Search Results - "Gozen, Oguz"

Novel regulation mechanism of adrenal cortisol and DHEA biosynthesis via the endogen ERAD inhibitor small VCP-interacting protein by Ilhan, Recep, Üner, Göklem, Yilmaz, Sinem, Atalay Sahar, Esra, Cayli, Sevil, Erzurumlu, Yalcin, Gozen, Oguz, Ballar Kirmizibayrak, Petek

“…Endoplasmic reticulum-associated degradation (ERAD) is a well-characterized mechanism of protein quality control by removal of misfolded or unfolded proteins…”
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Presynaptic Regulation of Astroglial Excitatory Neurotransmitter Transporter GLT1 by Yang, Yongjie, Gozen, Oguz, Watkins, Andrew, Lorenzini, Ileana, Lepore, Angelo, Gao, Yuanzheng, Vidensky, Svetlana, Brennan, Jean, Poulsen, David, Won Park, Jeong, Li Jeon, Noo, Robinson, Michael B., Rothstein, Jeffrey D.

“…The neuron-astrocyte synaptic complex is a fundamental operational unit of the nervous system. Astroglia regulate synaptic glutamate, via neurotransmitter…”
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Enhanced Novel Object Recognition and Spatial Memory in Rats Selectively Bred for High Nicotine Preference by Bekci, Eren, Gokmen, Ramazan Can, Kanit, Lutfiye, Gozen, Oguz, Balkan, Burcu, Koylu, Ersin O, Keser, Aysegul

“…This study examined the influence of genetic background on cognitive performance in a selectively bred high nicotine-preferring (NP) rat line. Using the novel…”
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Epigenetic regulation of neuron-dependent induction of astroglial synaptic protein GLT1 by Yang, Yongjie, Gozen, Oguz, Vidensky, Svetlana, Robinson, Michael B., Rothstein, Jeffrey D.

“…Astroglial glutamate transporter EAAT2/GLT1 prevents glutamate‐induced excitotoxicity in the central nervous system. Expression of EAAT2/GLT1 is dynamically…”
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Chronic Nicotine Consumption and Withdrawal Regulate Melanocortin Receptor, CRF, and CRF Receptor mRNA Levels in the Rat Brain by Gozen, Oguz, Aypar, Buket, Ozturk Bintepe, Meliha, Tuzcu, Fulya, Balkan, Burcu, Koylu, Ersin O, Kanit, Lutfiye, Keser, Aysegul

“…Alterations in the various neuropeptide systems in the mesocorticolimbic circuitry have been implicated in negative effects associated with drug withdrawal…”
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The epigenetic effect of nicotine on dopamine D1 receptor expression in rat prefrontal cortex by Gozen, Oguz, Balkan, Burcu, Yildirim, Emre, Koylu, Ersin O., Pogun, Sakire

“…ABSTRACT Nicotine is a highly addictive drug and exerts its effect partially through causing dopamine release, thereby increasing intrasynaptic dopamine levels…”
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Glutamate mediates platelet activation through the AMPA receptor by Morrell, Craig N, Sun, Henry, Ikeda, Masahiro, Beique, Jean-Claude, Swaim, Anne Marie, Mason, Emily, Martin, Tanika V, Thompson, Laura E, Gozen, Oguz, Ampagoomian, David, Sprengel, Rolf, Rothstein, Jeffrey, Faraday, Nauder, Huganir, Richard, Lowenstein, Charles J

“…Glutamate is an excitatory neurotransmitter that binds to the kainate receptor, the N-methyl-D-aspartate (NMDA) receptor, and the…”
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Electrochemical based detection of microRNA, mir21 in breast cancer cells by Kilic, Tugba, Topkaya, Seda Nur, Ozkan Ariksoysal, Dilsat, Ozsoz, Mehmet, Ballar, Petek, Erac, Yasemin, Gozen, Oguz

“…In this work, a novel electrochemical microRNA (miRNA) detection method based on enzyme amplified biosensing of mir21 from cell lysate of total RNA was…”
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Divergent Modulation of Proteostasis in Prostate Cancer by Ballar Kirmizibayrak, Petek, Erbaykent-Tepedelen, Burcu, Gozen, Oguz, Erzurumlu, Yalcin

“…Proteostasis regulates key cellular processes such as cell proliferation, differentiation, transcription, and apoptosis. The mechanisms by which proteostasis…”
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Decreased anxiety-like behavior in a selectively bred high nicotine-preferring rat line by Bayoglu, Merve, Ozturk Bintepe, Meliha, Kanit, Lutfiye, Balkan, Burcu, Gozen, Oguz, Koylu, Ersin O., Keser, Aysegul

