Search Results - "Goyal, Nadish"

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    RAD54 N-terminal domain is a DNA sensor that couples ATP hydrolysis with branch migration of Holliday junctions by Goyal, Nadish, Rossi, Matthew J., Mazina, Olga M., Chi, Yong, Moritz, Robert L., Clurman, Bruce E., Mazin, Alexander V.

    Published in Nature communications (02-01-2018)
    “…In eukaryotes, RAD54 catalyzes branch migration (BM) of Holliday junctions, a basic process during DNA repair, replication, and recombination. RAD54 also…”
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    Journal Article
  2. 2

    Targeting BRCA1- and BRCA2-deficient cells with RAD52 small molecule inhibitors by Huang, Fei, Goyal, Nadish, Sullivan, Katherine, Hanamshet, Kritika, Patel, Mikir, Mazina, Olga M, Wang, Charles X, An, W Frank, Spoonamore, James, Metkar, Shailesh, Emmitte, Kyle A, Cocklin, Simon, Skorski, Tomasz, Mazin, Alexander V

    Published in Nucleic acids research (19-05-2016)
    “…RAD52 is a member of the homologous recombination (HR) pathway that is important for maintenance of genome integrity. While single RAD52 mutations show no…”
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    Journal Article
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    The Role of N-terminal domain of RAD54 in Branch Migration of Holliday Junctions by Goyal, Nadish

    Published 01-01-2017
    “…Homologous recombination plays an important role in repairing the most harmful types of DNA damage, including DNA double-strand breaks and interstrand…”
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    Dissertation