasawa, Akira, Ichimura, Atsuhiko, Kimura, Ikuo, Tsujimoto, Gozoh

“…Free fatty acids (FFAs) are not only essential nutritional components, but they also act as signaling molecules in various physiological processes. Recently, a…”
Get more information

Free fatty acids regulate gut incretin glucagon-like peptide-1 secretion through GPR120 by Tsujimoto, Gozoh, Hirasawa, Akira, Tsumaya, Keiko, Awaji, Takeo, Katsuma, Susumu, Adachi, Tetsuya, Yamada, Masateru, Sugimoto, Yukihiko, Miyazaki, Shunichi

“…Diabetes, a disease in which the body does not produce or use insulin properly, is a serious global health problem. Gut polypeptides secreted in response to…”
Get full text

MicroRNA-34a inhibits cell proliferation by repressing mitogen-activated protein kinase kinase 1 during megakaryocytic differentiation of K562 cells by Ichimura, Atsuhiko, Ruike, Yoshinao, Terasawa, Kazuya, Shimizu, Kazuharu, Tsujimoto, Gozoh

“…Phorbol 12-myristate 13-acetate (PMA) induces megakaryocytic differentiation of the human chronic myelocytic leukemia cell line K562. We examined the potential…”
Get more information