“…Genetic vulnerability contributes significantly to the individual variability observed in nicotine dependence. Selective breeding for sensitivity to a…”
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Chronic nicotine‐induced changes in gene expression of delta and kappa‐opioid receptors and their endogenous ligands in the mesocorticolimbic system of the rat by Ugur, Muzeyyen, Kaya, Egemen, Gozen, Oguz, Koylu, Ersin O., Kanit, Lutfiye, Keser, Aysegul, Balkan, Burcu

“…Delta and kappa opioid receptors (DOR and KOR, respectively) and their endogenous ligands, proenkephalin (PENK) and prodynorphin (PDYN)‐derived opioid peptides…”
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A unique IBMPFD-related P97/VCP mutation with differential binding pattern and subcellular localization by Erzurumlu, Yalcin, Aydin Kose, Fadime, Gozen, Oguz, Gozuacik, Devrim, Toth, Eric A., Ballar, Petek

“…p97/VCP is a hexameric AAA type ATPase that functions in a variety of cellular processes such as endoplasmic reticulum associated degradation (ERAD), organelle…”
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Nicotinic cholinergic and dopaminergic receptor mRNA expression in male and female rats with high or low preference for nicotine by Gozen, Oguz, Nesil, Tanseli, Kanit, Lutfiye, Koylu, Ersin O., Pogun, Sakire

“…Background: Nicotine exerts its central actions through nicotinic acetylcholine receptors (nAChRs), which in turn regulate major neurotransmitter systems…”
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Nicotine regulates cocaine-amphetamine-Regulated Transcript (Cart) in the mesocorticolimbic system by Kaya, Egemen, Gozen, Oguz, Ugur, Muzeyyen, Koylu, Ersin O., Kanit, Lutfiye, Balkan, Burcu

“…ABSTRACT Cocaine‐and‐Amphetamine Regulated Transcript (CART) mRNA and peptides are intensely expressed in the brain regions comprising mesocorticolimbic…”
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Gene expression of pro-opiomelanocortin and melanocortin receptors is regulated in the hypothalamus and mesocorticolimbic system following nicotine administration by Tapinc, Damla E., Ilgin, Rabia, Kaya, Egemen, Gozen, Oguz, Ugur, Muzeyyen, Koylu, Ersin O., Kanit, Lutfiye, Keser, Aysegul, Balkan, Burcu

“…•0.6mg/kg nicotine increased POMC mRNA in the hypothalamus.•0.6mg/kg nicotine increased MC4R mRNA in the medial prefrontal cortex.•0.2, 0.4 and 0.6mg/kg…”
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Chronic oral nicotine administration and withdrawal regulate the expression of neuropeptide Y and its receptors in the mesocorticolimbic system by Birdogan, Ali, Salur, Elif, Tuzcu, Fulya, Gokmen, Ramazan C., Ozturk Bintepe, Meliha, Aypar, Buket, Keser, Aysegul, Balkan, Burcu, Koylu, Ersin O., Kanit, Lutfiye, Gozen, Oguz

“…Neuropeptide Y (NPY) and its receptors are involved in the regulation of mood, stress, and anxiety. In parallel, NPY signaling may play a vital role in the…”
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Chronic nicotine-induced changes in gene expression of delta and kappa-opioid receptors and their endogenous ligands in the mesocorticolimbic system of the rat: UGUR et al by Ugur, Muzeyyen, Kaya, Egemen, Gozen, Oguz, Koylu, Ersin O., Kanit, Lutfiye, Keser, Aysegul, Balkan, Burcu

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Hippocampal neuronal nitric oxide synthase (nNOS) is regulated by nicotine and stress in female but not in male rats by Keser, Aysegul, Balkan, Burcu, Gozen, Oguz, Kanit, Lutfiye, Pogun, Sakire

“…Abstract NO (nitric oxide) produced in limbic brain regions has important roles in the regulation of autonomic nervous system and HPA axis activity, anxiety,…”
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Forced swim stress elicits region-specific changes in CART expression in the stress axis and stress regulatory brain areas by Balkan, Burcu, Keser, Aysegul, Gozen, Oguz, Koylu, Ersin O, Dagci, Taner, Kuhar, Michael J, Pogun, Sakire

“…Abstract CART mRNA and peptides are highly expressed in the anatomical structures composing the hypothalamo-pituitary-adrenal (HPA) axis and sympatho-adrenal…”
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Region- and sex-specific changes in CART mRNA in rat hypothalamic nuclei induced by forced swim stress by Balkan, Burcu, Gozen, Oguz, Koylu, Ersin O, Keser, Aysegul, Kuhar, Michael J, Pogun, Sakire

“…Abstract Cocaine and amphetamine regulated transcript (CART) mRNA and peptides are highly expressed in the paraventricular (PVN), dorsomedial (DMH) and arcuate…”
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