Search Results - "Goyal, Nadish"
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RAD54 N-terminal domain is a DNA sensor that couples ATP hydrolysis with branch migration of Holliday junctions
Published in Nature communications (02-01-2018)“…In eukaryotes, RAD54 catalyzes branch migration (BM) of Holliday junctions, a basic process during DNA repair, replication, and recombination. RAD54 also…”
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Journal Article -
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Targeting BRCA1- and BRCA2-deficient cells with RAD52 small molecule inhibitors
Published in Nucleic acids research (19-05-2016)“…RAD52 is a member of the homologous recombination (HR) pathway that is important for maintenance of genome integrity. While single RAD52 mutations show no…”
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Journal Article -
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Detection of viral RNAs at ambient temperature via reporter proteins produced through the target-splinted ligation of DNA probes
Published in Nature biomedical engineering (01-12-2023)“…Nucleic acid assays are not typically deployable in point-of-care settings because they require costly and sophisticated equipment for the control of the…”
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Journal Article -
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The Role of N-terminal domain of RAD54 in Branch Migration of Holliday Junctions
Published 01-01-2017“…Homologous recombination plays an important role in repairing the most harmful types of DNA damage, including DNA double-strand breaks and interstrand…”
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Dissertation