Search Results - "Gozlan, Yosi Meir"

Avidity optimization of a MAGE‐A1‐specific TCR with somatic hypermutation by Bassan, David, Gozlan, Yosi Meir, Sharbi‐Yunger, Adi, Tzehoval, Esther, Greenstein, Erez, Bitan, Lidor, Friedman, Nir, Eisenbach, Lea

“…A T‐cell receptor (TCR) with optimal avidity to a tumor antigen can be used to redirect T cells to eradicate cancer cells via adoptive cell transfer. Cancer…”
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Optimizing T‐cell receptor avidity with somatic hypermutation by Bassan, David, Gozlan, Yosi Meir, Sharbi‐Yunger, Adi, Tzehoval, Esther, Eisenbach, Lea

“…Adoptive transfer of T cells that have been genetically modified to express an antitumor T‐cell receptor (TCR) is a potent immunotherapy, but only if TCR…”
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CTLA4-FasL, the Hexameric Targeted FasL Fusion Protein, As Potential Novel Treatment for DLBCL by Aronin, Alexandra, Ben Gigi-Tamir, Liat, Makdasi, Efi, Amsili, Shira, Ben David, Shlomi, Avraham, Ortal, Sagiv, Yehudith Jitka, Gozlan, Yosi Meir, Shani, Noam, Dranitzki Elhalel, Michal

“…The bi-functional drug CTLA4-FasL (KAHR-102) is a fusion protein composed of the extracellular domains of CTLA4 and FasL. It naturally forms a stable…”
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Toxicology and Pharmacokinetic Studies in Mice and Nonhuman Primates of the Nontoxic, Efficient, Targeted Hexameric FasL: CTLA4-FasL by Makdasi, Efi, Amsili, Shira, Aronin, Alexandra, Prigozhina, Tatyana B, Tzdaka, Kobi, Gozlan, Yosi Meir, Ben Gigi-Tamir, Liat, Sagiv, Jitka Yehudith, Shkedy, Fanny, Shani, Noam, Tykocinski, Mark L, Dranitzki Elhalel, Michal

“…Cytotoxic T-lymphocyte antigen 4 (CTLA4)-FasL, a homo-hexameric signal converter protein, is capable of inducing robust apoptosis in malignant cells of the…”
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T Cell Receptor Affinity Maturation by Somatic Hypermutation by Gozlan, Yosi Meir

“…Adoptive cell transfer (ACT) of tumor specific T lymphocytes, after host immunodepletion, was shown to mediate objective cancer regression of metastatic…”
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